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Alopecia areata Lidia Rudnicka Department of Dermatology, Medical - PowerPoint PPT Presentation

Apr 07, 2024 •211 likes •481 views

Alopecia areata Lidia Rudnicka Department of Dermatology, Medical University of Warsaw Poland lidiarudnicka@gmail.com I have no relevant conflicts of interest anagen phase Hair cycle telogen phase catagen phase anagen effluvium Anagen

  1. Alopecia areata Lidia Rudnicka Department of Dermatology, Medical University of Warsaw Poland lidiarudnicka@gmail.com I have no relevant conflicts of interest

  2. anagen phase Hair cycle telogen phase catagen phase

  3. anagen effluvium Anagen effluvium occurs after any insult to the hair follicle that impairs its mitotic activity . Causes: Inflammatory (alopecia areata) Drug-induced (chemotherapy, retinoids) Toxic (thallium, arsenic) Extreme nutrient deficiencies

  4. High mitotic activity - thick hair Low mitotic activity - thin hair No mitotic activity - no hair

  5. • Common trichoscopy features of AA • Rare trichoscopy features of AA • Trichoscopic cases in AA

  6. Alopecia areata in trichoscopy Exclamation mark hairs Black dots Yellow dots

  7. Multiple exclamation mark hairs = high disease activity

  8. Alopecia areata – tapered hairs Tapered hairs are elongated exclamation mark hairs Inui et al. 2009

  9. Pohl-Pinkus constrictions and monilethrix-like hairs in alopecia areata These hairs differ from true monilethrix by the irregular distribution of constrictions

  10. Alopecia areata – black dots

  11. black dots a marker of high disease activity in alopecia areata but not specific for alopecia areata

  12. Alopecia areata – yellow dots

  13. Yellow dots may not be visible in Asian patients S. Inui . Trichoscopy in Asian Skin in Atlas of Trichoscopy, 2012

  15. • Common trichoscopy features of AA • Rare trichoscopy features of AA • Trichoscopic cases in AA

  16. Alopecia areata – vellus hairs Asian Caucasian Marker of disease severity ? Inui et al

  17. • Trichorrhexis nodosa • Zigzag hairs

  18. Zigzag hairs

  19. Alopecia areata – regrowing hairs 70x circle pigtail

  21. Trichoscopy feature % of patients with AA Yellow dots 63-94% Black dots 44-70% Exclamation mark hairs 30-44% Tapered hairs 12-42% Broken hairs 45-58% Vellus hairs 33-72% Trichorrhexis nodosa 3-16% Monilethrix-like hairs 2-3% Pohl-Pinkus constrictions Regrowing hairs Source: Atlas of Trichoscopy, 2012

  22. • Common trichoscopy features of AA • Rare trichoscopy features of AA • Trichoscopic cases in AA

  24. 43 – year old woman Chemotherapy – induced alopecia

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