Stem cell and cell therapeutics research in Lithuania Bernardas Morkunas Head of Business Development
Lithuanian biotech Biotechnology is considered as one of 2014-2020 Smart Specialisation priority fields in Lithuania Large and fast growing Export oriented Key exports • Revenue $150M+ • Around 90% of revenue comes • Pharmaceutical proteins • CAGR 20% from exports • Enzymes and nucleic acids • 10+ notable companies • Industry export CAGR of 16.1% • Reagents and devices for • Overall Lithuanian export growth molecular bio 10.2%
Company highlights Several highly successful Lithuanian biotechnology companies Sicor Biotech UAB Fermentas UAB Acquired by Teva Pharmaceuticals Acquired by ThermoFisher Revenue €50-100M Revenue €50-100M Develops and produces recombinant Develops and produces enzymes and other biopharmaceuticals products for life science research and diagnostics. Was headed by Prof. V. A. Bumelis, now CEO of Biotechpharma UAB Products are widely used worldwide.
Biotech startups Lithuania is a place for a large number of biotech startups
Valleys, business clusters, and incubators Valley, MTEP Funding, location directions million, $ Biotechnology Santara Valley Innovative Medical Technologies 125,51 Vilnius Molecular Medicine Laser and Light technologies Sunrise Valley Material Sciences 122,22 Vilnius Nanotechnologies Santaka Valley Sustainable chemistry and pharmaceuticals 96,52 Kaunas Future Power Engineering Nemunas Valley Agro biotechnology 72,16 Kaunas Food technology Maritime Valley Marine Environment 78,46 Klaipėda Coastal research
Santara valley Sicor Biotech / TEVA Biotechpharma BOD Group MOOG Centre for Innovative Medicine (CIM)
Stem Cell Research Center Key People Algirdas Ziogas, PhD Dziugas Paulauskas, PhD Kristina Mateikiene Head of R&D Managing Director Project manager Vilnius University (Molecular Genetics) Kaunas Medical University (Pharmacy) Kaunas Medical University (Pharmacy) University of Zurich (PhD in Biochemistry) Institute of Biotechnology (PhD in 10 years as a consultant and manager 12 years as PostDoc in U. of Zurich, U. of Biochemistry) in pharmacy Bern, and University Hospital Zurich 10 years of research experience 21 years as a manager Life Sciences
What is Stem Cell RC? Stem cell and cell therapeutics research center and contract manufacturing organisation, part of Northway group, Stem Cell Cluster manager Healthcare holding Fields of expertise • Biopharmaceuticals Stem cell cluster Fields of expertise • Private healthcare Related to Manages • Cell Services 21 companies: therapeutics • Research 6 hospitals • • Stem cells • Contract manufacturing 10+ R&D institutions • Services organization • Research • Healthcare • Contract manufacturing organisation
Stem Cell and Regenerative Cluster CDMO, CRO, clinical and pre-clinical research under one roof Production Biosimilars, cell therapy Pre-clinical Clinical Animal models, toxicity, Clinical trials, pre- etc approval therapies
Selected Stem Cell Cluster member profiles Biotechpharma VU Santariskiu hospital Northway medical centers • Biopharmaceuticals CDMO • Leading clinical hospital • Private healthcare • BigPharma and Biotech clients • 4’000 staff • 200 staff • 100 staff • Specialist in numerous fields • Wide array of services • 450 sqm cGMP (A-D) • National medical R&D center • Highly respected healthcare • State of the art R&D laboratories Kardivita Lirema • Cardio-oriented healthcare • Optometrist R&D and healthcare • 20 staff • 40 staff • Highly specialized, both invasive • Network of several center across and non-invasive approaches Lithuania
Stem Cell RC facilities Cluster partners Mokslininku Str. 4 S. Zukausko Str. 21 • 450 sqm cGMP (Class A-D) • 5 R&D labs • 180 sqm cGMP (Class C, D) • Labs for biotech and medicine • Admin space • Proximity with operating theatre • 4’500 healthcare staff • Patient wards • 500 scientific staff • Co-location with private hospital
Facilities and laboratories (Biotechpharma)
Research staff Access to 30+ qualified R&D staff and high potential growth opportunities Algirdas Ziogas, PhD Head of R&D Staff On demand staff Lithuanian Talent pool 11 researchers inc. 3 PhDs Access to 300+ researchers and Medical 1’000+ life sciences graduates per annum Doctors through Stem Cell Cluster
Current research activities Stem cell Development of New biomaterials and analysis preclinical models metabolomics approaches Special emphasis on: Special emphasis on: Special emphasis on: Endothelial progenitor cells Mass spectrometry and metabolite Wound healing and angiogenesis • • • Mesenchymal stem cells (umbilical studies Heart repair • • cord, adipose tissue, bone marrow) Therapeutic protein immobilization • Chondrocytes strategies • Cancer stem cells • iPSCs •
R&D partnerships Looking for partnerships for Horizon 2020, Eureka, Eurostars, and others
Contact us Bernardas Morkunas Head of Business Development Bernardas.morkunas@biotechpharma.lt +370 678 07361 +370 5 2195254
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