Feasibility study of TULIP: a TUrning LInac for Protontherap LInac - - PowerPoint PPT Presentation

Feasibility study of TULIP: a TUrning LInac for Protontherap LInac for Protontherapy

ICTR ICTR-

• PHE 2012 Conference

PHE 2012 Conference 28.02.2012

• A. Degiovanni
• U. Amaldi, M. Garlasché, K. Kraus, P. Magagnin, U. Oelfke,
• P. Posocco, P. Riboni, V. Rizzoglio

TULIP: a Single Room Facility project TULIP: a Single Room Facility project

 Why single room facilities ?

– Proton therapy beneficial to at least 12% of X-ray patients (ENLIGHT studies outcome) (ENLIGHT studies outcome) – ~ 2.400 patients/year every 10'000'000 people – 1 proton room every 1.5 Milion inhabitants p y

 Advantages

– Spread the investement cost – Hospital based protontherapy (not dedicated centres)

 Technical challenges

Size and cost of the machine – Size and cost of the machine – Dose delivery modalities – Treatment time

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A A cyclinac cyclinac based based solution solution

TULIP = TU i LI f C-band linac C-band linac Section 1 TUrning LInac for Protontherapy C band linac Section 2 Section 1 cyclotron Line with 2% momentum acceptance y acceptance B d RF rotating joints Beam dose delivery RF Power sources Mechanical structure

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The CYCLINAC timeline The CYCLINAC timeline

1993: first Cyclinac proposal proposal 2007: first

* See abs. #227 by S. Verdú Andrés

2003: test on LIBO-62 MeV (TERA-CERN-INFN) CABOTO design 2010: 2010: CABOTO-C design (*) 11.2010: LIGHT 1st UNIT inaugurated by CERN DG

• Prof. R. Heuer

(courtesy of ADAM SA )

 [U Amaldi S Braccini and P Puggioni

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ADAM SA.)

 [U. Amaldi, S. Braccini and P. Puggioni, RAST Vol 2 (2009) 111-131]

The The linac linac and RF system and RF system

Electric field di t ib ti (HFSS)

• acc. cell
• n axis
• coupl. cell
• n side

distribution (HFSS)

• acc. tanks

excited cavity

TANK

space for quadrupoles un-excited cavity

 RF cavities in π/2 mode  Accelerating TANKS  Acc. units with space for PMQs  H11 polarizer (Igor Syratchev, CERN)

linear l i ti circular l i ti

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polarization polarization

The CYCLINAC timeline The CYCLINAC timeline

1993: first Cyclinac proposal proposal 2007: first

* See abs. #227 by S. Verdú Andrés

2003: test on LIBO-62 MeV (TERA-CERN-INFN) CABOTO design 2010: 2010: CABOTO-C design (*) 11.2010: LIGHT 1st UNIT inaugurated by

E0 = 15 MV/m

CERN DG

• Prof. R. Heuer

(courtesy of ADAM SA )

 [U Amaldi S Braccini and P Puggioni

E0 = 16 MV/m

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ADAM SA.)

 [U. Amaldi, S. Braccini and P. Puggioni, RAST Vol 2 (2009) 111-131]

The choice of the frequency The choice of the frequency

 TULIP project requires shorter linacs p j q

 Higher gradients are needed (~35 MV/m)

 Reliability in terms of BDR

 High gradient tests (S- and C- band) in collaboration with CLIC collaboration with CLIC see poster #203 (Cyclinac group)

 Size of RF rotating joints for power transmission p  Power source availability

 C-

• band : 5.712 GHz

band : 5.712 GHz

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TULIP preliminary design TULIP preliminary design

@5.7 GHz (C-band) from 35 to 210 MeV Quantity [unit] Section 1 Section 2 Output energy [MeV] 80 210 Total length [m] 3.9 5.9 g [ ]

• Avg. E0 [MV/m]

20-24 32-38

• Max. ESURFACE [MV/m]

150 170 Number of units 1 (4) 7 Peak Power [MW] 25 84 Repetition rate [Hz] 200 200 Repetition rate [Hz] 200 200 Pulse length [μs] 2.5 2.5

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Fast active energy variation Fast active energy variation

E) (E) / N(E dN( Energy [MeV]

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Fast Fast active active energy energy variation variation

 Active energy variation in the range 80-210 MeV  Energy spread within 2 mm distal fall-off

 Active spot scanning with Active spot scanning with tumour tumour multipainting multipainting

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TULIP TULIP beam beam transfer transfer line line

p E R      5 3 8 1 With Δp/p = ±2%  ΔR/R = ± 7% p E R   5 . 3 8 . 1

For R = 30 cm  ΔR = ± 2.1 cm 30 5 28.2 32.9 29.4 cm 31.7 cm 30.5 cm cm cm

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Supporting structure Supporting structure

C-band linac linac

Section I [kg] Section II [kg] Linac 340 460 Linac 340 460 Beam Structure 3400 4800 Ancillaries 640 860

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TULIP Mechanical Design TULIP Mechanical Design

Bearings Rot axis

• Rot. axis

Actuators 1 2 3 1 3

Total estimated 60 weight [tons] 60 Max ang acceleration 0.5 acceleration [rad/s2] 0.5 Max rotation speed* [rpm] 1.5

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speed [rpm]

* derived from norm EN 60601 and max vel considerations

Novel Novel study study of

• f dynamic

dynamic dose dose delivery delivery

• simulation of dynamic delivery via computer software
• based on treatment plan data for a static dose delivery
• dynamic parameters (repetition rate, vGantry , vCouch)

Plan data: Dij matrices

ij

Spot positions Spot weights Dynamic dose l l ti Dose di t ib ti TPS: Calculation of Tulip machine parameters: Gantry speed calculation distribution static plan y Repetition rate Couch speed Number of protons

 more information: Poster 156 by Kim Kraus (DKFZ Heidelberg)  more information: Poster 156 by Kim Kraus (DKFZ, Heidelberg)

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Novel Novel study study of

• f dynamic

dynamic dose dose delivery delivery

• dynamic dose delivery to a

cylindrical target volume cylindrical target volume

• different combinations of dynamic

parameters the higher the gantry speed the the higher the gantry speed the higher must be the repetition rate to deliver all spots

DDiff = Ddyn(f= 100Hz, vGantry = 1°/s) - Dstatic

Difference dose distribution : Good agreement of the dynamic and static dose distributions within the target!

28.02.2012

within the target!

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Summary Summary

First design in C-band for a single room facility:  Linac and RF design  M h i l d i

Cyclinac

 Mechanical design  Novel dose delivery

concept

Future developments: Optimization of Section 1

TULIP

New dose delivery Compact beam line

• Optimization of Section 1
• Final mechanical spec.

de e y beam line

 Combine acceleration Combine acceleration d t fl ibilit ith d t fl ibilit ith

New mechanical design

and gantry flexibility with and gantry flexibility with active energy variation active energy variation

g

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