Crowdsourcing,Games,for, Biological,Research, Pravin,Muthu, - - PowerPoint PPT Presentation

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Oct 13, 2022 14 likes •301 views

Crowdsourcing,Games,for, Biological,Research, Pravin,Muthu, Emory,University, June,13,,2013, The,Kepler,Mission, Carter&Roberts& The,CiFzen,ScienFst, The,CiFzen,ScienFst, 18,894,075,ObservaFons,Analyzed, 34,PotenFal,Planets,Found,

SLIDE 1

Crowdsourcing,Games,for, Biological,Research,

Pravin,Muthu, Emory,University, June,13,,2013,

SLIDE 2

The,Kepler,Mission,

Carter&Roberts&

SLIDE 3

The,CiFzen,ScienFst,

SLIDE 4

The,CiFzen,ScienFst,

planethunters.org&

18,894,075,ObservaFons,Analyzed, 34,PotenFal,Planets,Found,

SLIDE 5

Crowdsourcing:,The,CollecFve,Expert,

SLIDE 6

LimitaFons,of,ComputaFonal,Methods,

SLIDE 7

LimitaFons,of,ComputaFonal,Methods,

SLIDE 8

Central,Dogma,

DNA, RNA, Protein,

SLIDE 9

PHYLO:,The,DNA,Puzzle,

SLIDE 10

Genome,Alignment,

SLIDE 11

Sequence,Alignments:,Computer,Approach, Y A E L A H Q H W G G R W L V Q L M K D T L L K W L M F L N L I K E K P K Y I L Y& 7& Q& 51& 5& F& 3& 53& 6& A& 52& 51& 52& 4& L& 51& 52& 0& 51& 4& Y& Q& F& A& L& Existence:&11&Extension:&1&&

SLIDE 12

Sequence,Alignments:,Computer,Approach, Y A E L A H Q H W G G R W L V Q L M K D T L L K W L M F L N L I K E K P K Y I L

SLIDE 13

Sequence,Alignment:,Human,Solved, Y A E L A H Q H W G G R W L V L Q L M K D T L L K W L M Y L N L I K E K P K Y I L

SLIDE 14

Phylo:,The,DNA,Puzzle,

SLIDE 15

EteRNA:,The,RNA,Puzzle,

SLIDE 16

The,RNA,World,

Ribosome, RNA, tRNA,

SLIDE 17

RNA,Modeling,

Ribosome, tRNA,

SLIDE 18

RNA,Modeling,

Ribosome, tRNA,

RNA,Modeling,

Mathis,et,al.,J.,Mol.,Biol.,(1999),288,,911±940,,

SLIDE 19

RNA,Folding,

SLIDE 20

RNA,Folding,

SLIDE 21

Let’s,Play,EteRNA!,

SLIDE 22

Foldit:,The,DNA,Puzzle,

SLIDE 23

Protein,Modeling,

SLIDE 24

Protein,Modeling,

SLIDE 25

Research,Example,

SLIDE 26

Let’s,Play,Foldit!,

SLIDE 27

Final,Thoughts, Games& GamificaHon&

Andrzej,Marczewski,

SimulaHons& Gameful&Design&

Purpose& Fun& Gameplay& No&Gameplay&

SLIDE 28