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Simulation of Cardiac Ischemia and Arrhythmias - - PDF document
Simulation of Cardiac Ischemia and Arrhythmias - - PDF document
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SLIDE 3
Simulation of Ischemia Ischemia
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Supply Demand
Coronary Supply versus Demand
Supply Demand
Coronary Supply versus Demand
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Supply Demand
Ischemia!
Coronary Supply versus Demand
Supply Demand
Coronary Supply versus Demand
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Supply Demand
Ischemia!
Coronary Supply versus Demand Heart Attacks and the ECG
Continuous monitoring:
! 30-50% error rate ! Lead locations unclear,
suboptimal
! Tracks changes dynamically
Stress testing
! Low sensitivity/specificity ! Thresholds variable ! Tracks changes during stress
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LV
Ischemic Zone
RV
Hopenfeld et al. JCE, 15:1200, 2004
Blood Pump
Shome et al. IEEE EMBS, 2004
Experiments and Simulations Simulation of Ischemia
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Model Making
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The Tools
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40% Transmural 70% Transmural 90% Transmural
A B
Comparing Models to Experiments
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The Goal
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Simulation of Atrial Arrhythmias Fibrosis Linked to AF
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Fibrosis Linked to AF Modeling Approach
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Extracellular Intracellular
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