welcome and introduction
play

Welcome and Introduction Andy Evans, Chair, MMIP Welcome and - PowerPoint PPT Presentation

Mar 27, 2023 •405 likes •952 views

Welcome and Introduction Andy Evans, Chair, MMIP Welcome and Introduction Professor Sir John Bell, Life Sciences Council Kristen McLeod Director, Office for Life Sciences Dr Richard Torbett Chief Executive, ABPI Housekeeping Your

  2. Welcome and Introduction Andy Evans, Chair, MMIP

  3. Welcome and Introduction Professor Sir John Bell, Life Sciences Council

  4. Kristen McLeod Director, Office for Life Sciences

  5. Dr Richard Torbett Chief Executive, ABPI

  6. Housekeeping Your Participation • Please continue to submit your text questions and comments using the Questions panel we will try and get to as many as possible where time allows. Note: Today’s presentation is being recorded and slides will be made available after the webinar Medicines Manufacturing Industry Partnership (MMIP)

  7. Trinity of academia, industry and government – driving manufacture of COVID-19 vaccines

  8. Kate Bingham Chair, UK Vaccine Taskforce Managing Partner SV Health Investors

  9. Andy Jones , Challenge Director: Medicines Manufacturing ISCF Lucy Foley , Director of Biologics, CPI Dr Catherine M. Green , Associate Professor, Head of the Clinical BioManufacturing Facility, University of Oxford Prof. Daniel C Smith , Chief Scientific Officer, Cobra Biologics Mark Proctor , Global Supply & Strategy Snr. Director, AstraZeneca Ian McCubbin OBE , Independent Pharmaceutical Professional

  10. BIA COVID-19 Vaccine Taskforce members www.bioindustry.org

  11. BIA COVID-19 Vaccine Taskforce members www.bioindustry.org

  12. Housekeeping Your Participation • Please continue to submit your text questions and comments using the Questions panel we will try and get to as many as possible where time allows. Note: Today’s presentation is being recorded and slides will be made available after the webinar Medicines Manufacturing Industry Partnership (MMIP)

  13. Questions? Medicines Manufacturing Industry Partnership (MMIP)

  14. Break Back at 12:20 Medicines Manufacturing Industry Partnership (MMIP)

  15. Housekeeping Your Participation • Please continue to submit your text questions and comments using the Questions panel we will try and get to as many as possible where time allows. Note: Today’s presentation is being recorded and slides will be made available after the webinar Medicines Manufacturing Industry Partnership (MMIP)

  16. MMIP Workstream Updates

  17. Technology & Innovation Martin Wallace, GSK

  18. Technology & Innovation Workstream Name Affiliation Theme Katie Murray AZ/MMIC/HVMC Small Molecule Lucey Foley CPI Biologics Large Molecule Julie Anderson CPI Strategy General/Secretariat Martin Wallace GSK General/Lead JP Sherlock AZ Small Molecule Bob Docherty Pfizer Digital & Analytics James Miskin OxfordBiomedica ATMP Sarah Goulding KTN Large Molecule/AT Stephen Ward ATMP/HVMC ATMP Damian Marshall Kit Erlebach Fujifilm D iosynth BIA/MAC Large Molecule Melissa Hanna Brown Pfizer, Analytics (CAMS) Small Molecule Karen Wilkinson KTN/Made Smarter Digital Nick Medcalf Anna Mereu Innovate UK/Medicine Challenge General Patrick Hyett GSK Digital Medicines Manufacturing Industry Partnership (MMIP) Slide 18

  19. Critical Questions to consider for technology Roadmapping • What are the drivers we need to consider in the future? • Where do we want to be in 2030? ► • What are the opportunities that will be afforded based on advances in science and technology? • What are the current barriers to adopting this technology? Medicines Manufacturing Industry Partnership (MMIP)

  20. MMIP T+I Roadmap: Grand Challenges for 2021 and beyond Infrastructure Strategic Grand Challenges Technology opportunities Drivers Current • Providing access to innovative Digital Design – from Molecule to • Digitalisation Expanded medicines Cell+Gene patient therapy • Continuous Manufacturing manufacturing • Moving towards personalised centre • ATMPs manufacturing & delivery medicines. On Demand Manufacturing National Medicines Biologics Manufacturing • Delivering a Net Zero economy Manufacturing Innovation On Demand Sterile manufacturing Centre centre Potential Future • capacity Changing Portfolio - Advanced Public Funded • Robust Agile Supple Chains Therapies – ADCs, Vaccines, manufacturing Nucleic Acids, Oligos, Cell based infrastructure Real time release for Advanced • Micro Flexible Factory therapies Therapies Vaccines • A Net zero approach to Nucleic Acid Manufacturing • Shortening Development and Therapies Innovation Accelerator medicines manufacture centre Launch times • Modular, flexible Sterile • Harnessing the potential from the National Formulation Manufacture UK medicine manufacturing Centre ecosystem • Advanced Bioprocess Manufacturing & Control • Increase the impact of Digital Transformation from molecule to • Intracellular drug delivery patient

  21. Initial MMIP T+I Roadmap: Programmes and potential Projects that underpin the GCs Deliver a more agile, adaptable, scalable, sustainable medicine manufacturing ecosystem that will deliver medicines to patients faster in a more sustainable way. Next Generation Modular Flex Sterile Robust Agile Supply Net Zero Medicine Micro Flex Factory Intracellular Delivery Biopharma Manufacturing Supply chains manufacture Delivering alternative Advanced bioprocess Factory on Demand Molecule to Patient Lipidic & Polymeric Cleanrooms to meet green manufacturing Control Nanoparticles future needs processes for existing Cell free systems therapies Expanding the impact of Industrialising Viral Vector Targeted Delivery Digitisation of sterile process intensification Manufacture Delivering Net Zero operations manufacturing processes Development of a smart for new therapies bioreactor • Modular and • Characterisation of • API to DP Connectivity • Cleanrooms for complex • Alternative Oligo • Drug Product Digital twins Mobile factory processes in flow therapies e.g ADCs Manufacturing • In process control and • Small batch process • Rapid Micro solutions • Delivering more • Digitally enabled • Miniaturisation of FF intensification real time release. sustainable • Downstream processes small operations. manufacturing volume/batch Digital twins – e.g. Lyo processes • Shortening development factory • Net Zero supply chain of • Plug & Play and production times the future. Automation for stratified medicines Solutions and biologics to combat emerging threats (aka cell free).

  22. Roadmap refresh • We are in the process of updating the technology roadmap – Last roadmap issued in 2017 (A lot has changed since then!) • We will use this revised roadmap to help align all relevant stakeholders to deliver more agile, adaptable, scalable, sustainable medicine manufacturing ecosystem that will deliver medicines to patients faster in a more sustainable way. Medicines Manufacturing Industry Partnership (MMIP)

  23. Advanced Therapies Workstream - update James Miskin MMIP Advanced Therapies Work Stream Lead July 2020 Medicines Manufacturing Industry Partnership (MMIP) Slide 23

  24. Advanced therapies – a new treatment paradigm Established mode Clinical proof of Manufacturing, of action concept COGs Clear unambiguous Rare diseases; Requirement for e . g. β -Thalassaemia, clinical data in severe mid- to large-scale, ✓✓ disease, ‘accelerated’ ADA-SCID, high quality vector / haemophilia, orphan route to market cell manufacturing ocular ? with ‘ acceptable ’ COGs (for developers and payers) Promising signs of High incidence / efficacy in clinical prevalence ✓ Scaled clinical trials, ‘traditional’ diseases; operations e.g. Parkinson’s route to market? disease, CF, cancer Indication-specific (e.g. CAR-T, TCR) ATMP CMC is extremely complex therefore manufacture is ‘sticky’ Slide 24 Medicines Manufacturing Industry Partnership (MMIP) Slide 24

  25. MMIP Advanced Therapies Work Stream Priority areas for MMIP AT work stream, collectively aimed at securing a significant UK position in ATMPs : • Skills – apprenticeships, AToMIC, LEAP, CATTS • Future support for capability and capacity for ATMPs manufacture – “Accelerating the Translation of the UK Academic ATMP Pipeline into Commercial Products that will be made in the UK” • Plus : improving the UK fiscal environment for medicines manufacturing (including ATMPs) Slide 25 Medicines Manufacturing Industry Partnership (MMIP) Slide 25

  26. The ATAC story Life Sciences Industrial Science Man Tech (L3), Senior Leader (L7) Strategy Reg Affairs (L7) £1.5m Continued Gatsby & MA Scotland launched MMIP ATM funding – and CGT interim Taskforce ATAC funding Research Scientist Future Skills launched (L7), Process Eng (L6) 2030 launch and Lab Tech Wales to be launched 2019 2016 2017 2018 2020 2014 2015 First AT Apprenticeship CGTC Skills Catapult Present skills – 17 ATMP Gatsby Delivery of and Training Skills strategy to BEIS Technician Scientists Foundation Action Plan - Survey (L5) from 8 orgs demand interim skills to MAC Action survey funding Plan Medicines Manufacturing Industry Partnership (MMIP) Slide 26

Download Presentation
Download Policy: The content available on the website is offered to you 'AS IS' for your personal information and use only. It cannot be commercialized, licensed, or distributed on other websites without prior consent from the author. To download a presentation, simply click this link. If you encounter any difficulties during the download process, it's possible that the publisher has removed the file from their server.

Recommend

INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION

INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION

TRAINING COURSE ON SOCIAL PROTECTION & FORMALIZATION TRINIDAD AND TOBAGO MARCH 15, 2017 INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION INTRODUCTION Design of the NIS Assistance from the

547 views • 23 slides
INTRODUCTION Introduction 2/42 INTRODUCTION Alternations I am giving bread to the

INTRODUCTION Introduction 2/42 INTRODUCTION Alternations I am giving bread to the

Patterns of variation in the expression of case and agreement Andrs Brny Leiden University Centre for Linguistics 9 November 2019, BaSIS Workshop a.barany@hum.leidenuniv.nl INTRODUCTION Introduction 2/42 INTRODUCTION

1.37k views • 42 slides
Introduction Introduction Introduction Introduction Outline Motivation Failures

Introduction Introduction Introduction Introduction Outline Motivation Failures

Introduction Introduction Introduction Introduction Outline Motivation Failures Definition and concepts Process and product properties Principles SE Approaches Motivation Software and the economy The economies of

1.03k views • 49 slides
Introduction Introduction Introduction Nationwide Cause for Concern 1

Introduction Introduction Introduction Nationwide Cause for Concern 1

Introduction Introduction Introduction Nationwide Cause for Concern 1 https://www.cdc.gov/std/stats17/infographic.htm Introduction Epidemiology in Western Colorado CPHE Surveillance Data Report, May 2018 Chlamydia Epidemiology in Western

977 views • 39 slides
DAQ introduction Purpose of this talk : (1) Introduction for those who have not been in every

DAQ introduction Purpose of this talk : (1) Introduction for those who have not been in every

DAQ introduction Purpose of this talk : (1) Introduction for those who have not been in every meeting (2) Some ideas of diagrams for section 7.1 (Introduction) of TP. Giles Barr 25 Jan 2018, Pembroke College On DUNE, the reality is there is a

474 views • 10 slides
INTRODUCTION cf. Schneider, Chapter 1 INTRODUCTION THEY ARE OUT TO GET YOU INTRODUCTION WHAT

INTRODUCTION cf. Schneider, Chapter 1 INTRODUCTION THEY ARE OUT TO GET YOU INTRODUCTION WHAT

ADVANCED COMPUTER SECURITY INTRODUCTION cf. Schneider, Chapter 1 INTRODUCTION THEY ARE OUT TO GET YOU INTRODUCTION WHAT IS SECURITY? A systems security policies describe What the system is supposed to do Store and provide access

479 views • 16 slides
Overview Introduction to SMIL Introduction to W3C and XML Introduction to SMIL

Overview Introduction to SMIL Introduction to W3C and XML Introduction to SMIL

Overview Introduction to SMIL Introduction to W3C and XML Introduction to SMIL Writing a SMIL file Adding Media Objects Martin Halvey Clipping media files January 2008 Timing and Synchronising Layout World Wide

387 views • 14 slides
14 Introduction Introduction Bad guys can put malware into Example: hosts

14 Introduction Introduction Bad guys can put malware into Example: hosts

Introduction Introduction source Encapsulation ISO/OSI reference model message M application segment H t H t M transport network datagram H n H n H t M presentation: allow applications to frame link H l H n H t M interpret

583 views • 4 slides
Previous Lecture Introduction to SMIL 2 Introduction to W3C and XML Introduction to SMIL

Previous Lecture Introduction to SMIL 2 Introduction to W3C and XML Introduction to SMIL

Previous Lecture Introduction to SMIL 2 Introduction to W3C and XML Introduction to SMIL Writing a SMIL file Adding Media Objects Martin Halvey Clipping media files January 2008 Timing and Synchronising Layout

322 views • 8 slides
Lecture 1 Andreas Habegger Introduction Zynq Introduction Zynq Introduction Zynq PS vs. PL

Lecture 1 Andreas Habegger Introduction Zynq Introduction Zynq Introduction Zynq PS vs. PL

Introduction Zynq Lecture 1 Andreas Habegger Introduction Zynq Introduction Zynq Introduction Zynq PS vs. PL Processing System Processor Peripherals Data Buses AXI Bus Conclusion BTE5380 - Embedded Systems Octobre 2014 Andreas Habegger

1.81k views • 30 slides
2018.06 01 SMILE5 Introduction S E 5 02 Alpha Cloud M I L 03 Company Introduction 04

2018.06 01 SMILE5 Introduction S E 5 02 Alpha Cloud M I L 03 Company Introduction 04

2018.06 01 SMILE5 Introduction S E 5 02 Alpha Cloud M I L 03 Company Introduction 04 Project References S E 5 PART.1 SMILE5 Introduction M I L Introduction STORION-SMILE5 Residential Energy Storage System Inverter 5kW Output Input

1.06k views • 25 slides
Introduction to CICS Course introduction Course introduction What is CICS? What is an

Introduction to CICS Course introduction Course introduction What is CICS? What is an

Introduction to CICS Course introduction Course introduction What is CICS? What is an application server? Why use an application server? Course introduction Services provided by CICS How CICS applications are defined Scaling CICS to meet

1.84k views • 146 slides
Network Visualization Introduction Presented by Shahed Introduction Introduction Basic

Network Visualization Introduction Presented by Shahed Introduction Introduction Basic

Network Visualization Introduction Presented by Shahed Introduction Introduction Basic building blocks Node Links (relationship between nodes) Spatial information Network data

584 views • 9 slides
Introduction Introduction (1) Main argument of the paper: universities are not only

Introduction Introduction (1) Main argument of the paper: universities are not only

Le jugement des pairs comme outil de management des universits Peer-review as a management tool Christine Musselin (CSO, Sciences Po et CNRS) Avril 2013, Lirrsistible ascension du capitalisme acadmique Introduction Introduction (1)

590 views • 28 slides
Introduction Introduction to storage and to storage and filesystems filesystems Introduction

Introduction Introduction to storage and to storage and filesystems filesystems Introduction

Moreno Baricevic Gilberto Daz Axel Kohlmeyer Stefano Cozzini ULA ICTP CNR-IOM DEMOCRITOS Merida, VENEZUELA Trieste, ITALY Trieste, ITALY Introduction Introduction to storage and to storage and filesystems filesystems Introduction

1.19k views • 51 slides
JABLOTRON JA-100 introduction November 2011 Introduction Todays goals First introduction of

JABLOTRON JA-100 introduction November 2011 Introduction Todays goals First introduction of

JABLOTRON JA-100 introduction November 2011 Introduction Todays goals First introduction of the brand new JA-100 alarm system Visions Basic architecture System components Setting Help us with final validations You are the FIRST ones

1.69k views • 111 slides
Semantic Web Adoption Ivan Herman, W3C First China Semantic Web Symposium (CSWS 2007), Beijing,

Semantic Web Adoption Ivan Herman, W3C First China Semantic Web Symposium (CSWS 2007), Beijing,

Semantic Web Adoption Ivan Herman, W3C First China Semantic Web Symposium (CSWS 2007), Beijing, China, 2007-11-19 (2) > Semantic Web adoption SW technologies go back to few years now we have a really stable set of specifications since

737 views • 47 slides
ministration Care Admi Healt Health IT In IT Init itia iativ ives es Pamela King HIE

ministration Care Admi Healt Health IT In IT Init itia iativ ives es Pamela King HIE

Ag Agen ency cy f for or Hea Health ministration Care Admi Healt Health IT In IT Init itia iativ ives es Pamela King HIE Outreach Coordinator February 1, 2018 Ag Agen ency cy Hea Health IT In IT Initiatives es

571 views • 26 slides
Finding Opportunity in Crisis - An Innovators Perspective The Chinese use two brush strokes

Finding Opportunity in Crisis - An Innovators Perspective The Chinese use two brush strokes

Finding Opportunity in Crisis - An Innovators Perspective The Chinese use two brush strokes to write the word crisis. One brush stroke stands for danger; the other for opportunity. In a crisis, be aware of the danger -- but

639 views • 8 slides
Decision Support Project Team Engineering the System of Healthcare Delivery Engineering the System

Decision Support Project Team Engineering the System of Healthcare Delivery Engineering the System

Decision Support Project Team Engineering the System of Healthcare Delivery Engineering the System of Healthcare Delivery ESD 69 HST 926j HC 750 MIT Seminar on Health Care Systems Innovation ESD.69, HST.926j, HC.750 MIT Seminar on Health Care

584 views • 36 slides
Public Libraries and Healthy Communities Bobbi Newman Community Engagement And Outreach

Public Libraries and Healthy Communities Bobbi Newman Community Engagement And Outreach

Public Libraries and Healthy Communities Bobbi Newman Community Engagement And Outreach Coordinator National Network Of Libraries Of Medicine Greater Midwest Region Health Care Today Patients are now expected to be more involved in and to

822 views • 69 slides
Primary Care Practice supports in the Community Integrated Medical Home Niharika Khanna, MBBS,

Primary Care Practice supports in the Community Integrated Medical Home Niharika Khanna, MBBS,

Primary Care Practice supports in the Community Integrated Medical Home Niharika Khanna, MBBS, MD, DGO Associate Professor Family and Community Medicine University of Maryland School of Medicine Director Maryland Health Care Innovations

465 views • 13 slides
Broadband Access and Public Health: Legal and Policy Opportunities for Achieving Equitable

Broadband Access and Public Health: Legal and Policy Opportunities for Achieving Equitable

Broadband Access and Public Health: Legal and Policy Opportunities for Achieving Equitable Access September 3, 2020 | 1:00 2:30 PM ET Co-sponsored by: 1 How to Use WebEx Q & A 1. Open the Q&A panel 2. Select All

1.06k views • 50 slides
3/26/2014 Nothing to disclose Thyroid Nodules and Endocrine Incidentalomas UCSF Primary Care

3/26/2014 Nothing to disclose Thyroid Nodules and Endocrine Incidentalomas UCSF Primary Care

3/26/2014 Nothing to disclose Thyroid Nodules and Endocrine Incidentalomas UCSF Primary Care Update Hawaii April 10, 2014 Elizabeth J. Murphy, MD, DPhil Professor of Clinical Medicine University of California, San Francisco Chief, Division

541 views • 13 slides

More recommend