[PPT] - 3D PRINTING AS A MEDICAL INNOVATION PLATFORM 3D PRINTING IN THE PowerPoint Presentation

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1 STRATASYS / THE 3D PRINTING SOLUTIONS COMPANY

3D PRINTING AS A MEDICAL INNOVATION PLATFORM

3D PRINTING IN THE MEDICAL DEVICE INDUSTRY

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2 STRATASYS / THE 3D PRINTING SOLUTIONS COMPANY

OUR SPEAKERS TODAY IMAGE OF SCOTT HERE IMAGE OF MICHAEL HERE

SCOTT HANSON

TDS DESIGN LAB MANAGER MEDTRONIC

MICHAEL GAISFORD

DIRECTOR OF MARKETING, MEDICAL SOLUTIONS STRATASYS

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3D PRINTING AT MEDTRONIC: MEDICAL APPLICATIONS AND OUTCOMES

PRESENTED BY: SCOTT HANSON TDS DESIGN LAB MANAGER

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INTRODUCTION

SCOTT HANSON, TDS DESIGN LAB MANAGER TECHNOLOGY AND DEVELOPMENT LAB (A.K.A., “BAT LAB”)

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Technology Development Lab

Product Life Cycle To Ops

Development Technology Post Market Release Special Builds

FULL PRODUCT LIFE CYCLE SUPPORT SYSTEM

Medical Device Value Chain

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We did more theoretical thinking
Played with CAD images
Made prototypes from inconsistent

combinations of materials

Waited:
4-8 weeks for 1st iteration molds
3-6 weeks for 2nd iteration of the mold
3-4 weeks for the final modifications to the

mold

BEFORE 3D PRINTING

Developing without 3D Printing

An improvement of 6 – 10 weeks!

Developing WITH 3D Printing

Weekly

3 4 5 6 7 8 9

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WHY DID MEDTRONIC INVEST IN 3D PRINTING?

Low Barriers to Adoption

Already had the

resources/skills

CAD experience
Stratasys system

ease of use

No special

material handling

Increased Control

Keep intellectual

property in-house

Keep our trade secrets

in-house

Direct control of part

delivery timelines

Develop additive

manufacturing expertise in-house

High ROI

Much lower per

part cost compared to outsourcing

Reasonable

machine cost

Innovation is a core competency in the medtech industry; owning the “innovation engine” is integral.

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What was Medtronic looking for?

High part resolution
System versatility – many applications

from one system (material selection)

High printing speed
Lab friendly, intuitive and reliable

machines

Responsive customer support

What Stratasys machines do we use?

Objet 260TM – initial printer
Objet 500 Connex 3TM - added
Objet 350 Connex 2TM - upgrade Objet

260

Stratasys F370

3D PRINTING - WHAT ARE WE LOOKING FOR?

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Usage

Stratasys printers used every day
Multiple orders received daily
Multiple departments use us
R&D, PD, Manufacturing,

Research, Test Development

Packaging, etc.
Double digit % increases in number
f jobs year-over-year

3D PRINTING EMBRACED

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3D PRINTING OVER TIME

3D Printed Jobs Completed

Rapid Prototyping Concepts & Testing

Human Factor Engineering, Technology Development Anatomical Modeling Development & Test Fixtures

Objet 260 acquired

Objet 500 Connex 3 acquired Upgraded 260 to the Objet 350, Connex 3 Added FDM and acquired F370TM

New 3D Print Applications

Printer Technology

FY14 FY15 FY16 FY17

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3D PRINTING DRIVES SIGNIFICANT SAVINGS

3D PRINTING SAVES VS. MACHINING

Estimated Cost

f Labor Saved

1 Person Submitting Jobs Over 1 Year # of Jobs Needed to Pay for 3D Printer Total Jobs FY16 Jobs 40 250 750 Total Savings $54,000 $340,000 $1,095,000 Days Saved 173 1,080 3,240 (~9 years!)

Increased usage justifies additional printers
Printers paid for themselves in the first year
On average, 3D printed parts delivered 4.5 days faster

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HOW STRATASYS 3D PRINTERS HAVE IMPACTED OUR BUSINESS

MAKE MORE DECISIONS, FASTER!

Speed: parts in

1-2 days

Improved

design: more iterations

Implement: facilitate

new technology customization and integration

Custom: test fixtures

that match exact needs

Clinically relevant:

recreate human pathology

React: respond to

field issues quickly

Decide: more

decisions, faster Technology Development Lab

Product Life Cycle To Ops

Development Technology Post Market Release Special Builds

Medical Device Value Chain

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Challenges

Final design needed quickly and it is never

“perfect” the first time

Need to evaluate multiple design configurations
New design requires assembly changes

Benefits

Can easily print several iterations to optimize
Can print more than one unit
Instruments
Packaging

RAPID PROTOTYPING

ROBUST DESIGN IN SHORTER TIME

Simulated thermal formed packaging tray Tweezer concepts Tiny components of an assembly

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Challenges

Needed new special coiling technology

to enable new device development

Outside vendor solutions cost prohibitive

Benefits

3D print new fixturing to create

in-house implementation

Saved 2 months’ project team cost on

a 1 year long project

Saved $60K in materials and labor
Durable implementation – still using the

3D printed fixturing

CUSTOM TECHNOLOGY DEVELOPMENT

ADAPT NEW TECHNOLOGY TO UNIQUE REQUIREMENTS

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Challenges

Tests need to match the exact

specifications of each product

Need to support multiple testing

scenarios

Functional Testing
Shipping Testing
Electrical Testing

Benefits

FDM Stratasys F370TM is perfect for

building test fixtures

You get the advantages of using the

real plastic (ABS, ASA, PLC, etc.)

Customize to exact product

test requirements

Fast turnaround
Very affordable compared to
utsourced / machine shop
Durable and highly accurate parts

BENCH TESTING

DEVELOP CUSTOM TEST SET-UPS

A. Functional

Testing

C. Electrical

Testing

B. Shipping

Testing

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Challenges

Need bench test equivalence to cadaver models
Animal and cadaver labs are expensive and logistically

difficult to schedule

Benefits

Models match target pathology (based on patient imaging studies)
Quickly replicate most challenging clinical scenarios
Replicates soft and hard tissue in one model (multi-material)
Reduces the number of cadavers required
Reserved for final validation effort unless the model is

validated as for final design testing

Low total cost of testing, shorter development timeline
Educational

PRE-CLINICAL TESTING

CLINICALLY RELEVANT ANATOMICAL MODELS

A. B. C. D. E.

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FIELD ISSUE RESOLUTION

QUICKLY RETURN PRODUCT TO MARKET

Benefits:

Qualified the 2 new molds
Launched new design
Issue was never reported again
Speedy resolution
Product returned to market 2

months earlier than planned

Saved project dollars

Design Issue Tests Prototype Final Product

Challenges:

Resolve problem quickly and get

product back on market

Cables require injected molded

parts with long lead times and expensive processes

Regain customer confidence with

a more robust design

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The Bat Lab

Objet printers are in a dedicated room
Objet cleaners are in a separate room
FDM printer is versatile enough to be

placed anywhere in the lab

3D PRINTING FLOOR LAYOUT AND DISPLAY

3D Printing Display

Created for touring internal

and external customers

Educates employees

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IN SUMMARY

Integrate 3D printing into how we bring products to market
Reduce project costs and accelerate time to market
Develop more robust designs

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20 STRATASYS / THE 3D PRINTING SOLUTIONS COMPANY

UNLOCK INNOVATION AND ACCELERATE PROCESSES WITH 3D PRINTING

MICHAEL GAISFORD DIRECTOR OF MARKETING, STRATASYS HEALTHCARE 3D PRINTING IN THE MEDICAL DEVICE INDUSTRY

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For more than 25 years, Stratasys has been at the forefront of 3D printing and additive manufacturing innovation.

STRATASYS OVERVIEW

21 STRATASYS / THE 3D PRINTING SOLUTIONS COMPANY

HEADQUARTERS EDEN PRAIRIE, MN AND REHOVOT, ISRAEL OVER 1,200 GRANTED OR PENDING ADDITIVE MANUFACTURING PATENTS GLOBALLY $673 MILLION REVENUE (2016) OVER 30 TECHNOLOGY AND LEADERSHIP AWARDS PUBLICLY TRADED ON NASDAQ (SSYS)

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22 STRATASYS / THE 3D PRINTING SOLUTIONS COMPANY

Full color 3D printing on Stratasys J750 3D Printer

POLYJET SYSTEMS

Multi-texture to combine soft and hard tissue Quick turn around injection molds usable with end use materials High resolution printing to replicate fine details

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23 STRATASYS / THE 3D PRINTING SOLUTIONS COMPANY

Range of high grade thermoplastics
Durable parts for production part manufacturing
Functionally test prototypes
Biocompatible and sterilizable options

FUSED DEPOSITION MODELING (FDM)

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24 STRATASYS / THE 3D PRINTING SOLUTIONS COMPANY

3D printing can reduce costs, improve patient care or increase speed at every step in the medical device value chain. Stratasys solutions enhance economics and outcomes of medical solutions

RAPID PROTOTYPING REALISTIC ANATOMICAL MODELS PRODUCTION PARTS, JIGS AND FIXTURES PHYSICIAN TRAINING AND SALES AIDS PATIENT- SPECIFIC SOLUTIONS FULL RANGE OF ADDIVITIVE MANUFACTURING USE CASES RESEARCH & DEVELOPMENT PRECLINICAL TESTING MANUFACTURING MARKETING & PHYSICIAN EDUCATION CLINICAL LIFECYCLE MANAGEMENT