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Nov 14, 2023 153 likes •276 views

ASSOCIATION OF MERCURY EXPOSURE WITH PERCEIVED HEALTH AND HEALTH-RELATED QUALITY OF LIFE DURING PREGNANCY IN SURINAME A . R . G O K O E L , L . L . K A E R S E N H O U T , A . D . H I N D O R I - M O H A N G O O , M . S . M A C D O N A L

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A . R . G O K O E L , L . L . K A E R S E N H O U T , A . D . H I N D O R I - M O H A N G O O , M . S . M A C D O N A L D - O T T E V A N G E R , C . W . R . Z I J L M A N S , M . Y . L I C H T V E L D , E . W . H A R V I L L E

ASSOCIATION OF MERCURY EXPOSURE WITH PERCEIVED HEALTH AND HEALTH-RELATED QUALITY OF LIFE DURING PREGNANCY IN SURINAME

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DISCLAIMER

This work is supported by the NIH Fogarty International Center (grant numbers R24TW009570, R24TW009561, U01TW010087, and U2RTW010104)

The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health

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BACKGROUND

Mercury exposure (during pregnancy)may cause adverse health

effects in women and children e.g. adverse neuro-developmental disorders for the child

The abundant use of mercury in illegal gold mining in Suriname’s

interior is of growing concern

This study examined the association between hair Hg levels and,

perceived health and Health-Related Quality of Life (HRQoL) in Surinamese pregnant women

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METHODS

Epidemiologic environmental cohort study
Standardized questionnaire: SF-36 (HRQoL, score 0-100)
HRQoL: physical functioning, role-physical, bodily pain, vitality, general

health, role emotional and mental health

Perceived health: 5- point likert scale
Hair mercury: < 1.1 ug/g, ≧1.1 ug/g (U.S. EPA action level)
n= 311 pregnant women

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DISTRIBUTION OF HAIR HG LEVELS AND PERCEIVED HEALTH

228 (73.3%) 83 (26.7%)

50 100 150 200 250

< 1.1 ≥ 1.1 n Hg levels 95 (27.5%) 250 (72.5%)

50 100 150 200 250 300

poor, fair good, very good, excellent

n perceived health

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ASSOCIATION SOCIO-DEMOGRAPHICS AND PERCEIVED HEALTH

Perceived health Bivariate OR (95% CI) p-value Good, very good, excellent n (%) Poor, fair n (%) Age 0.32 <20 years 18 (64.3) 10 (35.7) 1.51 (0.67-0.42) ≥20 years 207 (73.1) 76 (26.9) 1 Ethnic group 0.81 African descent 97 (70.8) 40 (29.2) 1 Asian descent 79 (74.5) 27 (25.5) 0.83 (0.47-1.47) Other 49 (72.1) 19 (27.9) 0.94 (0.49-1.79) Region 0.06 Interior 4 (44.4) 5 (55.6) 3.41 (0.89-13.01) Other 221 (73.2) 81 (26.8) 1 Education 0.05 ≤ secondary 180 (70.0) 77 (30.0) 2.14 (0.95-4.08) higher 45 (83.3) 9 (16.7) 1 Household income 0.54 <3000 120 (71.9) 47 (28.1) 1.19 (0.69-2.06) ≥ 3000 82 (75.2) 27 (24.8) 1

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DISTRIBUTION OF PERCEIVED HEALTH FOR NORMAL AND ELEVATED HAIR HG LEVELS

p= 0.40

162 (71.1%) 63 (75.9%) 66 (28.9%) 20 (24.1%)

50 100 150 200 250

< 1.1 ≥ 1.1

poor, fair good, very good, excellent

Perceived health

(Hg)

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DISTRIBUTION OF HRQOL AMONG PREGNANT WOMEN FOR NORMAL AND ELEVATED HAIR HG LEVELS

77.0 57.0 65.0 50.4 65.5 66.2 68.5 77.8 60.0 68.0 49.6 67.3 69.5 67.8 physical functioning role physical bodily pain vitality general health role emotional mental health < 1.1 ≥ 1.1 (Hg)

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CONCLUSION

1 out of 4 pregnant Surinamese women had hair Hg levels above the

USEPA action level

Hair Hg was not significantly associated with lower HRQoL and poor

perceived health

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DISCUSSION & ASSUMPTIONS

Results are preliminary and may change as the study progresses
Further research is mandated to determine the association between