Amyris, Inc. H.C. WAINWRIGHT 22ND ANNUAL GLOBAL INVESTMENT - PowerPoint PPT Presentation

Amyris, Inc. H.C. WAINWRIGHT 22ND ANNUAL GLOBAL INVESTMENT CONFERENCE September 14, 2020

H.C. Wainwright Investor Conference | September 14, 2020 FORWARD LOOKING STATEMENT This presentation and oral statements accompanying this presentation contain forward-looking statements, and any statements other than statements of historical fact could be deemed to be forward-looking statements. These forward-looking statements include, among other things, statements regarding future events, such as expected revenue, including revenues from consumer, ingredients, collaboration & grants, recurring revenue, EBITDA, gross profit, gross margin and operating expenses in 2020, including related growth rates, anticipated growth for Amyris’s businesses, expected debt reduction in 2020, and expectations regarding Amyris’s financial and operational results and ability to achieve its business plan in 2020 and beyond. These statements are based on management’s current expectations and actual results and future events may differ materially due to risks and uncertainties, including risks related to Amyris’s liquidity and ability to fund operating and capital expenses, risks related to potential delays or failures in development, production or commercialization of products, risks related to Amyris's reliance on third parties, and other risks detailed from time to time in filings Amyris makes with the Securities and Exchange Commission, including Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q and Current Reports on Form 8-K. Amyris disclaims any obligation to update information contained in these forward-looking statements, whether as a result of new information, future events, or otherwise. NON-GAAP FINANCIAL INFORMATION This presentation and oral statements accompanying this presentation contain both GAAP and non-GAAP financial information. Amyris considers non-GAAP financial information to be a helpful measure to assess its operational performance and for financial and operational decision-making. Totals in this presentation may not foot due to rounding.

H.C. Wainwright Investor Conference | September 14, 2020 Amyris is Delivering Clean Chemistry for a Healthier Planet A track record of industry leading growth driven by consumer megatrends and enabled by proprietary science • Leading synthetic biology portfolio of platform FY 2018-2019 Sales molecules driving speed to market and enabling deep $180 ($ in millions) disruption in the health, beauty & wellness markets +140% $160 $140 $120 $100 • ESG-driven high growth Clean Beauty consumer $80 153 $60 brands disrupting the beauty space $40 64 $20 $0 FY 2018 FY 2019 • Proprietary functional sustainable natural ingredients 56% for flavors and fragrance, and health and wellness end- markets 2019 GROSS MARGIN (NON-GAAP) Page 3

H.C. Wainwright Investor Conference | September 14, 2020 Synthetic Biology Enabling Growth in Sustainable and Clean Brands The #1 Supplier of Clean, Sustainable ingredients World’s leading synthetic biology platform to Leading Brands The world’s leading synthetic biology platform. Nine commercialized products delivering the most profitable and fastest growing revenue in synthetic biology High growth Clean Beauty consumer brands Our Biossance & Pipette Clean Skin Care brands are the fastest growing in North America with revenue doubling YOY Proprietary functional natural & sustainable ingredients Our ingredients are inside over $10B of consumer purchases sold through 3,000+ of the world’s leading brands with revenue growing 60-80% YOY Owner of the Leading Clean Health and Beauty Clean and safe natural ingredients are more important than ever before Brands in North America Consumers are transitioning to clean and safe ingredients faster than ever and we are a leading supplier with advantaged technology Page 4

H.C. Wainwright Investor Conference | September 14, 2020 Amyris’ Technology Accelerating Key Technical Metrics Molecules commercialized per year ~2-4 Industry Disruption Number of PhD’s ~85 Number of US and foreign patents 871 issued and applications pending Addressable Market Molecules Manufactured 10 Growth markets that are accelerated Pipeline of molecules in development 17 by Consumers push for Health, 9 Clean and Sustainable 48 From First Strain to First Pilot Run (2012-2019 ) • Clean Beauty to become the standard in beauty $Billion 200 • Natural flavors and fragrances is the clear direction • Alternative sweetener with great taste and mouthfeel is redefining the sugar reduction experience for Beauty (Skin Care + Baby) the worlds leading consumer brands Flavors & Fragrance Alternative Sweeteners Page 5

H.C. Wainwright Investor Conference | September 14, 2020 Growing In Attractive Markets With Clean Sustainable Products High growth wholly owned consumer brands Clean skincare Baby & Mothercare Alternative Sweetener Pipette TM Purecane TM Biossance TM Functional natural ingredients delivering performance and sustainability Flavors & Alternative Clean Beauty for 1 Based on 2020 estimate Fragrance for Sweetener for Cosmetics Home and Food & Beverage Personal Care Page 6

H.C. Wainwright Investor Conference | September 14, 2020 A Track Record of Industry Leading Growth Q4 2020 Revenue growth driven by consumer holiday purchases and new ingredients Consumer Revenue $m Ingredients Revenue $m Excl. One-off $50 0.25 $50 0.25 $45 $45 $40 0.2 $40 0.2 ~250% CAGR ~50% CAGR 2016-2020 2016-2020 $35 $35 $30 0.15 $30 0.15 $25 $25 $20 0.1 $20 0.1 $15 $15 $10 0.05 $10 0.05 16 14 13 13 10 10 9 9 8 $5 $5 7 7 5 4 4 4 3 3 3 2 1 $0 0 $0 0 Q118 Q218 Q318 Q418 Q119 Q219 Q319 Q419 Q120 Q220 Q320F Q420F Q118 Q218 Q318 Q418 Q119 Q219 Q319 Q419 Q120 Q220 Q320F Q420F Consumer Sales Revenue ($m) Ingredients Sales Revenue ($m) excl one-offs Sales Revenue Summary Actual Actual USD Millions Q118A Q218A Q318A Q418A FY18A Q119A Q219A Q319A Q419A FY19A Q120A Q220A Product excl One-off items 5.2 6.6 9.8 12.2 33.9 12.4 12.4 19.7 20.4 64.9 19.3 26.2 One-off items 7.9 (0.5) - - 7.4 (0.4) 40.7 - 8.8 49.1 3.8 - Product as reported 13.2 6.1 9.8 12.2 41.3 12.0 53.1 19.7 29.2 113.9 23.0 26.2 Page 7

H.C. Wainwright Investor Conference | September 14, 2020 Consumer Brand Scorecard – Clean Brand Leadership Strong portfolio and pipeline that is expected to double revenue next few years H1 2020 vs H1 2019 750K - 1M Performance Sold 3.6M units to monthly consumer 750K customers website visits Consumer revenue = 3X Consumer website visits = 3X 28K 5 stars 550K Instagram product ratings followers Online revenue = 6X out of 33K total Page 8

H.C. Wainwright Investor Conference | September 14, 2020 2020 BIOSSANCE IS LEADING THE WAY • Products consumers love • Setting the standard for Clean Beauty • More than doubling revenue year over year • Industry leading Return On Advertising Spend Return on Advertising Spend: Q3 2019: $3.76 Q4 2019: $5.43 Q1 2020: $7.62 Q2 2020: $11.11 Page 9

H.C. Wainwright Investor Conference | September 14, 2020 Investor Presentation | May 2020 Launched September 4, 2019 • EWG Verified™ Retail Channel Distribution • Leaping Bunny Approved • Dermatologist tested • Pediatrician approved • Hypoallergenic • Nontoxic • Vegan • Synthetic fragrance-free Page 10

H.C. Wainwright Investor Conference | September 14, 2020 Pipette Has A Full Offering For Baby, Mom And The Entire Family Brought new Pipette Brought new Pipette branded hand sanitizer to branded hand sanitizer to market in April in 10 days market in April in 10 days Page 11

H.C. Wainwright Investor Conference | September 14, 2020 Formula For Profitable Growth High growth wholly owned Functional natural ingredients consumer brands • Revenue doubling YOY • Revenue growing at 60-80% YOY • 60-70% gross margin • 45-50% gross margin at scale 1 • Marketing expense to educate consumers, • Minimal direct go-to-market expense support and grow brands • $70M capital expenditure for every $200M of • No capital expenditure requirement annual revenue • ~30% EBITDA margin at scale • ~35-40% EBITDA margin 1 Excludes scale-up expense and reflects benefit of new Brazil integrated plant to be commissioned by end of 2021 Page 12

H.C. Wainwright Investor Conference | September 14, 2020 H1 2020 Margin Economics Ingredients margins to enhance once new Brazil integrated plant is commissioned end of 2021 High growth wholly owned Functional natural ingredients consumer brands Gross Margin as % of Sales Revenue Gross Margin as % of Sales Revenue excl one-off $70 0.25 +1,000 $70 0.25 $60 bps 0.2 $60 0.2 $50 $50 63% 0.15 $40 0.15 $40 $30 38% 0.1 $30 0.1 $20 $20 7% 0.05 0.05 $10 $10 $0 0 $0 0 Total Biossance Pipette Purecane Total Excl Scale-up Pro forma expense integrated plant Page 13