IHI Expedition Expedition: Improving Medication Safety from the - - PowerPoint PPT Presentation

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IHI Expedition Expedition: Improving Medication Safety from the - - PowerPoint PPT Presentation

February 26, 2015 These presenters have nothing to disclose IHI Expedition Expedition: Improving Medication Safety from the Patients Perspective Session 1: Improving Polypharmacy E. Robert Feroli Jr., PharmD, FASHP Amanda Brummel,


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IHI Expedition

Expedition: Improving Medication Safety from the Patient’s Perspective Session 1: Improving Polypharmacy February 26, 2015

These presenters have nothing to disclose

  • E. Robert Feroli Jr.,

PharmD, FASHP Amanda Brummel, PharmD, BCACP Frank Federico, RPh Joelle Baehrend

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Today’s Host

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Dorian Burks, Project Coordinator, Institute for Healthcare Improvement, is a current coordinator for web-based Expeditions. He also contributes to the IHI work in the Triple Aim and Improvement Capability focus areas, as well as the Leading Quality Improvement series. Dorian is a member of the Diversity and Inclusion Council at IHI, where he and fellow staff members develop strategies to enhance IHI’s inclusive culture, both internally and externally. Dorian graduated from Massachusetts Institute of Technology in Cambridge, MA where he received his Bachelor of Science degree in Biology and humanities concentration in Anthropology.

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Audio Broadcast

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You will see a box in the top left hand corner labeled “Audio broadcast.” If you are able to listen to the program using the speakers on your computer, you have connected successfully.

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Phone Connection (Preferred)

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T

  • join by phone:

1) Click on the “Participants” and “Chat” icons in the top right hand side of your screen. 2) Click the button

  • n the right hand side of

the screen. 3) A pop-up box will appear with the option “I will call in.” Click that

  • ption.

4) Please dial the phone number, the event number and your attendee ID to connect correctly .

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WebEx Quick Reference

  • Please use chat to

“All Participants” for questions

  • For technology

issues only, please chat to “Host”

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Enter Text Select Chat recipient Raise your hand

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Chat

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Name and the Organization you represent Example: Sam Jones, Midwest Health

Please send your message to All Participants

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Where are you joining from?

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For more information or to enroll, email Passport@ihi.org

By joining Passport, your entire staff gets access to a wide range of web-based tools to help prioritize, deploy, and accelerate your improvement initiatives without leaving your desks. Passport membership will:

  • Bring IHI's world-class expertise to your doorstep (virtually) and support

multiple teams closest to the point of care as they make rapid improvements in the areas of greatest concern to hospitals today.

  • Help your staff meet its continuing education requirements for physicians,

nurses, and pharmacists.

  • Give your middle managers the skills they need to guide your
  • rganization's efforts to improve patient care and achieve its strategic goals.
  • Save you time, set your teams up for success, and facilitate more effective

use of your resources.

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SLIDE 9

IHI Open School Courses

  • More than 20 online courses developed by world-

renowned experts in the following topics

Improvement Capability

Patient Safety

Person- and Family-Centered Care

Triple Aim for Populations

Quality, Cost, and Value

Leadership

  • More than 26 continuing education contact hours for

nurses, physicians, and pharmacists. NAHQ has also approved the courses for CPHQ CE credit.

  • Basic Certificate of Completion available upon

completion of 16 foundational course.

  • Mobile App for iPhone and iPad
  • 20% Discount on organizational subscription for

Passport Members

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What is an Expedition?

ex•pe•di•tion (noun)

  • 1. an excursion, journey, or voyage made for some specific

purpose

  • 2. the group of persons engaged in such an activity
  • 3. promptness or speed in accomplishing something
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Expedition Director

Joelle Baehrend, Fellowship Director, IHI, is also a developer for IHI’s Patient Safety Focus Area. She was previously a project manager for the 100,000 Lives Campaign and platform lead for the 5 Million Lives

  • Campaign. Baehrend’s other work at IHI has included

participation on IHI’s business team, product development, including the satellite broadcast of IHI’s National Forum on Quality Improvement in Health Care, as well as project management for the Improving Flow Through Acute Care Settings IMPACT Community. Baehrend received a Master of Arts in English literature from Indiana University of Pennsylvania in 1996 and served as adjunct faculty at Massasoit Community College before joining IHI in 2000.

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Chat

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What is your goal for participating in this Expedition?

Please send your message to All Participants

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Today’s Agenda

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  • Ground Rules & Introductions
  • Pre- Survey Debrief
  • Improving Polypharmacy
  • Action Period Assignment
  • IHI’s Model for Improvement
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Ground Rules

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  • We learn from one another – “All teach, all

learn”

  • Why reinvent the wheel? - Steal shamelessly
  • This is a transparent learning environment
  • All ideas/feedback are welcome and

encouraged!

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Expedition Objectives

At the conclusion of this Expedition, participants will be able to:

Explain the importance of including patients and their families in efforts to improve medication safety Identify different approaches to improve medication safety Describe examples of medication safety improvement efforts at other organizations Plan tests of change to begin or continue medication safety improvement

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Schedule of Calls

Session 1 – Improving Polypharmacy Date: Thursday, February 26, 1:00 – 2:30 PM Eastern Time Session 2 – Health Literacy and Medication Safety Date: Thursday, March 12, 1:00 – 2:00 PM Eastern Time Session 3 – Improving Medication Adherence Date: Thursday, March 26, 1:00 – 2:00 PM Eastern Time Session 4 – Medication Reconciliation Date: Thursday, April 9, 1:00 – 2:00 PM Eastern Time Session 5 – Safe Management of Newly Released Anticoagulants and High-Alert Medications Date: Thursday, April 23, 1:00 – 2:00 PM Eastern Time

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Pre-Work Assignment & Survey Results

  • Complete the IHI Open School Course QI 102: The

Model For Improvement: Your Engine for Change

  • Complete the Expedition: Improving Medication

Safety from the Patient’s Perspective Pre- Survey

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Survey Results - Themes

Top three barriers to improving medication safety:

  • Staff resources
  • Medication reconciliation (at transitions in levels of care;

resolving discrepancies; identifying the most reliable list)

  • Cultural challenges; resistance to change

Top two barriers to engaging patients in this work:

  • Patient education and health literacy
  • Time

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Survey Results - Themes

Points of pride in improving medication safety:

  • Medication reconciliation form in patients’ admin records
  • Unit based pharmacists
  • Technology – computerized medication systems, smart

pumps CPOE, barcoding

  • Color coding for high risk medications

What are you hoping to learn in this Expedition?:

  • General improvement ideas
  • More reliable processes for medication reconciliation
  • Ways to engage patients in improving medication safety
  • Learn from others doing this work

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Survey Results - Current State

My hospital has a process to address medication management and reduce polypharmacy where appropriate.

  • Do not know current status of this practice: 5%
  • Do not currently have this practice in place: 11%
  • Have a process that supports this practice: 47%
  • Process is reliably applied: 11%
  • Need further clarification on this practice: 26%

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Faculty

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Frank Federico, RPh, Executive Director, Strategic Partners, Institute for Healthcare Improvement (IHI), works in the areas of patient safety, application of reliability principles in health care, preventing surgical complications, and improving perinatal care. He is faculty for the IHI Patient Safety Executive Training Program and co-chaired a number of Patient Safety

  • Collaboratives. Prior to joining IHI, Mr. Federico was the Program

Director of the Office Practice Evaluation Program and a Loss Prevention/Patient Safety Specialist at Risk Management Foundation of the Harvard Affiliated Institutions, and Director of Pharmacy at Children's Hospital, Boston. He has authored numerous patient safety articles, co-authored a book chapter in Achieving Safe and Reliable Healthcare: Strategies and Solutions, and is an Executive Producer of "First, Do No Harm, Part 2: T aking the Lead." Mr. Federico serves as Vice Chair of the National Coordinating Council for Medication Error Reporting and Prevention (NCC-MERP). He coaches teams and lectures extensively, nationally and internationally, on patient safety.

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Improving Polypharmacy

  • E. Robert Feroli and Amanda Brummel

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Faculty

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  • E. Robert (Bob) Feroli Jr., PharmD, FASHP has been a

pharmacist at Johns Hopkins Hospital for 36 years and has served as a Medication Safety Officer for the past 11 years. He established a Medication Use Safety Pharmacy Residency (accredited by ASHP). Dr. Feroli teaches on topics

  • f safe medication use practices and rational therapeutics,

and has faculty appointments at the Johns Hopkins University Schools of Medicine and Nursing, and the University Of Maryland School Of Pharmacy. Dr. Feroli also participates in error prevention efforts, investigations of errors, and serves as chairman of the Medication Error Reduction Implementation T eam (MERIT). He also works with 12 international hospitals that have formed affiliations with Johns Hopkins on using the medication use system to improve safety, efficiency, therapeutic appropriateness, and compliance with Joint Commission International (JCI) standards.

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Faculty

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Amanda Brummel, PharmD, BCACP serves as the Director of Clinical Ambulatory Pharmacy Services. Dr. Brummel has been employed by Fairview Pharmacy Services since 1999 when she graduated from the University of Minnesota. While at Fairview, she has built and practiced Medication Therapy Management (MTM) in multiple clinic locations, was the clinical supervisor for the MTM department, the MTM Operations & Program Manager. Currently Dr. Brummel has responsibility for the MTM program, the clinical development and integration of pharmacy services in the Fairview Health Network including our transitions of care approach and our retail clinical services. She works closely with the Fairview Medical Group and the Fairview Network in our population health approach and new payer product development. Dr. Brummel is also an Adjunct Associate Professor at the University of MN. She has published multiple articles on MTM and pharmacy’s role in the care team. She has chaired and served on multiple committees and is a current member of the Minnesota Pharmacists Association, the American Society of Health-System Pharmacists, the American College of Clinical Pharmacy and Pharmacy Quality Alliance (PQA).

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Polypharmacy

Bob Feroli, PharmD, FASHP, FSMSO

Medication Safety Officer Department of Pharmacy Johns Hopkins Hospital

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Polypharmacy

National Center for Health Statistics Data Brief No.42 Sept 2010

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Polypharmacy

  • As patients get sicker (regardless of age), the number of

clinically appropriate medications generally goes up.

  • As number of medications goes up, potential medication

related problems go up

– Adverse drug effects – Drug – Drug interactions – Drug – Disease interactions – Possibility of medication errors – Poor adherence – Cost of therapy – Poor quality of life (e.g., pill burden)

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Polypharmacy

  • So what is “Polypharmacy”?
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Polypharmacy

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Polypharmacy

Homoeopathy Polypharmacy - A prescription of many drugs in one compound

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Polypharmacy

Illinois and Indiana Medical and Surgical Journal, Volume 1, Issue 1 (1846) Reform Practical Therapeutics Agenda item #6 – “To endeavor to substitute for the monstrous system of Polypharmacy now universally prevalent, one that is, at least, vastly more simple, more intelligible …”

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I take aspirin for the headache caused by the Zyrtec I take for the hayfever I got from Relenza from the uneasy stomach from the Ritalin I take for the short attention span caused by the Scopederm Ts I take for the motion sickness I got from the Lomotil I take for the diarrhea caused by the Zenikal for the uncontrolled weight gain from the Paxil I take for the anxiety from the Zocor I take for my high cholesterol because exercise, a good diet, and regular chiropractic care are just too much trouble.

  • Dr. Jonathan Lazar (Lazar Spinal Care, P

.C.)

Image reproduced with permission

Polypharmacy

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I take aspirin for the headache caused by the Zyrtec I take for the hayfever I got from Relenza from the uneasy stomach from the Ritalin I take for the short attention span caused by the Scopederm Ts I take for the motion sickness I got from the Lomotil I take for the diarrhea caused by the Zenikal for the uncontrolled weight gain from the Paxil I take for the anxiety from the Zocor I take for my high cholesterol because exercise, a good diet, and regular chiropractic care are just too much trouble.

  • Dr. Jonathan Lazar (Lazar Spinal Care, P

.C.)

Image reproduced with permission

Polypharmacy

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Polypharmacy

Bushart RL, Massey EB, et.al., Polypharmacy; Misleading, but manageable. Clinical Interventions in Aging 2008:3(2) 383-389 Review of literature Jan 1997 – May 2007

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  • Over 24 distinct definitions Clin. Intervent. In Aging 2008:3(2) 383-389

– Potentially Inappropriate

Polypharmacy

Bushart RL, Massey EB, et.al., Polypharmacy; Misleading, but manageable. Clinical Interventions in Aging 2008:3(2) 383-389 Review of literature Jan 1997 – May 2007

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  • Over 24 distinct definitions Clin. Intervent. In Aging 2008:3(2) 383-389

– Potentially Inappropriate

  • Medication used to treat a side effect of another medication

Polypharmacy

Bushart RL, Massey EB, et.al., Polypharmacy; Misleading, but manageable. Clinical Interventions in Aging 2008:3(2) 383-389 Review of literature Jan 1997 – May 2007

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Polypharmacy

  • Over 24 distinct definitions Clin. Intervent. In Aging 2008:3(2) 383-389

Potentially Inappropriate

  • Medication used to treat a side effect of another medication
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Polypharmacy

  • Over 24 distinct definitions Clin. Intervent. In Aging 2008:3(2) 383-389

Potentially Inappropriate

  • Medication used to treat a side effect of another medication
  • Using many (2,3,5,6 . . .) medications
  • More than one medication to treat the same condition
  • Using a medication that interacts with one another medication
  • Medications prescribed more that twice daily
  • Taking an OTC medication
  • Obtaining medications from more than one pharmacy
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Polypharmacy

  • Over 24 distinct definitions Clin. Intervent. In Aging 2008:3(2) 383-389

Potentially Inappropriate

  • Medication does not match a diagnosis
  • Dose of medication does not match renal or liver function
  • Equally effective less costly (& not more toxic) alternative is available
  • Unnecessary duplication of therapy
  • Complicated regimen affecting adherence
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Polypharmacy

  • Over 24 distinct definitions Clin. Intervent. In Aging 2008:3(2) 383-389

Potentially Inappropriate?

  • Medication does not match a diagnosis
  • Dose of medication does not match renal or liver function
  • Equally effective less costly (& not more toxic) alternative is available
  • Unnecessary duplication of therapy
  • Complicated regimen affecting adherence
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Polypharmacy

  • Over 24 distinct definitions Clin. Intervent. In Aging 2008:3(2) 383-389

Potentially Inappropriate?

  • Medication does not match a diagnosis
  • Dose of medication does not match renal or liver function
  • Equally effective less costly (& not more toxic) alternative is available
  • Unnecessary duplication of therapy
  • Complicated regimen affecting adherence

– Therapeutically appropriate therapy vs. patient's ability to adhere to therapeutic regimen

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Polypharmacy

  • Over 24 distinct definitions Clin. Intervent. In Aging 2008:3(2) 383-389

Potentially Inappropriate?

  • Medication does not match a diagnosis
  • Dose of medication does not match renal or liver function
  • Equally effective less costly (& not more toxic) alternative is available
  • Unnecessary duplication of therapy
  • Complicated regimen affecting adherence

– Therapeutically appropriate therapy vs. patient's ability to adhere to therapeutic regimen » The simplest most appropriate therapeutic regimen for a particular patient may be too complex for them to follow.

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Polypharmacy

  • Over 24 distinct definitions Clin. Intervent. In Aging 2008:3(2) 383-389

Potentially Inappropriate?

  • Medication does not match a diagnosis
  • Dose of medication does not match renal or liver function
  • Equally effective less costly (& not more toxic) alternative is available
  • Unnecessary duplication of therapy
  • Complicated regimen affecting adherence

– Therapeutically appropriate therapy vs. patient's ability to adhere to therapeutic regimen » The simplest most appropriate therapeutic regimen for a particular patient may be too complex for them to follow. » We must use a risk : benefit approach to find the most appropriate therapy given the patient’s values and ability to adhere to the chosen regimen.

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Polypharmacy

  • Medication regimens should optimize for:

– Clinical Appropriateness – Safety – Affordability – Ease of use – Patient’s ability & willingness to adhere

  • Concurrent method to promote rational therapeutics

– Reconciliation: Based on the response from medications taken “yesterday.” What, if any, changes are appropriate going forward.

  • Retrospective- “triggers” to identify potentially inappropriate therapy

– Polypharmacy (e.g., patient on more than x drugs) – IHI trigger tool – Beer’s criteria – STOPP (Screening Tool of Older People’s Prescriptions) – START (Screening Tool to Alert to Right Treatment)

Seek the “sweet spot”

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Comprehensive Medication Management

Amanda Brummel PharmD, BCACP Director, Clinical Ambulatory Services Fairview Pharmacy Services

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February 26, 2015

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Practitioners’ responsibilities:

  • To identify a patient’s drug-related needs and commit

to meet those needs

  • To ensure that all of a patient’s drug therapy is

appropriately indicated, the most effective, the safest and the patient is compliant

  • To work in collaboration with all members of a

patient’s care team

Pharmacy Strategies

Foundation of Comprehensive Medication Management (CMM)

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Comprehensive Medication Management

Built upon the philosophy and process of “pharmaceutical care practice”

ASSESSMENT CARE PLAN EVALUATION

  • Ensure all drug therapy is

indicated, effective, safe and convenient

  • Identify drug therapy

problems

  • Resolve drug therapy

problems

  • Establish therapeutic goals
  • Prevent drug therapy

problems

  • Record actual patient
  • utcomes
  • Evaluate progress in

meeting therapeutic goals

  • Reassess for new problems

Continuous Follow-up

Working in collaboration with all members of the healthcare team

ESTABLISH A THERAPEUTIC RELATIONSHIP

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Assessment

  • Establish therapeutic relationship
  • Understand patient’s goals of

therapy

Meet the patient

  • Reason for encounter
  • Patient history, medication

experience, clinical information

Elicit relevant information

  • Indication, efficacy, safety,

convenience

Make drug therapy decisions

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  • Unnecessary drug therapy?
  • Additional drug therapy needed?

INDICATION

  • Ineffective drug?
  • Dosage too low?
  • Drug interaction reducing efficacy?

EFFICACY

  • Adverse drug reaction?
  • Dosage too high?
  • Drug interaction increasing toxicity?

SAFETY

  • Willingness to take medications?
  • Ability to take medications?

COMPLIANCE

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Care Plan

  • Clinical goals
  • Drug therapy goals

Establish goals of therapy

  • Non-drug therapy, education
  • Patient-specific drug choices

Interventions: DTP resolutions, achieving goals of therapy, achieving patient goals prevention of DTP

  • Patient specific and clinically

appropriate

  • Method of follow-up

Schedule follow-up evaluation

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Follow-up evaluation

  • Evaluate effectiveness of drug

therapy

Compare actual patient outcomes to goals

  • Evaluate safety and patient’s ability

to adhere to therapy

  • Explore reasons for non-adherence

Monitor for adverse effects and compliance

  • Assess for changes in condition

status and drug therapy

Assess for new drug therapy problems

  • Continuous care

Schedule next follow-up

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Drug Therapy Problems Identified

2014

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Dosage Too Low 31 % Needs Additional Drug Therapy 21 % Noncompliance 15 % Adverse Drug Reaction 11 % Dosage Too High 10 % Unnecessary Drug Therapy 8 % Ineffective Drug 6 %

19,963 Drug Therapy Problems Resolved

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Confirmation of DTPs

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Estimated Cost Interventions

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Fairview Published Results

  • An average 12-to-1 return on investment in terms of reduced overall

health-care costs, documented in “Clinical and Economic Outcomes

  • f Medication Therapy Management Services: The Minnesota

Experience” (Isetts, et al., J Am Pharm Assoc. 2008;48(2):203-211)

  • MTM contributed to optimal care in complex patients with diabetes

documented in “Optimal Diabetes Care Outcomes Following Face- to-Face Medication Therapy Management Services” (Brummel A.R. et al, Population Health Management: 2012)

  • Medication therapy management: 10 years of experience in a large

integrated health care system. (Ramalho de Oliveira, D., Journal of Managed Care Pharmacy : JMCP, 16(3), 185-195.)

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Health Care Costs After MTM

$0 $2,000 $4,000 $6,000 $8,000 $10,000 $12,000

Facilities (-57.9%) Professional (-11.1%) Prescriptions (+ 19.5%) Total Cost (-31.5%)

1 Year before MTM 1 Year after MTM

Isetts, et al., J Am Pharm Assoc. 2008;48(2):203-211

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Optimal Diabetes Care Outcomes

2006 Pre-MTM, 2007 MTM, 2008 Post-MTM

“Optimal Diabetes Care Outcomes Following Face-to-Face Medication Therapy Management Services” (Brummel A.R. et al, Population Health Management: 2012)

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Activation, Engagement, and Shared Decision-Making

  • Patient activation

 Measure of patient’s knowledge, skills, and ability to manage their health

  • Patient engagement

 Steps patients take on their own  Combines ‘activation’ with interventions

  • Promote positive patient behavior
  • Obtaining preventive care or exercising
  • Shared decision making—Patients and providers together

 Patient’s condition, treatment options, the medical evidence behind treatment options, risks and benefits, and patients’ preferences, arrive at treatment plan

Robert Wood Johnson Foundation. Patient Engagement. February 14, 2013. http://healthaffairs.org/healthpolicybriefs/brief_pdfs/healthpolicybrief_86.pdf. Accessed September 5, 2014.

Patients who had decision-making support

  • Overall medical

costs were 5.3% lower

  • 12.5%

fewer hospital admissions

  • 20.9%

fewer preference-sensitive heart surgeries

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SLIDE 60

Activation Level and Cost

  • PAM scores were predictive of billed costs of care
  • With targeted interventions, least activated patients realize

the greatest gains

  • Care for patients with Level 1 Activation cost 8-21% more

than patients with Level 2-4

 Some variance by condition

  • Costs for Level 1 patients with hypertension were 14%

higher than Level 4

  • Costs for Level 1 patients with asthma were 21% higher

than Level 4  Caveat: Predicted costs were no different for patients at Level 2-4

Health Affairs, 32, no.2, 2013. Judith H. Hibbard. Patients With Lower Activation Associated With Higher Costs. http://content.healthaffairs.org/content/32/2/216.full.html. Accessed September 7, 2014.

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Key Points

  • Comprehensively review a patient’s medication therapy

 Look to make sure each medication is

  • Indicated
  • Effective
  • Safe
  • Convenient/Compliance
  • Consider a patient’s medication experience
  • Engage them in the decision making process when

choosing their medication therapy

  • Follow up to evaluate their outcomes and assess for new

drug therapy problems

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Questions/Discussion

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Raise your hand Use the chat

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Action Period Assignment

Research and consider what your facility has in place to optimize medication use and minimize polypharmacy.

– Please be prepared to share on our next session

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Expedition Communications

  • All sessions are recorded
  • Materials are sent one day in advance
  • Listserv address for session communications:

MedicationSafety@ls.ihi.org

  • To add colleagues, email us at info@ihi.org

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Session 2

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Thursday, March 12, 1:00 PM ET

Health Literacy and Medication Safety

Gail Nielsen, BSHCA, FAHRA Fellow and Patient Safety Scholar at IHI

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SLIDE 66

Thank You!

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Joelle Baehrend jbaehrend@ihi.org Dorian Burks dburks@IHI.org

Please let us know if you have any questions or feedback following today’s Expedition webinar.

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SLIDE 67

Consider video

  • Dr. Mike Evans Video: An Illustrated Look at Quality

Improvement in Health Care http://www.ihi.org/resources/Pages/AudioandVideo/MikeEv ansVideoQIHealthCare.aspx

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What are we trying to accomplish? How will we know that a change is an improvement? What change can we make that will result in improvement?

Model for Improvement

Act Plan Study Do

Aim of Improvement Measurement

  • f

Improvement Developing a Change Testing a Change

Adapted from Langley, G. J., Nolan, K. M., Nolan, T. W., Norman, C. L., & Provost, L. P. The Improvement Guide: A Practical Approach to Enhancing Organizational

  • Performance. San Francisco, CA: Jossey-Bass, 1996.
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The Medical Model and the Model for Improvement

Medical Model Collect signs and symptoms Develop a treatment plan Prescribe the plan Collect signs and symptoms to determine if there is improvement Model for Improvement Collect pre-data to understand the extent of the problem Select process changes to be tested Test the changes Collect post-data to determine if there is improvement

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Why Test?

  • Increase the belief that the change will result in

improvement

  • Predict how much improvement can be

expected from the change

  • Learn how to adapt the change to conditions in

the local environment

  • Evaluate costs and side-effects of the change
  • Minimize resistance upon implementation
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SLIDE 71

Repeated Use of the PDSA Cycle

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Hunches Theories Ideas Changes that Result in Improvement

A P S D A P S D

Very Small Scale Test Follow-up Tests Wide-Scale Tests

  • f Change

Implementation of Change Sequential building of knowledge under a wide range

  • f conditions

Spread

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SLIDE 72

Multiple PDSA Cycle Ramps

Transfusion Administration Safety Communication and Awareness Strategies Engaging with Leadership

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Implementing Transfusion Guidelines

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Final Questions/Discussion

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Raise your hand Use the chat