Elizabeth Iorns, Ph.D. Co-Founder Science Exchange is an online - PowerPoint PPT Presentation

Elizabeth Iorns, Ph.D. Co-Founder

Science Exchange is an online marketplace for science experiments

Why did we build Science Exchange? ➡ personal experience as a researcher ➡ major increases in multi-institutional co-authored publications ➡ broader trends towards increased specialization and multi-disciplinary research All indicate collaborations and partnerships are becoming increasingly important

Scientific collaborations and partnerships are currently ad hoc ➡ barter to colleagues or network ➡ use (suboptimal) internal core facility ➡ use Google to find external service provider

Science Exchange makes collaborations and partnerships easy Science experiments-as-a-service

Science Exchange is about connecting scientists...

... and making it easy for them to work together POST A BID ON EVALUATE PROJECT PROJECTS & CHOOSE PLUS: ‣ PROJECT MANAGEMENT ‣ PAYMENT PLATFORM

“eBay for Science”?

“eBay for Science”? ➡ made it easier for ➡ hoping to make it easier for scientists to form consumers to trade collaborations and second-hand goods partnerships ➡ dramatically increased ➡ hoping to dramatically size of market for increase amount of second-hand goods collaboration in science

So what does this have to do with Open Science?

Open Science often characterized as getting scientific data into the public sphere ASAP

Some key principles of Open Science... ➡ Transparency ➡ Access ➡ Efficiency ➡ Reproducibility

...are also key principles of Science Exchange ✔ ➡ Transparency ✔ ➡ Access ✔ ➡ Efficiency ✔ ➡ Reproducibility

Some key principles of Science Exchange ✔ ➡ Transparency ✔ ➡ Access ✔ ➡ Efficiency ✔ ➡ Reproducibility

Transparency $500 $1,000 $1,500 $2,000 $2,500 $3,000 $3,500 $4,000 SNP Array for GWAS NGS library generation NGS paired end HiSeq 2000 Sanger DNA sequencing Illumina microarray Affymetrix microarray Bioinformatics IHC of tissue sections Transgenic mouse production Scientists are not aware of these price differences

Transparency “B Y USING S CIENCE E XCHANGE WE WERE ABLE TO SAVE HALF THE COST ON THIS PARTICULAR TYPE OF EXPERIMENT ”

Transparency Science Exchange can bring transparency allowing everyone to know what experimental expertise and equipment is available and how much it costs

Some key principles of Science Exchange ✔ ➡ Transparency ✔ ➡ Access ✔ ➡ Efficiency ✔ ➡ Reproducibility

Access You can access specialized expertise for pretty much any type of experiment: p roduc tj on of viruses for acquisition of tissue for ts ansduc tj on experiment s studies on clinical samples GENERATION OF STABLE CELL LINES generation of transgenic mice protein�production� conduction of animal studies including xenograft studies behavioral studies and neurological studies etc etc etc... Experiments benefit from the input of specialists

Access Science Exchange allows access to the wide range of experimental services offered by specialists in the research community

Some key principles of Science Exchange ✔ ➡ Transparency ✔ ➡ Access ✔ ➡ Efficiency ✔ ➡ Reproducibility

Efficiency ➡ the utilization of specialized experts rather than inefficient attempts to be jack-of-all-trades ➡ major efficiencies can be gained from specialization ➡ not having to buy specialized equipment ➡ not having to learn complicated one-off technique Many scientists believe it will be cheaper to do any experiment in own lab - this is not the case!

Efficiency B i l l f o r D I Y P C T R A p c l r o o d n i u n g c t o s f T O P O T A r c x l o n n ) . i . . n . g . . . k . . . i t . . ( . . 2 . 0 . . . . . . . . . vs. $31 . P . . . C . . $ R 4 6 ( 0 1 0 0 r x n ) . . . . . . . . . L . . . i . g . $ a s 7 e 8 ( 3 0 r x n ) . . . . . . . C . . . o . . . m . $ p 9 9 e t e n r t x c e n ) l l . s . . . ( . 1 . . 0 . . . . . . . . . . . . . . . . . . . . M . . i . $ n 2 i p 1 7 r e p k r i x t n ( ) 5 . per rxn . 0 . . . . . . . . . . . . . . . . . . . . . . . . R . . . e . . s . t $ r 8 i c 4 t i o n ( 1 e 0 n 0 z u y l m ) . e . . . . . . . . . . . . . . . . outsourced . . . . A . . . g . . a . $ r 5 o s 3 e g e l ( 5 0 g ) . . . E . . . t . . h $ 2 i d 6 i 5 u m b e t r c o m , e t i c d . e . . . e t c , e t c , T o t a l c o s t . . . . . . . . . . . . . . . $ T 1 , o 0 t 0 a l 0 ’ c s o s t ( p e r r x n . . ) . . . . . . . . . . . . . . . . . . . . . . . . . . . . $55 . . . . . .

Efficiency Science Exchange allows efficiencies to be gained from specialization

Some key principles of Science Exchange ✔ ➡ Transparency ✔ ➡ Access ✔ ➡ Efficiency ✔ ➡ Reproducibility

Reproducibility ➡ the cornerstone of scientific research ➡ independent rating system promotes high quality data ➡ replication of key data at multiple sites can eliminate non-reproducible data ➡ future requirement from funding agencies and publishers?

Reproducibility Science Exchange promotes reproducibility of research data

Let us know how we can help foster Open Science through Science Exchange? founders@scienceexchange.com