SLIDE 11 Implementation Science
- Tobacco, obesity, physical activity
- Screening: CRC, breast, lung
Lynch Syndrome
- CRC tumor testing for MMR, MSI
(Hampel H, et al. JNCCN 2010; Hampel H, et al. JCO 2008; Hampel H, et al. NEJM 2005)
- To identify LS families (for intensive surveillance) and MSI+ patients (e.g., anti-PD-1; Le, et al. NEJM 2015)
- Recommended by EGAPP, NCCN, USMTF on CRC, ACG, and SGO/ACOG
- Data supporting endometrial cancer in GOG/NRG (Goodfellow PJ, et al. J Clin Oncol 2015 Dec)
Mar 2012
HPV Vaccines
Boys and girls age 11-12, three (3) doses (CDC, ACIP) Utilization: 36% girls, 14% boys (3 doses); even lower in Hispanics, Blacks, poor; healthcare disparity even greater globally (> 600,000 cancer cases/year) Barriers
- Limited understanding
- Missed additional doses
- Cost / safety concerns
Roadmap to increased vaccination uptake
- Shift focus from behavior associated with
infection to preventing major cancers
- Further study of 1 vs. 3 doses
American Academy of Family Physicians American Academy of Pediatrics American College of Obstetricians and Gynecologists American College of Physicians Centers for Disease Control and Prevention Immunization Action Coalition American Cancer Society American College of Obstetrics and Gynecology American Dental Association American Head and Neck Society American Nurses Association American Pharmacists Association Association of Immunization Managers Society for Adolescent Medicine Society of Gynecologic Oncology
