global community Steen Skjold Jorgensen, Vice president , R&D - - PowerPoint PPT Presentation

Biofuels R&D – a global community

Steen Skjold Jorgensen, Vice president , R&D Novozymes North America

Gene Expression (rDNA technology) Process Development Expression Profiling; DNA Microarrays Protein Chemistry Assay technologies Pathway Engineering Microbial Diversity Gene Diversity Artificial Evolution High throughput screening Protein Engineering: Structure / Function relationships Bio-Informatics: HTS sequencing & gene identification

Large Scale Fermentation, Product Recovery, Formulation

NOVOZYMES INTEGRATES ALL THE COMPETENCES INVOLVED IN PROVIDING COST EFFECTIVE BIOLOGICAL SOLUTIONS

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More than 150 employees dedicated to 2G biofuels

• 1000 R&R people WW
• 14 % of turnover ploughed back to R&D
• Groundbreaking technology for grain based ethanol
• Large global effort in cellulosic ethanol (2G) – around 150 in R&D – the

largest single project ever.

• More than 300 patents granted and more than 200 patent families

submitted for biofuels to date – and growing

• Also active in Biodiesel as well as Biogas developmental activities.

Our commitment to the Bioenergy field begins with our global R&D efforts

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TYPICAL 1. GEN. FUEL ETHANOL PROCESS

31 C 85 C 85 C 85 C 105 C 33 C 80 C 33 C

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BPX (RAW STARCH BASED) FUEL ETHANOL PROCESS

31 C 33 C 33 C 80 C 33 C

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Roles of GA and AA in BPX process

AA

10 20 30 40 50 60 70 80 90 100 relative enzyme dose BPX initial 1st Gen 2nd Gen 3rd Gen conv

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Enzyme cost in use improvements

Time & effort Protein need Novozymes launched Cellic CTEC 2 in 2010 as a result of 10 years miltidisciplinary research

Application Discovery Production

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pre-treatment

Hydrolysis

fermentation

• Highly interrelated technologies
• Novozymes R&D tools and experience

utilizing enzyme technology and application know-how to also provide ideas in p and f

• Partnership is key

Collection & Storage Recovery

Applied Discovery Reduce total process costs – focus on enzyme costs via holistic innovation

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• Poet
• Greenfield
• ICM
• Dedini
• Inbicon
• M&G
• Lignol
• PRAJ
• COFCO & Sinopec
• Fiberight

Deployment in collaboration with partners

• Novozymes key global cellulosic ethanol partners
• ADM
• Nedalco
• CTC
• Petrobras
• Ceres

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CELLULOSIC ETHANOL TECHNOLOGY IS REACHING COMMERCIALIZATION

• Production costs for cellulosic ethanol are becoming competitive with

gasoline and starch/sugar based ethanol

• Capital costs must be balanced with operational expenses

Novozymes Cellic CTec2 delivers on our 2010 promise by reducing the enzyme dose significantly to a level where cellulosic ethanol can be made economically

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NZNA R&D: Competency center within Bioenergy processes– Tour our wetlab!

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