AI in Integrative Health Shaista Malik, MD, PhD, MPH Professor, - - PowerPoint PPT Presentation
AI in Integrative Health Shaista Malik, MD, PhD, MPH Professor, Department of Medicine Executive Director, Susan Samueli Integrative Health Institute Associate Vice Chancellor, Integrative Health Integrative Health Conventional Health Care
Shaista Malik, MD, PhD, MPH Professor, Department of Medicine Executive Director, Susan Samueli Integrative Health Institute Associate Vice Chancellor, Integrative Health
Conventional Health Care Lifestyle Medicine (Self Care) Complementary & Alternative Medicine
ORGAN SYSTEM DIAGNOSIS ANTECEDENTS, TRIGGERS AND MEDIATORS
INTEGRATIVE PILLARS OF HEALTH AND WELLNESS
Integrative Health and Personalized Medicine: Layers of Data for an Individual
Topol et al, Cell 2014 Individualized Medicine from PreWomb to Tomb, Geographic Information System
The P4H continuum model.
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The P4 Health Spectrum – A Predictive, Preventive, Personalized and Participatory Continuum for Promoting Healthspan Sagner, Michael; et al.Progress in Preventive Medicine2(1):e0002, January 2017.
Comprehensive History and Physical Nutrition and Lifestyle Stress & Relationships Advanced Biomarkers Genomics Environmental Exposure Subclinical Disease Imaging
Integrative Medicine: Assessment
Advanced Biomarkers
48 year old male with elevated CAC (95th percentile), on high- intensity statin (Crestor 20 mg) LDL 72 Evidence of Residual Risk Inflammatory markers Prediabetes (A1c 5.8, Fasting Insulin 17)
Advanced Biomarkers Cardiovascular Genomics
J Cell Mol Med. 2008, 12(6b): 2762-2771
Weights are generally assigned to each genetic variant according to the strength of their association with disease risk (effect estimate). Individuals are scored based on how many risk alleles they have for each variant (for example, zero, one, or two copies) included in the polygenic score
Optimal Medical Management Advanced biomarker testing, guidance for Nutriceutical Therapies Addressing actionable genetic variations
Nutrition and Lifestyle Prescriptions Mind-Body Interventions
Meditation
Addressing Toxin ovrerload
Treatment of Subclinical or Microvascular Disease