antimicrobial resistance
play

Antimicrobial Resistance: A global public health threat Dr Mark Schipp Australian Chief Veterinary Officer Rotary WA May 2019 1 A very quick introduction What is AMR? - When micro-organisms evolve resistance to antimicrobial substances,

0 downloads 5 Views 1,34 MB Size Report
  1. Antimicrobial Resistance: A global public health threat Dr Mark Schipp Australian Chief Veterinary Officer Rotary – WA May 2019 1

  2. A very quick introduction What is AMR? - When micro-organisms evolve resistance to antimicrobial substances, like antibiotics. Why is AMR important? - AMR threatens the effective prevention and treatment of an ever-increasing range of infections. - An increasingly serious threat to global public health that requires action across all government sectors and society. 2

  3. Nature of the problem • AMR is an increasing health concern in Australia and around the world. • If not addressed, simple infections could cause significant harm. • It is estimated that by 2050, ten million people will die every year as a result of AMR. • Even today, 700,000 people die of resistant infections every year. 3

  4. Why do we have a problem?

  5. Why is a vet speaking to us? • Most antibiotics are used in animal industries • AMR may be transmitted through food • A One Health issue One Health recognises the • interconnectedness of human, animal and environmental health. https://www.canada.ca/en/health-canada/services/ publications/drugs-health-products/tackling- antimicrobial-resistance-use-pan-canadian- framework-action.html 5

  6. Antimicrobial use in Australia Reference adapted from: Reference: http://amr-review.org/sites/default/files/Antimicrobials%20in%20agriculture%20and%20the%20environment%20- http://www.safetyandquality.gov.au/wp-content/uploads/2016/06/AURA-2016-First-Australian-Report-on- %20Reducing%20unnecessary%20use%20and%20waste.pdf Antimicroibal-use-and-resistance-in-human-health.pdf

  7. Antibiotic use in Australia • Australians are over-using antibiotics in human health. • Australia is the 11 th highest user of antibiotics out of 31 OECD countries. • In 2015, more than 30 million antibiotic scripts were provided through the Pharmaceutical Benefits Scheme. 7

  8. What is being done? National AMR Strategy Key objectives : 1. Communication, education and training 2. Antimicrobial Stewardship 3. Surveillance 4. Infection prevention and control 5. Research and development 6. International engagement 7. Governance 8

  9. Animal health key initiatives Best practice antibiotic prescribing guidelines – pigs § Veterinary antimicrobial stewardship online training program § Antimicrobial growth promotants (AGPs) – no label claims § OIE antimicrobial usage (AMU) annual questionnaire § Antibiotic Awareness Week § ASTAG Antibacterial list working group § Compendium report on antimicrobial stewardship efforts – livestock industries § Antimicrobial Stewardship Guidelines for the Australian Cattle Feedlot Industry § Factsheets on responsible antibiotic use – companion animals, livestock and horses § There are currently only three antibiotics registered with growth promotant claims, none of § which are currently important for human medicine

  10. How are things in Australia? ü An excellent animal health status ü Australia already has a regulatory ü A best practice animal identification system working to minimise AMR and traceability system ü Australia has been very ü We have good partnerships between conservative in registering industry and government antibiotics for use in food ü Our systems are flexible and animals. responsive ü Nearly all antimicrobials used in ü We have good agricultural practices animals are Schedule 4 including on-farm hygiene and medicines. biosecurity ü Our feedlot industry are the first ü Many of our industries implement anywhere in the world to implement biosecurity manuals and QA systems a stewardship program, and how to ü Australian veterinarians have been use antimicrobials appropriately. proactively mitigating AMR for some ü Opportunities for Australia time. 10

  11. Is food a risk? In Australia we have surveyed animals: ü Cattle (2013) – (Note: beef cattle, dairy cattle and veal calf) ü Pigs (2018) ü Chicken meat (2018) ü Chicken Eggs (2018) o Salmon o Barramundi o Chicken Egg – further work ? Others (Note: This relates to samples from healthy animals.) 11

  12. What about imported food? Sourcing Certification Testing Disease status Cooked Processed Genetic material Residue testing Reference: https://www.spok.com/blog/ swiss-cheese-model-patient- safety-errors-closing-holes- message-accountability

  13. Future Vision Ø Coordination – government/industry, One Health, internationally Ø Surveillance – human/animal/food/environment, use, resistance Ø Key data systems – Antimicrobials used, laboratory results, standardised, integrated Ø Resourced – community awareness, research, preventive

  14. Summary • A time for action • Opportunities for the future $$ • More work needed Reference: http://www.oie.int/en/for-the-media/amr/ waaw2015/

Recommend Documents


antimicrobial resistance
Antimicrobial Resistance Rob Doyle

In-Feed Medication and Antimicrobial Resistance Rob Doyle SSVI

outline
Outline Antimicrobial Resistance

26/10/2016 Antimicrobial Stewardship and Current Issues in Infection

the evolution of acquired antimicrobial resistance in
THE EVOLUTION OF ACQUIRED ANTIMICROBIAL

THE EVOLUTION OF ACQUIRED ANTIMICROBIAL RESISTANCE IN EUROPE AND IN THE

antibiotic resistance
Antibiotic Resistance Xenia Bray

Infection Control and Antibiotic Resistance Xenia Bray Learning Objectives

antimicrobial resistance and strategies for gram negative
Antimicrobial resistance and strategies

Antimicrobial resistance and strategies for Gram-negative bacteria Y

bactiguard
Bactiguard Q2 presentation August 10,

1 Bactiguard Q2 presentation August 10, 2017 2 Infections and

status quo and current challenges related
Status quo and current challenges

Status quo and current challenges related to antimicrobial resistance:

antimicrobial stewardship
ANTIMICROBIAL STEWARDSHIP Introduce

06/08/2020 Session Outcomes Discuss the origins of bacteria, antibiotics and

antimicrobial resistance a global problem the
Antimicrobial resistance: a global

Antimicrobial resistance: a global problem The connectivity of potential

antimicrobial peptides
Antimicrobial peptides Drug Processing

Formulation of Antimicrobial peptides Drug Processing and Delivery,

intervention for hospitals
intervention for hospitals. NIHR

Development and evaluation of a complex ePrescribing-based Antimicrobial

antibiotic stewardship and the role of improved diagnosis
Antibiotic stewardship and the role of

Antibiotic stewardship and the role of improved diagnosis in the management

antimicrobial stewardship response to a global crisis
Antimicrobial Stewardship: Response to

Antimicrobial Stewardship: Response to a Global Crisis Carla Walraven,

preventing and treating chronic infections softox
Preventing and treating chronic

Preventing and treating chronic infections SoftOx Solutions AS A Norwegian

role of pharmacodynamics in antimicrobial therapy
Role of Pharmacodynamics in

Role of Pharmacodynamics in Antimicrobial Therapy G.L. Drusano, M.D.

antimicrobial stewardship
Antimicrobial Stewardship JONATHAN

9/21/2017 Antimicrobial Stewardship JONATHAN PERDUE, PHARMD PGY1 PHARMACY

covid 19
COVID-19 HCPF Office of Community

COVID-19 HCPF Office of Community Living Presented by: Kim Bimestefer, Julie

antimicrobial therapy for uncomplicated cystitis in the
ANTIMICROBIAL THERAPY FOR

ANTIMICROBIAL THERAPY FOR UNCOMPLICATED CYSTITIS IN THE EMERGENCY DEPARTMENT

antibacterial activity antibacterial activity standard
ANTIBACTERIAL ACTIVITY Antibacterial

Graphical Presentation of Antimicrobial Activity ANTIBACTERIAL ACTIVITY

fighting infections and antimicrobial resistance through
Fighting Infections and Antimicrobial

Fighting Infections and Antimicrobial Resistance Through GPU-Accelerated In

presentation guide simple steps
Presentation Guide Simple Steps o

Presentation Guide Simple Steps o Understand your product o What problem is