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Common complications in the late preterm infant Tamara Kerbelker Talk overview Definitions Epidemiology Short term complications Long term complications Prevention Recommendations for outpatient management Definitions


  1. Common complications in the late preterm infant Tamara Kerbelker

  2. Talk overview  Definitions  Epidemiology  Short term complications  Long term complications  Prevention  Recommendations for outpatient management

  3. Definitions  Prematurity  Birth before 37 completed weeks

  4. Classification according to gestational age  Late preterm birth – GA between 34 and less than 37 weeks  Very preterm (VPT) birth – GA less than 32 weeks  Extremely preterm (EPT) birth – GA at or below 28 weeks

  5. Classification according to birth weight  Low birth weight (LBW) – Birth weight less than 2500 g  Very low birth weight (VLBW) – Birth weight 1000-1499g  Extreme low birth weight (ELBW) – birth weight <999g

  6. Epidemiology Western Cape PPIP data 2016

  7. Epidemiology Western Cape PPIP data 2016

  8. Short term complications  Hypothermia  Respiratory distress syndrome  Apnoeas of prematurity  Patent ductus arteriosus  Hypotension  Intraventricular haemorrhage  Glucose anomalies  Infection  Retinopathy of Prematurity

  9. Hypothermia  Rapid heat loss  large body surface area  inability to produce enough heat  Heat is lost by conduction, convection, radiation, and evaporation  Contributes to metabolic disorders - hypoglycaemia or acidosis.  Increased mortality  Intraventricular haemorrhage (IVH),pulmonary insufficiency, haemorrhage

  10. Prevention of hypothermia  Drying the baby thoroughly immediately after birth  Removal of any wet blankets  Plastic bags  Kangaroo mother care (KMC) – skin-to-skin

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  12. Respiratory distress syndrome  Surfactant deficiency  Early CPAP

  13. Apnoeas of prematurity  More common in the patients with lower gestational age  Stimulation  Helping Babies Breathe (HBB)

  14. Glucose anomalies  Keep warm  Feed early

  15. Interventions to improve short term 15 complications and outcome  Helping Babies Breathe (HBB)  Management of the sick and small newborn (MSSN)  CPAP to all district facilities

  16. Long term complications 18

  17. Long term complications  Recurrent hospitalisation  Increased risk of SIDS  Neurodevelopmental outcomes  Chronic health conditions  Growth impairment  Impaired lung function  Effect on adult health

  18. Recurrent hospitalisation  Respiratory  RSV (any viral infection)  Asthma  Gastrointestinal  GORD  Gastroenteritis

  19. Prevention of recurrent hospitalisation  Promote breastfeeding  Ensure vaccinations  Influenza vaccine  No tobacco smoke exposure  Vitamin A supplementation  Limit contact with sick people  Limit crowded environments (if possible) – malls, taxis  RSV immunoglobulin

  20. Growth impairment  Lower weight for age  Lower height for age  Lower BMI  Smaller head circumference

  21. Growth impairment 23  Plot the child at every visit  Head circumference  Height  Weight  Weight for height  Supplemental iron  Multivitamins  Vit D  Wean at 6 months

  22. Neurodevelopmental outcomes  Impaired cognitive skills  Motor deficits including mild fine or gross motor delay, and cerebral palsy (CP)  Sensory impairment including vision and hearing losses  Behavioural and psychological problems

  23. Neurodevelopmental outcomes Infant neurological assessment (INA)  Neurodevelopmental paediatrician  or general paediatrician School placement  ADHD management  Sensory screening  Vision  Hearing  Allied health  Physiotherapy  Occupational therapy  Speech therapy  Educational psychologist 

  24. Chronic health conditions  Cerebral palsy  Cognitive deficit  Asthma  Decreased exercise capacity  Increased respiratory symptoms  Chronic kidney disease  Smaller kidneys  Higher blood pressure  Microalbuminuria

  25. Effect on adult health  Insulin resistance  Hypertension  Lower reproduction rate

  26. Primary prevention Prevent the pregnancy  Female empowerment  Contraception  Planned pregnancy  Teenage pregnancy

  27. Other prevention 29  Educate expecting moms BANC sites and the importance of antenatal care  Maternal nutrition  Treatment of STIs, TB  HIV testing and prevention during pregnancy  Alcohol and drug use during pregnancy

  28. What can we do 30  Supplements at discharge  Encourage any breastfeeding  Educate moms on basic life support  Educate moms about risk factors for SIDS  Apnoea monitors  Synagis motivation  Vigilance with any ARI  Encourage immunisation  Follow up visits  Monitor growth and development  Facilitate allied health visits

  29. 31 Questions? 2017-08-08

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