A NETWORK PERSPECTIVE ON COMORBID DEPRESSION IN ADOLESCENTS WITH - - PowerPoint PPT Presentation

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A NETWORK PERSPECTIVE ON COMORBID DEPRESSION IN ADOLESCENTS WITH - - PowerPoint PPT Presentation

Oct 03, 2023 179 likes •332 views

A NETWORK PERSPECTIVE ON COMORBID DEPRESSION IN ADOLESCENTS WITH OCD Payton J. Jones, Patrick Mair, Bradley C. Riemann, Beth L. Mugno, & Richard J. McNally OCD & Depression Very common for those with OCD (62.7-78.2% life<me;

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Payton J. Jones, Patrick Mair, Bradley C. Riemann, Beth L. Mugno, & Richard J. McNally

A NETWORK PERSPECTIVE ON COMORBID DEPRESSION IN ADOLESCENTS WITH OCD

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  • Very common for those with OCD (62.7-78.2% life<me; Millet et al., 2004)
  • OCD generally comes first (Ricciardi & McNally, 1995)
  • Associated with greater severity (Brown et al., 2015)
  • Elevated suicide risk (Torres et al., 2011)
  • Linked to obsessions, but not compulsions (Ricciardi & McNally, 1995;

Besiroglu et al., 2007)

OCD & Depression

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Common cause model

Cramer, A., Waldorp, L., Van der Maas, H., & Borsboom, D. (2010). Behavioral and Brain Sciences

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Network view

Cramer, A., Waldorp, L., Van der Maas, H., & Borsboom, D. (2010). Behavioral and Brain Sciences

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Nodes Edges Communi<es

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Nodes Edges Communi<es Rela<onships between symptoms Symptoms Disorders

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Centrality

  • Strength
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Centrality

  • Strength
  • Betweenness
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Centrality

  • Strength
  • Betweenness
  • Closeness
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Correla<on Network

r > 0.25

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Graphical LASSO (sparse par<al correla<ons)

γ = 0.3

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Betweenness Closeness Strength

  • agitation

anhedonia compcont compdis compinterf compresis comptime concen decappetite fatigue guilt hypersom incappetite late middle

  • bcontrol
  • bdistress
  • binterfer
  • bresist
  • btime
  • nset

retard sad suicide weightgain weightloss 1 2 3 −2 −1 1 2 −1 1

Graphical LASSO (Sparse par<al correla<ons)

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  • Central symptoms

– Obsessions, sadness, concentra<on problems

  • Communi<es with bridges

– Obsessions, guilt, sadness, concentra<on problems

  • Concentra<on problems are unique
  • Two most common func<onal complaints (Piacen<ni et al., 2003):
  • Problems concentra<ng on schoolwork
  • Doing homework
  • Networks and the future

Conclusions

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Thank you for your aben<on!

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  • Read the preprint: hbps://osf.io/preprints/psyarxiv/8d9kx
  • Adding non-symptom nodes to networks:
  • hbps://osf.io/preprints/psyarxiv/sv58b/
  • hbps://osf.io/preprints/psyarxiv/mh3cf/
  • ResearchGate: www.researchgate.net/profile/Payton_Jones
  • Helpful network tutorials: hbp://psych-networks.com/tutorials/
  • networktools R package:

hbps://cran.r-project.org/web/packages/networktools/ networktools.pdf

Addi<onal Resources