Genome 562 February 2015 Week 6 Genome 562 p.1/13 Julian Huxley - - PowerPoint PPT Presentation

Genome 562

February 2015 Week 6

Genome 562 – p.1/13

Julian Huxley (1887-1975)

Oxford University, 1922 about 1960

Genome 562 – p.2/13

Sewall Wright (1889-1988)

At the University of Chicago, 1929

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With guinea pig and equations, 1955

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Path coefficient diagram (Wright, 1921)

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B C D

E G

H

AA Aa aa AA Aa AA

Genome 562 – p.6/13

C E G

H

c’

e

g

c

Genome 562 – p.7/13

B

C D

E H

G

I

b

b’

c

d

e

e’ d’

g h

Genome 562 – p.8/13

E B C D

F F F BE CE DE

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t t−1 t+1 generation

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Reccurrent sib-mating

1 2 3 t

Generation

kt ht t l

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(non-)IBD from recurrent sib-mating

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On a log scale ...

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