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Safety Considerations in Safety Considerations in Recombinant DNA Research Recombinant DNA Research with Pathogenic Viruses with Pathogenic Viruses This meeting and development of the This meeting and development of the Points to Consider is


  1. Safety Considerations in Safety Considerations in Recombinant DNA Research Recombinant DNA Research with Pathogenic Viruses with Pathogenic Viruses This meeting and development of the This meeting and development of the Points to Consider is the beginning of an Points to Consider is the beginning of an ongoing process necessary to keep IBCs up to ongoing process necessary to keep IBCs up to date with the scientific and medical advances date with the scientific and medical advances they use to inform their containment decisions. they use to inform their containment decisions.

  2. Safety Considerations in Safety Considerations in Recombinant DNA Research Recombinant DNA Research with Pathogenic Viruses with Pathogenic Viruses The Points to Consider are meant to be a The Points to Consider are meant to be a resource for IBCs not only for the infectious resource for IBCs not only for the infectious agents discussed at this meeting, but also to agents discussed at this meeting, but also to provide a framework for their deliberations of provide a framework for their deliberations of containment issues attendant to research with containment issues attendant to research with emerging infectious agents. emerging infectious agents.

  3. Safety Considerations in Safety Considerations in Recombinant DNA Research Recombinant DNA Research with Pathogenic Viruses with Pathogenic Viruses � Research into viral virulence mechanisms and the development of vaccines and antiviral drugs are public health priorities. � While this research is of critical importance, it is equally important that the research be performed responsibly to protect the health of laboratory researchers and the public.

  4. Overarching Principals Overarching Principals � A process needs to be established A process needs to be established � whereby I BCs can share information whereby I BCs can share information and their experiences in determining and their experiences in determining appropriate biosafety containment appropriate biosafety containment levels. levels. � Education, formal training, and Education, formal training, and � mentoring of personnel who work with mentoring of personnel who work with infectious agents is paramount to infectious agents is paramount to ensure appropriate biosafety practices ensure appropriate biosafety practices are followed. are followed. � Appropriate I nstitutional support and Appropriate I nstitutional support and � oversight is necessary for I BCs to oversight is necessary for I BCs to function optimally. function optimally.

  5. Future Efforts to help Future Efforts to help I BCs and I nvestigators I BCs and I nvestigators � OBA has and will continue to provide OBA has and will continue to provide � educational programs and assistance educational programs and assistance to I BCs. to I BCs. th revision of the Biosafety in � The 5 The 5 th revision of the Biosafety in � Microbiological and Biomedical Microbiological and Biomedical Laboratories (BMBL) is in progress and Laboratories (BMBL) is in progress and will provide specific guidance for will provide specific guidance for influenza and is a collaborative process influenza and is a collaborative process between the HHS and USDA. between the HHS and USDA.

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