INT6062: Strengthening Capacity for Cervical Cancer Control through Improvement of Diagnosis and Treatment INTRODUCTION TO CERVICAL CANCER, FROM A GLOBAL PERSPECTIVE Alfredo Polo MD, PhD (1) & Elena Fidarova MD (2) (1) International Atomic Energy Agency (2) World Health Organisation Radiotherapy in the treatment of locally advanced cervical cancer. Rabat (Morocco), 9-11th May 2018
GLOBOCAN 2012 contains data for cervix, corpus uteri and ovarian cancer
TOTAL FEMALE CANCER (WORLDWIDE) GYNECOLOGIC CANCER BURDEN 6.657.518 NEW CANCER CASES IN WOMEN 1.085.948 NEW GYNECOLOGICAL CASES Cervix 527.624 Others GYN 84 % 16 % Ovary Corpus 238.719 319.605 Source: GLOBOCAN 2012
TOTAL FEMALE CANCER (WORLDWIDE) GYNECOLOGIC CANCER BURDEN GYN GYN 12 % 19 % Others Others 88 % 81 % MORE LESS DEVELOPED COUNTRIES DEVELOPED COUNTRIES Source: GLOBOCAN 2012
TOTAL FEMALE CANCER (WORLDWIDE) GYNECOLOGIC CANCER BURDEN GYN GYN 350.689 735.259 x2 Others Others 88 % 81 % MORE LESS DEVELOPED COUNTRIES DEVELOPED COUNTRIES Source: GLOBOCAN 2012
TOTAL FEMALE CANCER (WORLDWIDE) GYNECOLOGIC CANCER BURDEN Estimated number of incidence cases (thousands), cervix uteri, corpus utery, ovary, in 2012. Source: GLOBOCAN 2012
TOTAL FEMALE CANCER (WORLDWIDE) GYNECOLOGIC CANCER BURDEN Cervix uteri Corpus utery Ovary 800.000 600.000 New cases 2012 400.000 200.000 0 More developed Less developed countries countries
TOTAL FEMALE CANCER (WORLDWIDE) GYNECOLOGIC CANCER BURDEN Cervix uteri Corpus utery Ovary 100 % 75 % New cases 2012 50 % 25 % 0 % More developed Less developed countries countries
WORLDWIDE INCIDENCE OF CERVIX CANCER ESTIMATED AGE-STANDARDIZED RATES OF INCIDENCE CASES, WORLDWIDE IN 2012 Source: GLOBOCAN 2012
INCIDENCE OF CERVIX CANCER BY REGION PROPORTION OF THE TOTAL FEMALE CANCERS 25 % 3 % SUB-SAHARIAN AFRICA EU-28 75 % 97 % Source: GLOBOCAN 2012
TOTAL FEMALE CANCER (WORLDWIDE) GYNECOLOGIC CANCER BURDEN Estimated number of incidence cases (thousands), cervix uteri, corpus utery, ovary, in 2012. Source: GLOBOCAN 2012
World Source: http://globocan.iarc.fr Courtesy F . Bray
Sub-Saharan Africa Courtesy F . Bray
Southern Asia Courtesy F . Bray
South and Central America Courtesy F . Bray
2030 projection: Cervical cancer crisis in LMICs 700000 400000 525000 300000 Less Developed 350000 200000 More Developed 175000 100000 0 0 2012 2030 2012 2030 GLOBOCAN 2012 Incidence Mortality
Cervical cancer: inequity in numbers • The second most common female cancer in less developed countries • In 2012, 528 000 new cases of cervical cancer were diagnosed, and 266 000 women died of the disease • Almost 90% of all cervical cancer cases occur in less developed regions of the world • Cervical cancer represents 10% of the total number of all cancer cases in LMIC • 9 of 10 deaths of all cervical cancer cases occur in in less developed regions of the world • Mortality varies 18-fold between more and less developed regions of the world
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