SCEPTER-III Clinical Trials to Evaluate Patient-Centered Outcomes - - PowerPoint PPT Presentation

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Dec 22, 2023 249 likes •388 views

SCEPTER-III Clinical Trials to Evaluate Patient-Centered Outcomes of Sedation in Mechanically Ventilated Patients in the Adult ICU March 28-29, 2019 Washington, DC Pre-clinical testing Compound Discovery Phase 4 post marketing clinical

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Clinical Trials to Evaluate Patient-Centered Outcomes of Sedation in Mechanically Ventilated Patients in the Adult ICU March 28-29, 2019 Washington, DC

SCEPTER-III

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Phase 4 post marketing clinical trials Compound Discovery Pre-clinical testing Phase 1 -3 clinical trials FDA Approval

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Outcomes Data Collection (GCP) Clinical Trial Design

FDA Academic Clinical Researcher Pharma Public Practicing Clinician Health Care Systems

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Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research (SCEPTER)

Two systematic reviews on Procedural Sedation

(adult and pediatric) published

Two consensus recommendations published on

Procedural Sedation (Efficacy and Safety)

Consensus conference on sedation for Adult ICU

patients in March

Future conference on sedation for Pediatric ICU

patients

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https://www.openanesthesia.org/article-of-the-month/

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Healthcare Quality Domains

Safe Timely Patient centered Effective Efficient Equitable

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Comfortable
No anxiety
No unpleasant recall
Prompt return to

baseline

No side effects (e.g.

PONV)

Rapid recovery & D/C
Optimal procedure
utcome
No airway

intervention or CV instability

Ease of sedation
Consistent sedation
Ease of procedure
Ideal conditions for

procedure

Patient Clinician

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Re Reade MC, Fi Finfer er S.

S. N En

Engl J J Med 2014;370:444-454. 454.

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