1 Introduction of XtremIA 5th of December 2017 10 Janvier 2016 - - PowerPoint PPT Presentation

1
SMART_READER_LITE
LIVE PREVIEW

1 Introduction of XtremIA 5th of December 2017 10 Janvier 2016 - - PowerPoint PPT Presentation

1 Introduction of XtremIA 5th of December 2017 10 Janvier 2016 Pierrick DREVILLON, Msc, MBA ESCP (Paris) Co-foundeur of Xtremia INSEMINATION 2.0 FOR ALL FARMERS , FOR ALL SPECIES A T TECHN HNICAL CAL REVOLU LUTI TION, ON,


slide-1
SLIDE 1

1 10 Janvier 2016

Introduction of XtremIA – 5th of December 2017

slide-2
SLIDE 2

INSEMINATION 2.0 … FOR ALL FARMERS , FOR ALL SPECIES

Pierrick DREVILLON, Msc, MBA ESCP (Paris) Co-foundeur of Xtremia

slide-3
SLIDE 3

THE DEEP ARTIFICIAL INSEMINATION: AN ALREADY MASTERED TECHNIQUE!

A T TECHN HNICAL CAL REVOLU LUTI TION, ON, INSEMIN MINATION ATION 2.0.

slide-4
SLIDE 4

4

110 million

  • f AI in the

world 1 / 2 cow in France 80% of born piglets ≈ 100 000 mares inseminated / year 2.8% of born children in France Almost 100% for some bird species like turkey AI : a growing ng-up p techniq nique ue for the last t 70 70 years !

AI : an omnipresent technique in the world …

slide-5
SLIDE 5

Selection at the expense

  • f fertility

↑ of the number of animals with genital risks

Use of new biotechnologies

Insufficient heat detection

On average:

  • 50% fertility on Montbéliarde

cows in AI1

  • 45% in Normande cows
  • ≈ 35% in Holstein cows

(Le Mezec et al, 2010)

  • Negative genetic

correlations between milk production and fertility

  • Selection of overturned

basin animal  uro/pneumovagina

  • Sexed semen (2M

spz/dose) ≠ conventional semen (10M spz/dose)

  • Lack of expression (low

P4 rates)

  • Lack of observation by

the breeder

5

An increasingly reduced fertility in World Dairy farms…

slide-6
SLIDE 6
  • AI in fresh
  • Dose price: 3-7€
  • Goal: prolificacy
  • AI in fresh and frozen
  • Dose price: 200-3 000 €
  • Goal: low [dose]
  • AI in fresh and frozen
  • Dose price: 25-50 €
  • Goal: Sexed semen

6

Development of Deep AI in species Genital tracts

slide-7
SLIDE 7

75 cm

Ghent Device (University of Gand), Aspi Gun (IMV), Extra-Flex (Minitüb) Equine deep AI catheter (Minitüb) DeepGoldenPig (IMV), Gédis (Gènes Diffusion), UnicSoft (Cobiporc)

?

7

Development of Deep AI in species Existing DAI devices

slide-8
SLIDE 8

A TECHNICAL TECHNICAL RE REVOLUTIO VOLUTION, N, IN INSEMINATIO SEMINATION N 2. 2.0. 0.

slide-9
SLIDE 9

9

XtremiA : a real changing equipment …

The final touch...

  • Drop the semen up to 25 cm into

the uterine horn.

  • Without any constraint for the
  • perator: the material adapts

itself to the animal anatomy.

  • Perspective of diversification in

ET. A safe handling…

  • Direct use of 0.25ml straws in the device : no risk
  • f destruction of the sperm.
  • Drop off by a retraction of the sheath : securing the

gesture for the animal. Health safeguards…

  • Individual packages with sanitary

sheats.

  • Consumable and non reusable

sheats.

slide-10
SLIDE 10

10

Xtrem-ET : the revolution in embryo transfer

Reduced cross-section for a better passage through the closed cervixes of recipients of heifers Rounded extremity with a dilatory effect to facilitate the catheter’s progression into the cervixes

Esayslide, a specific cap with a lateral exit … Time for Embryo Transfer 2.0

slide-11
SLIDE 11

11

Xtrem-ET : the revolution in embryo transfer

The first transfer device for all users ! Improved results The end of spinal anaesthetic Use cows as recipients !

slide-12
SLIDE 12

NON-EXHAUSTIVE APPLICATION EXAMPLES IN BREEDING

A T A TEC ECHN HNICAL CAL REV EVOLUTI LUTION, ON, INSEMIN MINATION ATION 2.0.

slide-13
SLIDE 13
  • 1. SEXED SEMEN
slide-14
SLIDE 14

5 h 7h 9h 11 13 15 17 19 21 23 1 3 5 7 9 11 13 14

Number of spermatozoids/AI dose

2 12 10 8 6 4

Spectrum of action of the male spermatozoids Spectrum of action of the female spermatozoids Spectrum of action of the female sexed semen

Heat detection

In millions of spermatozoids/AI dose Time

IA

Minimum 12h Fertilization window Sexed semen

slide-15
SLIDE 15

Billion Millions Thousands

slide-16
SLIDE 16

Spermatozoids in strength and number

Millions

slide-17
SLIDE 17

17

Results of the tests conducted during summer 2014

Experimental results:

  • Calving rates, depending on the type of semen

48.7% 51.3% 42.3% 57.7% Sexée Gestation Sexée Pas de gestation 0.00% 10.00% 20.00% 30.00% 40.00% 50.00% 60.00% 70.00% E T

+ 15.2% difference(+ 6.43 pts) !

a b b a N = 314 N = 662

slide-18
SLIDE 18
  • 2. EMBRYOS
slide-19
SLIDE 19

19

The epidural: a working comfort, a guarantee for the breeder, but…

slide-20
SLIDE 20

Simplified pose No more epidural

slide-21
SLIDE 21
  • 3. HIGHLY PRODUCING COWS
slide-22
SLIDE 22

Ketones ↑ the prevalence of mucus ↑ the appearance of free radicals ↑ the inflammation

slide-23
SLIDE 23
  • 4. THE CASE OF THERMAL STRESS
slide-24
SLIDE 24

THERMAL STRESS

slide-25
SLIDE 25

THERMAL STRESS

slide-26
SLIDE 26

ALL OF US HAVE TO IMAGINE THE TOMORROW’S APPLICATIONS...

www.xtremia.fr Suivez-nous sur Facebook ! XtremiA remiA

slide-27
SLIDE 27

www.xtremia.fr