2018 Pricing Reform: Will Takeda Exit the Japanese Pharma Market? - - PowerPoint PPT Presentation

2018 pricing reform will takeda exit the japanese pharma
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2018 Pricing Reform: Will Takeda Exit the Japanese Pharma Market? - - PowerPoint PPT Presentation

2018 Pricing Reform: Will Takeda Exit the Japanese Pharma Market? Japan Pharma & Governance Tour: UBS Securities e-Projection K.K. July 12, 2018 e-Projection Three Forces Determining the Direction of Healthcare Shape of the market will


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SLIDE 1

e-Projection

2018 Pricing Reform: Will Takeda Exit the Japanese Pharma Market?

Japan Pharma & Governance Tour: UBS Securities e-Projection K.K. July 12, 2018

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SLIDE 2

e-Projection

Three Forces Determining the Direction of Healthcare

Shape of the market will depend on the priorities and the balance of the forces

Industry

Driver

R&D

Vehicle

RoI

Key Incentive

Patients&HCP

Driver

Advocacy

Vehicle

Well being

Key Incentive

Authorities

Driver

P&MA

Vehicle

Fiscal discipline

Key Incentive

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SLIDE 3

e-Projection

Broken NHI System Casting a Shadow on Healthcare

Structural and operational malfunction leading to de-prioritization of innovation

Leaky: unhealthy healthcare

Insurance premium 49% Injection of public funds 39% Patient copay 11% Others 1% Source of National Healthcare Funds (2015)

Source: MLHW statistics

The Japanese pricing authorities’ inabilit lity a and unwi willin llingness t to value n new d drugs is harming innovation Pricetags: way off the target

Opdivo initial prices in different markets

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SLIDE 4

e-Projection

’18 Reform: Changing the Environment Dramatically

Incentives were repealed without any compensative measures

  • Revision of the Price Maintenance

Premium

  • Frequency of price cuts increase

from biennial to annual

  • Flexible re-pricing in response to

“Market Expansion” allowing massive price cuts to happen anytime

  • Measures to estimate the intrinsic

value of the products, e.g. HTA, failed to be implemented effectively Initiatives Implications Deceleration in market growth of new drugs Decreasing the consistency of the business Possibility of erroneous initial prices granted

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SLIDE 5

e-Projection

Loss of exclusivity

Ramifications of the ’18 Pricing Reform

Business prospects will deteriorate with low predictability early in the lifecycle

20 40 60 80 100 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

Years post launch

Price dynamics over the life cycle of new drugs

20 40 60 80 100 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

Years post launch

Price dynamics over the life cycle of new drugs

20 40 60 80 100 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

Years post launch

Price dynamics over the life cycle of new drugs

Prices of new drugs used to be maintained during the lifecycle until LOE Prices will be reduced significantly at LoE and then will be cut thereafter in line with competition After ‘18, prices will be cut regardless of exclusivity “Re-pricing” may happen at any arbitrary timing and extent Initial Price

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SLIDE 6

e-Projection

Takeda: Time to say da svidania to Japan?

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e-Projection

Consultant and pharmaceutical forecasting expert with global and local experience spanning across areas of commercial and R&D. Prior to being the president of e-Projection, he was a Director of Sales Forecasting and Analytics at Takeda Pharmaceuticals. Before Takeda, he worked at Abbvie, engaged in various positions in Global Marketing and the Japan affiliate. Relevant education includes Ph.D. in medicine from Shinshu University and MBA from University of Chicago Booth School of Business with honors. Website: http://e-projection.com/ E-mail: tosh.nagate@e-projection.com

Tosh Nagate Ph.D. MBA. CEO & Chief Analyst at e-Projection

From conjecture to confidence.