tuberculosis
play

Tuberculosis Mark Oette Klinik fr Allgemeine Innere Medizin, - PowerPoint PPT Presentation

Apr 05, 2023 •255 likes •508 views

Tuberculosis Mark Oette Klinik fr Allgemeine Innere Medizin, Gastroenterologie und Infektiologie Krankenhaus der Augustinerinnen, Kln Conflicts This presentation is free of financial interests Speech honoraria of the last 3

  1. Tuberculosis Mark Oette Klinik für Allgemeine Innere Medizin, Gastroenterologie und Infektiologie Krankenhaus der Augustinerinnen, Köln

  2. Conflicts • This presentation is free of financial interests • Speech honoraria of the last 3 years BMS Falk Gilead Heinen & Löwenstein Hitachi Krankenhäuser

  3. Tbc worldwide

  4. Europe: Transm issible Diseases Inzidence-based DALY/ 100.000, 2009-2013 (1.4 Mio, every 14th person) Cassini A. Eurosurveillance 2018; 23: pii= 17.00454

  6. Europe: Tbc Notification Rate

  7. Tuberculosis Incidence Germany (RKI 2018)

  8. Lung Tbc and Nationality (RKI 2015)

  9. Nationality: Italy

  10. Tuberculosis, Age, and Gender (RKI 2018)

  11. Diagnostics (RKI 2015)

  12. Mortality (RKI 2018)

  13. Resistance (RKI 2018)

  14. Resistance: Italy

  15. Resistance (RKI 2018)

  16. Lange C, et al. Respirology 2018; 23: 656-673

  17. Resistance (MDR)

  18. Europe: Tbc MDR-Rate

  21. Sequencing for Resistance Mutations • Evaluation of 5 software tools to predict resistance (n= 211), 2014 • Comparison with growth cultures/ phenotypic resistance testing • WGS: Illumina MiSec System • Software tools : PhyResSE, Mykrobe Predictor, TB Profiler, TGS-TB and KvarQ • Results: Sensitivity: 74-80% ; Specificity: > 95% Considerable variation between individual drugs Turnaround time (median): 5 vs. 19 days Van Beek J. Clin Microbiol Infect 2019; 25: 82-86

  22. Summary  In Germany approx. 5500 affected persons, slow decline  Epidemiology still driven by migrants  Resistance: Significant problem, rising (not in G)  Transmission of resistance  MDR: Relevant for survival  Resistance testing: Procession time suboptimal  Molecular resistance testing: New applications underway  The future: Resistance testing by NGS standard

  23. Thank you !

  24. Resistance

Download Presentation
Download Policy: The content available on the website is offered to you 'AS IS' for your personal information and use only. It cannot be commercialized, licensed, or distributed on other websites without prior consent from the author. To download a presentation, simply click this link. If you encounter any difficulties during the download process, it's possible that the publisher has removed the file from their server.

Recommend

What you need to know James Zoretic M.D., M.P.H. Regions 2 and 3 Director What is Tuberculosis?

What you need to know James Zoretic M.D., M.P.H. Regions 2 and 3 Director What is Tuberculosis?

Tuberculosis What you need to know James Zoretic M.D., M.P.H. Regions 2 and 3 Director What is Tuberculosis? Tuberculosis, (TB) is a communicable disease caused by the Mycobacterium tuberculosis bacillus Slow growing germ Spread by

635 views • 29 slides
What you need to know James Zoretic M.D., M.P.H. Regions 2 and 3 Director What is Tuberculosis?

What you need to know James Zoretic M.D., M.P.H. Regions 2 and 3 Director What is Tuberculosis?

Tuberculosis What you need to know James Zoretic M.D., M.P.H. Regions 2 and 3 Director What is Tuberculosis? Tuberculosis, (TB) is a communicable disease caused by the Mycobacterium tuberculosis bacillus Slow growing germ Spread by

654 views • 30 slides
Tuberculosis in the United States 1993 2018* National Tuberculosis Surveillance System

Tuberculosis in the United States 1993 2018* National Tuberculosis Surveillance System

National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Division of Tuberculosis Elimination Tuberculosis in the United States 1993 2018* National Tuberculosis Surveillance System *Updated as of June 6, 2019 Reported

678 views • 45 slides
P RIS Bettencourt TUBERCULOSIS IS A WORLDWIDE DISEASE 1 3 OF THE WORLD POPULATION HAS

P RIS Bettencourt TUBERCULOSIS IS A WORLDWIDE DISEASE 1 3 OF THE WORLD POPULATION HAS

P RIS Bettencourt TUBERCULOSIS IS A WORLDWIDE DISEASE 1 3 OF THE WORLD POPULATION HAS LATENT TUBERCULOSIS MILLION 1.3 DEATHS PER YEAR FIGHT TUBERCULOSIS MODERN WEAPONS with target detect infjltrate sabotage gender study INFILTRATE

725 views • 38 slides
TUBERCULOSIS IN NEW YORK CITY, 2017 New York City Bureau of Tuberculosis Control TUBERCULOSIS

TUBERCULOSIS IN NEW YORK CITY, 2017 New York City Bureau of Tuberculosis Control TUBERCULOSIS

TUBERCULOSIS IN NEW YORK CITY, 2017 New York City Bureau of Tuberculosis Control TUBERCULOSIS CASES AND RATES, 1 NEW YORK CITY, 1983-2017 Number of cases Rate 4500 60 4000 50 3500 Rate per 100,000 Number of cases 3000 40 2500 7.5 per

468 views • 27 slides
Florida, 2016 Tuberculosis Control Section Division of Disease Control and Health Protection

Florida, 2016 Tuberculosis Control Section Division of Disease Control and Health Protection

Tuberculosis Florida, 2016 Tuberculosis Control Section Division of Disease Control and Health Protection 4052 Bald Cypress Way, Bin A-20 Tallahassee, FL 32399 http://www.floridahealth.gov/diseases-and-conditions/tuberculosis Division of

491 views • 14 slides
Technological & Financial Analysis of a Carbohydrate Vaccine for Tuberculosis Presented by:

Technological & Financial Analysis of a Carbohydrate Vaccine for Tuberculosis Presented by:

Technological & Financial Analysis of a Carbohydrate Vaccine for Tuberculosis Presented by: Melissa Martin Erica Clemente-Harl Tuberculosis Currently: Projected: ! Leading cause of death in ! 37,800,000 of current HIV developing world

1.2k views • 71 slides
Introduction Excluding HIV/AIDS, Tuberculosis (TB) is responsible for more deaths worldwide than

Introduction Excluding HIV/AIDS, Tuberculosis (TB) is responsible for more deaths worldwide than

Tuberculosis: the hidden disease Introduction Excluding HIV/AIDS, Tuberculosis (TB) is responsible for more deaths worldwide than any other infectious agent, with approximately 1.4 million global mortalities in 2011 (WHO, 2012). Although TB

579 views • 23 slides
After more than one decade of the epoch making discovery of the tuberculosis agent and more than

After more than one decade of the epoch making discovery of the tuberculosis agent and more than

After more than one decade of the epoch making discovery of the tuberculosis agent and more than fifty years of the introduction of the efficient antituberculotics, tuberculosis is still the leading agent for the mortality among adults all

347 views • 19 slides
CONTROL PROFESSIONAL Alawode Oladele, MD, MPH Elements of our Tuberculosis Control Program X-ray

CONTROL PROFESSIONAL Alawode Oladele, MD, MPH Elements of our Tuberculosis Control Program X-ray

TUBERCULOSIS FOR THE INFECTION CONTROL PROFESSIONAL Alawode Oladele, MD, MPH Elements of our Tuberculosis Control Program X-ray Targeted testing/ LTBI treatment Pharmacy Clinical Inpatient care Medical evaluation Services and follow-up

763 views • 34 slides
Showcasing some research in Genomics and Bioinformatics Sacchettini Lab: Research Tuberculosis

Showcasing some research in Genomics and Bioinformatics Sacchettini Lab: Research Tuberculosis

Showcasing some research in Genomics and Bioinformatics Sacchettini Lab: Research Tuberculosis What is it? Tuberculosis (TB) is an infectious disease caused by a bacterium. Approximately two billion people, one third of the Earth's

410 views • 14 slides
Improved diagnosis of extrapulmonary tuberculosis by antigen detection using

Improved diagnosis of extrapulmonary tuberculosis by antigen detection using

Improved diagnosis of extrapulmonary tuberculosis by antigen detection using immunochemistry-based assay Tehmina Mustafa Overview Introduction: extrapulmonary tuberculosis (TB) & diagnostic challenges New diagnostic method

362 views • 25 slides
Mycobacterium tuberculosis Mycobacterium tuberculosis Rv2224c modulates innate Rv2224c modulates

Mycobacterium tuberculosis Mycobacterium tuberculosis Rv2224c modulates innate Rv2224c modulates

Mycobacterium tuberculosis Mycobacterium tuberculosis Rv2224c modulates innate Rv2224c modulates innate immune responses immune responses Jyothi Rengarajan, Elissa Murphy, Arnold Park, Arnold Park, Cassandra L. Krone, Erik C. Hett, Barry R.

616 views • 37 slides
1 Scanning electron micrograph of Mycobacterium tuberculosis 2 3 Sarah Stanley Deb Hung 4

1 Scanning electron micrograph of Mycobacterium tuberculosis 2 3 Sarah Stanley Deb Hung 4

Brain Blood vessels Lungs Heart Pancreas Liver Kidney Cartilage Bone Muscle 1 Scanning electron micrograph of Mycobacterium tuberculosis 2 3 Sarah Stanley Deb Hung 4 1.7 million deaths/year Tuberculosis 9.2 million new

439 views • 16 slides
Changing the Conversation: Human Rights and the Power of Words in Tuberculosis Care July 16,

Changing the Conversation: Human Rights and the Power of Words in Tuberculosis Care July 16,

Changing the Conversation: Human Rights and the Power of Words in Tuberculosis Care July 16, 2015 Sponsored by Global Tuberculosis Institute Rutgers, The State University of New Jersey Housekeeping Faculty Jane Carter, MD President, The

687 views • 36 slides
Tuberculosis in Nunavut, Canada Dora Maria Carbonu, EdD, MN, RN 24 th Sigma Theta Tau

Tuberculosis in Nunavut, Canada Dora Maria Carbonu, EdD, MN, RN 24 th Sigma Theta Tau

Tuberculosis in Nunavut, Canada Dora Maria Carbonu, EdD, MN, RN 24 th Sigma Theta Tau International Nursing Research Congress Prague, Czech Republic July 22 26, 2013 TUBERCULOSIS IN NUNAVUT, CANADA One Community's Initiative To Promote

733 views • 48 slides
Bay of Plenty Environment Forum 2015 Our connected waterways Dr Mike Joy Ecology - Institute of

Bay of Plenty Environment Forum 2015 Our connected waterways Dr Mike Joy Ecology - Institute of

Bay of Plenty Environment Forum 2015 Our connected waterways Dr Mike Joy Ecology - Institute of Agriculture & Environment Massey University Palmerston North Why should we care about our freshwater lakes and streams they are 100% pure

480 views • 31 slides
Dr Mike Joy Ecology - Institute of Agriculture & Environment Massey University Palmerston

Dr Mike Joy Ecology - Institute of Agriculture & Environment Massey University Palmerston

Dr Mike Joy Ecology - Institute of Agriculture & Environment Massey University Palmerston North 1. Some motivation - why we should care (the sad reality - freshwater in NZ) 2. Why what you are doing is so important 3. What healthy

593 views • 23 slides
Disease Modelling and Handling the Presentation of Large Datasets Presented by: Nick Hill

Disease Modelling and Handling the Presentation of Large Datasets Presented by: Nick Hill

Disease Modelling and Handling the Presentation of Large Datasets Presented by: Nick Hill GIS/Developer Institute of Environmental Science and Research (ESR) Contents Introduction HAIFA Project Overview Model Presentation

505 views • 19 slides
Food Safety Regulation and Litigation: Minimizing the Risk of Product Liability Claims Mastering

Food Safety Regulation and Litigation: Minimizing the Risk of Product Liability Claims Mastering

Presenting a live 90-minute webinar with interactive Q&A Food Safety Regulation and Litigation: Minimizing the Risk of Product Liability Claims Mastering the Standards for Fault, Causation and Damages in Foodborne Illness Litigation

1.38k views • 101 slides
Cavernous sinus syndrome due Kalyan B. Bhattacharyya, Saurabh Rai 1 to skull base metastasis: A

Cavernous sinus syndrome due Kalyan B. Bhattacharyya, Saurabh Rai 1 to skull base metastasis: A

[Downloaded free from http://www.neurologyindia.com on Friday, April 20, 2018, IP: 103.227.71.66] Letters to Editor Figure 2: Plain computed tomography scan of the brain showing symmetrical hypodensity in the white matuer and subcortjcal cysts in

456 views • 3 slides
Presented by: Lisa Kuuttila CEO & Chief Economic Development Officer 801 University Blvd.

Presented by: Lisa Kuuttila CEO & Chief Economic Development Officer 801 University Blvd.

Presented by: Lisa Kuuttila CEO & Chief Economic Development Officer 801 University Blvd. SE, Suite 101 Albuquerque, NM 87106 (505) 272-7900 kuuttila@stc.unm.edu To foster a Rainforest in the Desert, STC.UNM nurtures innovation and

688 views • 39 slides
Case Study: Environmental Public Health to improve quality of life. Professor George Karani,

Case Study: Environmental Public Health to improve quality of life. Professor George Karani,

Case Study: Environmental Public Health to improve quality of life. Professor George Karani, Cardiff Metropolitan University School of Health Sciences. Presentation at East Africa through the lens: Perspectives from Kenya and Tanzania event,

370 views • 14 slides
Facebook Friend Wheel By: Mollie Breen and Audrey Vernick Corresponding Communication Matrix

Facebook Friend Wheel By: Mollie Breen and Audrey Vernick Corresponding Communication Matrix

Facebook Friend Wheel By: Mollie Breen and Audrey Vernick Corresponding Communication Matrix Degree Centrality Katie Breen: 12 (row 9) Patrick Rollo: 12 (row 10) Corresponding Communicatio n Matrix Degree Centrality Annabel

571 views • 13 slides

More recommend