Bioinformatics: Network Analysis Networks in Biology COMP 572 (BIOS - - PowerPoint PPT Presentation

bioinformatics network analysis
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Bioinformatics: Network Analysis Networks in Biology COMP 572 (BIOS - - PowerPoint PPT Presentation

Bioinformatics: Network Analysis Networks in Biology COMP 572 (BIOS 572 / BIOE 564) - Fall 2013 Luay Nakhleh, Rice University 1 T ranscriptional Networks Systems of transcription factors (TFs) and their target genes [Source: Wikimedia] 2


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SLIDE 1

Bioinformatics: Network Analysis

Networks in Biology

COMP 572 (BIOS 572 / BIOE 564) - Fall 2013 Luay Nakhleh, Rice University

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SLIDE 2

T ranscriptional Networks

Systems of transcription factors (TFs) and their target genes

[Source: Wikimedia]

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SLIDE 3

Signaling Networks

Systems of signaling proteins and their interactions

[Source: Wikimedia]

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SLIDE 4

Metabolic Networks

Systems of chemical reactions that convert nutrients into cellular materials or use them to provide energy

[Source: Wikimedia]

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SLIDE 5

Protein Interaction Networks

Systems of proteins and their interactions

[Source: Barabasi et al., 2004]

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SLIDE 6

Neuronal Networks

Systems of neurons and their interactions

[Source: neuralwiki.blogpost.com]

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SLIDE 7

Ecological Networks

[Source: Wikimedia]

Systems of organisms and their interactions

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SLIDE 8

Phylogenetic Networks

Reticulate evolutionary histories

[Source: Teshima and Innan, 2012]

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SLIDE 9

Social Interaction Networks

Systems of individuals and their interactions

[Source: Christakis and Fowler, 2007]

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SLIDE 10

Keep In Mind

✤ A network can represent any system of entities where pairwise

relationships can be established...

✤ The network representation lends the system to a wide array of

network-oriented analytical and visualization tools.

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