Welcome H.O.P.E. Designer Drugs Information Session H.O.P.E. - - PowerPoint PPT Presentation

Welcome

H.O.P.E. Designer Drugs Information Session

H.O.P.E. Educational Material. hopehandsdon@gmail.com / 353-(0)1-887-8404

Agenda What is the current issue? Signs, symptoms User Testimony Health issues Working with a User Recovery Solutions

Synth thetic etic drugs s are e consi sist sten ently tly changi nging.

• ng. Law

en enforceme cement nt, doctor tors, s, addictio ction n profes essio siona nal l have e tr trouble ble kee eeping g up. PVP, MP MPVD VD, Me Meth thampheta etamin ine e follow low a l long line ne

• f synth

thet etic ic drugs th that t have e poppe ped d up in rec ecen ent t yea ears such as spice ce and bath th salts ts th that t conta tain in ingred edie ient nts s such h as me meth thadrone

• ne and met

ethylon

• ne

e (simi mila lar MD MDMA MA) and bei eing g sold as Spice ice, bath thsal salts ts, incen ense se. . When en th the h e hea ead shops s wer ere e clos

• sed

ed in August st 2010, sales es wen ent t under ergrou ground nd and on th the e inte ternet. et.

H.O.P.E. Educational Material. hopehandsdon@gmail.com / 353-(0)1-887-8404

Press Coverage

First report of seizure: The Irish Examiner September 19, 2012 23kg of synthetic drugs were caught coming from China into Waterford City. PVP, methylone, and flephedrone — which mimic the effects of street drugs, ecstasy, cocaine and amphetamine. Many arrests from 2012, in possession of these designer drugs August / September 2014: being reported that North Inner City dealers have been selling drugs that they claim is crystal meth for €20 a bag. Bag was analysed and found to contain MDPV and PVP. September 30: Arrests in Mary’s mansion after six week operation.

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What is Amphetamine?

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A synthetic drug that stimulates the heart and respiration, constricts blood vessels and induces sleeplessness. First synthesized in Germany 1887. Originally marketed as Benzedrine in the 1920s and was used for suppressing appetite or preventing narcolepsy. Were available over the counter and quickly became a favorite street drug known as "pep pills" or "Bennies." Used by U.S. air force during WW II to keep pilots awake on long

• missions. Also used by German and Japanese soldiers. End of World

War II 2% of Japanese adults were dependent on amphetamines. Late 50’s people were injecting content of Benzedrine inhalers. Performance-enhancing drug by athletes. Now available by low-dose prescription generally used to treat ADD, narcolepsy and to control weight.

 A chemical variation  It is a white or off-white, odorless, bitter-tasting crystalline powder that easily dissolves in water  Has a much stronger stimulant effect on the central nervous system  It is more addictive than the original drug. Severely restricted beginning in the 1950s.  Periods of Meth Epidemic 50’s, late 60’s and a 3rd epidemic started in mid 90’s  Now available by low-dose prescription form as Dexedrine or Desoxynl and is generally used to treat ADD, narcolepsy and to control weight.

Crystal Methamphetamine

Home Made from Highly Toxic Substances

• Antifreeze
• Medicine containing ephedrine or pseudoephedrine
• Match-box striker (Red phosphorous)
• Hydrochloric acid
• Lantern fuel
• Starter Fluid (Ether)
• Denatured Alcohol
• Anhydrous Ammonia (fertilizer)
• Paint Thinner (Acetone??)
• Sulfuric Acid (Battery Acid and Drain Cleaner)
• Hydrogen Chloride Gas
• toluene(brake fluid)
• iodine(vet. products)
• sodium hydroxide (lye),
• rock salt
• kitty litter

What is Alpa PVP?

 Sold in Dublin as Crystal Meth. Known in USA as Gravel  a-PVP, α-Pyrrolidinopentiophenone is an alkaloid in the pyrrolidine and

ketone chemical classes, functioning as a norepinephrine-dopamine reuptake inhibitor (NDRI) and acting as a stimulant on the central nervous system and cardiovascular system.

 a-PVP was developed in the 1960 and has been available on

the research chemical market for several years now, and is used as a recreational drug.



A-PVP often comes in either a white, tan, or a yellowish powder, it is also available in very small white crystals or powder

MDPV

• Methylenedioxypyrovalerone (MDPV) is a psychoactive

drug with stimulant properties which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI). four times the potency of Ritalin.

• Formerly sold in head shops as a legal high as bath

salts.

• First developed in the 1960s by a team at Boehringer

Ingelheim there is no approved medical use.

H.O.P.E. Educational Material. hopehandsdon@gmail.com / 353-(0)1-887-8404

• Injected
• Snorted
• Smoked
• Orally

Crystal Meth MPVD PVP

Euphoria Euphoria Euphoria Very high energy Very high energy Very high energy Lose inhibitions Lose inhibitions Lose inhibitions Increased Libido Increased Libido Grinding Teeth Grinding Teeth Muscle Tension Hallucinations Hallucinations Hallucinations Compulsive use – MORE Compulsive use – MORE Compulsive use – MORE Cant eat or sleep Cant eat or sleep Cant eat or sleep Paranoia / psychoses Paranoia / psychoses Paranoia / psychoses Suicidal thoughts Suicidal thoughts Suicidal thoughts Come down: Depression, exhaustion, obsession Come down: Depression, exhaustion, obsession Come down: Depression, exhaustion, obsession Skin Bugs

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H.O.P.E. Educational Material. hopehandsdon@gmail.com / 353-(0)1-887-8404

Crank Bugs:

The body's natural reaction is to try and eliminate the

• toxins. Users itch and

scratch which causes the

• pen sores.

“Meth Mouth”

All that comes with the Erratic Addictive behaviours - Financial / Legal / Order / Intimidation problems A rise in domestic disputes Children:

• risk of being exposed to toxic fumes, fire, and chemical burns
• Exposure to drugs and unsanitary conditions
• Increase in child abuse and neglect cases
• Increased risk for substance abuse among children in later life
• attachment disorder / parents fail to respond to basic needs.
• Caregivers become careless, irritable, and violent

Pregnancy: Possible effects found in the few human studies that exist include increased rates of premature delivery, placental abruption (early separation of a normal placenta from the wall

• f the uterus), retarded fetal growth, and cardiac and brain

abnormalities.

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Recovery and Treatment

H.O.P.E. Educational Material. hopehandsdon@gmail.com / 353-(0)1-887-8404

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Overdose treatment for Crystal Meth

• Often treated with benzodiazepines, to lessen the drug-induced activity in

the brain and body.

• In some cases, general anaesthesia was used because sedatives were

ineffective.

• Treatment in the emergency department for severe hypertension,

tachycardia, agitation, or seizures consists of large doses of lorazepam in 2– 4 mg increments every 10–15 minutes intravenously or intramuscularly. It has been found that the use of any beta blockers to treat hypertension in these patients can cause a dangerous rise in blood pressure.

• Alternatively, Clonidine has been used clinically in the treatment of acute

stimulant intoxication and withdrawal

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Withdrawal symptoms of all amphetamine type drugs

User becomes depressed Becomes lethargic, has no energy Craving for more May feel suicidal

Harm Reduction: There is no way to reduce the direct harm of these type of drugs – the very nature of the effects, you cannot ask people to control their use or use less. They need help and support to stop. The harm reduction around associated behaviors are the same as with any

• ther drug – safe / clean injecting, and condom use.

There are no pharmacological treatments or substitutions for designer drug / methamphetamine dependence. Antidepressant medications can be used to combat the depressive symptoms

• f withdrawal.

H.O.P.E. Educational Material. hopehandsdon@gmail.com / 353-(0)1-887-8404

The most effective treatment for addiction is cognitive behavioral interventions, which modify a patient's thinking, expectancies, and behavior while increasing coping skills to deal with life stressors. Residential Treatment can be affective in getting someone some distance from the use, and an

• pportunity to learn relapse prevention skills.

Recovery support groups are also effective and can lead to long-term drug-free recovery.

Q & A

• www.justice.gov/methawareness/
• www.methresources.gov
• www.methwatch.com
• www.drugfree.org
• www.crystalmeth.org
• www.acsh.org



Substance Abuse and Mental Health Services Administration. (SAMHSA)



Office of National Drug Control Policy. (ONDCP)



National Institute on Drug Abuse. (NIDA)

H.O.P.E. Educational Material. hopehandsdon@gmail.com / 353-(0)1-887-8404