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A Nuclear Services and Waste Management Company Investor Presentation March 2017 Nasdaq: PESI NASDAQ: PESI Safe Harbor Certain statements contained within this presentation may be deemed forward - looking statements within the


  1. A Nuclear Services and Waste Management Company Investor Presentation – March 2017 Nasdaq: PESI

  2. NASDAQ: PESI Safe Harbor • Certain statements contained within this presentation may be deemed “forward - looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended (collectively, the “Private Securities Litigation Reform Act of 1995"). All statements in this presentation other than a statement of historical fact are forward-looking statements that are subject to known and unknown risks, uncertainties and other factors which could cause actual results and performance of the Company to differ materially from such statements. The words “believe,” “expect,” “anticipate,” “intend,” “will,” and similar expressions identify forward -looking statements. Forward-looking statements contained herein relate to, among other things, – the Company’s ability to develop or adopt new and existing technologies; – anticipated financial performance; – growth through acquisition; – leader in the mixed waste industry; – positioned to benefit from mixed waste market opportunities; – geographic strongholds; and – all other statements which are not statements of historical fact. • While the Company believes the expectations reflected in such forward-looking statements are reasonable, it can give no assurance such expectations will prove to have been correct. There are a variety of factors which could cause future outcomes to differ materially from those described in this report, including, but not limited to: – general economic conditions; – increased competitive pressures; – the ability to maintain and obtain required permits and approvals to conduct operations; – the ability to develop new and existing technologies in the conduct of operations; – changes in federal, state and local laws and regulations, especially environmental regulations, or in interpretation of such; and – the commercial viability of our on-site treatment process. 2

  3. NASDAQ: PESI Company Overview Leveraging core assets to become a leader in the nuclear industry. Medical Treatment Services 3

  4. Nuclear 4

  5. NASDAQ: PESI Nuclear Treatment Facilities Three unique and irreplaceable facilities DSSI - Kingston, TN Perma-Fix North West - Richland, WA Perma-Fix Florida - Gainesville, FL 5

  6. NASDAQ: PESI Waste Treatment • Perma-Fix is a leading provider of nuclear waste treatment services – Perma-Fix specializes in treating nuclear wastes – Waste generated by commercial customers, utilities, hospitals, research facilities, and the government • DOE is the largest generator of nuclear waste – Legacy waste dating back to Manhattan Project – Massive quantities accumulated during Cold-War – Federal, state and local communities mandate for the treatment of this waste • Strong and long-standing relationships with key government agencies including DOE, NRC, and NNSA 6 6

  7. NASDAQ: PESI Primary Markets - Nuclear • Department of Energy – Over 1000 legacy nuclear excess facilities – $17B budget (EM and NNSA) • Department of Defense – Base realignment and closure – Threat reduction – FUSRAP • Commercial Nuclear – 104 in the United States – 423 worldwide – Increase by 90-230 new reactors by 2020 • International – Global nuclear waste and service markets in N. America, Europe, & Asia 7

  8. NASDAQ: PESI Massive Barriers to Entry • Highly regulated at State and Federal levels – Nuclear Regulatory Commission through State regulators – Environmental Protection Agency through State regulators – State Regulators for other air and water permits • Technology – Patented and proprietary chemical treatment process – Treatment of nuclear waste is complex and requires multiple technologies and multiple steps • Experience – Unparalleled experience and track record of facilities successfully treating nuclear waste 30+ years 8

  9. NASDAQ: PESI Nuclear Services • Services group provides waste personnel and capabilities on client’s sites for a variety of industrial and government clients – Major contracts with Department of Energy facilities – Expansion into commercial and international helping diversify revenue • Capabilities include health physics and remediation of nuclear materials for the DOE, DOD, federal agencies and commercial customers, including: – FEMA – Army Corps of Engineers – Bechtel Companies – UK Government Today, under the direction of the U.S. DOE, Hanford is engaged in the world's largest environmental cleanup project; Expected to continue until 2030 and cost over $100 billion 9

  10. NASDAQ: PESI Financial Results $140,000 $127,509 $118,610 $120,000 $97,790 $100,000 $92,393 $74,413 $80,000 $64,553 $62,383 $57,065 $60,000 $40,000 $16,500 $20,000 $13,799 $10,749 $5,029 $3,349 $6,975 $(1,252) $3,719 $- 2008 2009 2010 2011 2012 2013 2014 2015 $(20,000) Revenue Adj. EBITDA Return to growth & profitability; achieved adjusted EBITDA* of $7M for FY 2015 *Adjusted EBITDA is defined as EBITDA before R&D costs related to the Medical Isotope project in 2014, and impairment loss on goodwill and cost in excess of revenue and amortization of acquired contracts in the applicable periods. 10

  11. NASDAQ: PESI Q3 2016 Financial Results & Guidance • Revenue for the third quarter of 2016 was $12.9 million versus $17.3 million for the same period last year – Revenue for the Treatment Segment was $7.6 million compared to $10.9 million for the same period in 2015 due to lower waste volume – Revenue from the Services Segment was $5.3 million versus $6.4 million for the same period in 2015 • Achieved Adjusted EBITDA $152,000 despite continued delays of waste shipments within the Treatment Segment • Anticipate improvement in revenue and cash flow in Q4 and 2017 as waste that was delayed has begun to ship • Continue to look at all aspects of the business from a cost standpoint – Proceeding with the planned shutdown of M&EC facility, which should save an estimated $2 to $3 million annually – Currently anticipate adjusted EBITDA for Q4 2016 of $1M million *Adjusted EBITDA is defined as EBITDA before R&D costs related to the Medical Isotope project in 2014, and impairment loss on goodwill and cost in excess of revenue and amortization of acquired contracts in the applicable periods. 11

  12. Perma-Fix Medical S.A. (PFM) 12

  13. WSE: PFM Business Summary Disruptive technology to produce the most commonly used medical isotope in the world – Technetium-99m (Tc-99m) Leading institutions in North America & Europe have validated the process Strong intellectual property portfolio 40% of current N.A. supply chain for Tc-99m will be eliminated in 2016 Highly scalable business model leveraging strategic partners 13

  14. WSE: PFM Isotope Market Overview • Tc-99m is the most widely used medical isotope in the world – Allows medical practitioners to image internal body organs – Used in 80%-85% of the 25M diagnostic nuclear medical procedures each year – Common procedures include: • cardiac imaging  gastrointestinal issues • cancer detection bone scans  Imaging of the brain, kidney, spleen and infections • The radioisotope market in Europe alone is expected to reach $1.6B in 2017, up from $1.1B in 2012 – Nearly all of the world's supply comes from the thermal fission of highly enriched uranium (HEU) targets in a small number of highly specialized reactors – Current process is costly and unreliable; raises serious proliferation concerns 14

  15. WSE: PFM Supply Chain Elimination – A Perfect Storm • Beginning in 2016, the National Research Universal (NRU) reactor in Canada will no longer receive government funding for isotope production – 40% of the supply of Tc-99m in North America derived from this one reactor (referred to as the Chalk River Reactor) • The OSIRIS reactor in France is also scheduled to close in 2018 • Without an alternative source of Tc-99m, these planned shut downs will put billions of USD in medical procedures at risk Chalk River, ON 15

  16. WSE: PFM Isotope Production • Completed initial development of new process to produce Tc-99m for medical diagnostic tests  Expected to solve worldwide shortages of Tc-99m  Far less expensive process  Does not require the use of government-subsidized, weapons-grade materials  Designed to improve safety and security of radioactive materials • Process encompasses full production cycle: reactor to final medical supply  Easily deployed worldwide using standard research and commercial reactors  Eliminates the need for special purpose reactors  Stabilizes the worldwide supply of Tc-99m by decentralizing production 16

  17. WSE: PFM Proprietary Production Process Perma-Fix Medical Extract Technetium Insert into Patented Technology Generator Irradiate in standard reactor Purify molly Source natural molly 17

  18. WSE: PFM Isotope Production Current Uranium Process* = N Perma-Fix Molybdenum Process* = *Source: NATIONAL RESEARCH COUNCIL OF THE NATIONAL ACADEMIES 18

  19. WSE: PFM Patents & Licenses • In January 2015, the US Patent Office issued patent to Perma-Fix Environmental Services, Inc. – Allowed all claims in the key patent application – Composition of matter and use patent • Additional patents underway • Third-party license agreements in place 19

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