A Comparison of EIT Lung Perfusion Measures Symon Stowe 1 , Alistair - - PowerPoint PPT Presentation

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A Comparison of EIT Lung Perfusion Measures Symon Stowe 1 , Alistair - - PowerPoint PPT Presentation

Jan 02, 2023 140 likes •319 views

A Comparison of EIT Lung Perfusion Measures Symon Stowe 1 , Alistair Boyle 1 , Michal Sage 2 , Mathieu Nadeau 2 , Jean-Paul Praud 2 , @enne For@n-Pellerin 2 , Andy Adler 1 1 Carleton University, OFawa, Canada, 2 Universit de Sherbrooke,

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SLIDE 1

A Comparison of EIT Lung Perfusion Measures

Symon Stowe1, Alistair Boyle1, Michaël Sage2, Mathieu Nadeau2, Jean-Paul Praud2, É@enne For@n-Pellerin2, Andy Adler1

1Carleton University, OFawa, Canada, 2Université de

Sherbrooke, Canada

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 1

symon.stowe@carleton.ca

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SLIDE 2

Why Monitor Lung Perfusion?

  • Pulmonary embolisms are notoriously challenging

to diagnose and monitor

  • Mainly diagnosed using CT pulmonary angiography
  • Associated with radia:on exposure and invasive

administra:on of a contrast agent

  • Clinical need to improve diagnosis and monitoring
  • Safe and low-cost method with few false posi:ves

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 2

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SLIDE 3

Perfusion/Ven,la,on Monitoring

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 3

Perfusion/Ven,la,on match Perfusion/Ven,la,on mismatch

Sample sketches represent ven;la;on and perfusion in a human thorax

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SLIDE 4

Ventilation

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 4

Perfusion

  • Validated and reasonably well

understood

  • Less understood and validated
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SLIDE 5

Perfusion Monitoring Techniques

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 5

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SLIDE 6

Contrast agent measures of perfusion

  • Requires apnoea
  • Non-con0nuous
  • Invasive
  • Can be performed a

limited number of 0mes

  • Provides a series of

blood flow images

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 6

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SLIDE 7

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 7

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SLIDE 8

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 8

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SLIDE 9

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 9

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Experimental Protocol

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 10

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SLIDE 11

Experimental Protocol

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 11

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SLIDE 12

Pulsa&lity Analysis

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 12

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SLIDE 13

Frequency filtering technique

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 13

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SLIDE 14

Shortcomings of Pulsa2lity

  • Heart rate is unstable over

time

  • Many pixels throughout the

image are out of phase

  • Events at the heart rate

frequency are not limited to perfusion

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 14

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SLIDE 15

Conclusion

  • Many challenges accurately es/ma/ng perfusion

from pulsa/lity

  • Preliminary analysis shows correla/on between the

three methods of perfusion measures

  • Comparing both center of mass and overall shape

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 15

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SLIDE 16

A Comparison of EIT Lung Perfusion Measures

Symon Stowe1, Alistair Boyle1, Michaël Sage2, Mathieu Nadeau2, Jean-Paul Praud2, É@enne For@n-Pellerin2, Andy Adler1

1Carleton University, OFawa, Canada, 2Université de

Sherbrooke, Canada

A Comparison of EIT Lung Perfusion Measures, Symon Stowe, 2018/06/11 16

symon.stowe@carleton.ca