qFIT PILOT A NEW TEST FOR RULING OUT COLORECTAL CANCER Dr Ed Seward - - PowerPoint PPT Presentation

▶
qfit pilot
SMART_READER_LITE
LIVE PREVIEW

qFIT PILOT A NEW TEST FOR RULING OUT COLORECTAL CANCER Dr Ed Seward - - PowerPoint PPT Presentation

Feb 22, 2024 257 likes •360 views

qFIT PILOT A NEW TEST FOR RULING OUT COLORECTAL CANCER Dr Ed Seward UCLH Cancer Collaborative 1 COLORECTAL CANCER AT A GLANCE 2 nd leading 90% chance of 260,000 4% of cause of successful urgent GP patients cancer treatment if referrals

slide-1
SLIDE 1

qFIT PILOT

A NEW TEST FOR RULING OUT COLORECTAL CANCER

Dr Ed Seward UCLH Cancer Collaborative

1

slide-2
SLIDE 2

COLORECTAL CANCER AT A GLANCE

2

2nd leading cause of cancer deaths in UK 260,000 urgent GP referrals for suspected cancer 90% chance of successful treatment if diagnosed early 4% of patients undergo colonoscopy have cancer

slide-3
SLIDE 3

STOOL TESTS - FOBT & qFIT

3

  • Cheap and easy to use stool test to detect hidden blood as an

indicator of colorectal cancer

  • Guaiac Faecal Occult Blood Test (FOBT)
  • Bowel cancer screening
  • Reaction of haemoglobin with guaiac resin
  • Only qualitative
  • High false positives – low sensitivity
  • 3 samples, dietary restrictions
  • Quantitative Faecal Immunochemical Test (qFIT)
  • Uses specific antibodies against human haemoglobin
  • Much more sensitive - 90%< NPV
  • Quantitative
  • One sample
  • Specific to human blood – no dietary restrictions
slide-4
SLIDE 4

qFIT

4

  • 4 main applications of qFIT

Asymptomatic

Bowel Screening Programme RULE-IN TEST

Symptomatic

Low risk patients – ongoing NICE consultation High risk patients – qFIT Pilot – RULE-OUT TEST

Asymptomatic

Surveillance

slide-5
SLIDE 5

qFIT PILOT

5

  • Largest pilot led by UCLH Cancer Collaborative
  • Reliable ‘rule-out’ test of significant bowel disease for

symptomatic patients in primary care?

  • 6 month pilot launching March 2017
  • 6 Trusts & 33 GP practices across NCL, NEL, WE
  • qFIT pack is handed out as an addition to 2ww pathway
  • Minimum of 2000 samples
  • early adoption by NHS supported by NICE
slide-6
SLIDE 6

Queen’s Hospital

11 Hospitals in 6 NHS Trusts

Barnet Hopistal Chase Farm Hospitals King George Hospital Newham University Hospital North Middlesex Hospital Princess Alexandra Hospital Queen’s Hospital Royal Free Hospital The Royal London Hospital University College Hospital Whipss Cross University Hospital

33 GP practices at 8 CCGs

Barking & Dagenham CCG Barnet CCG City and Hackney CCG Havering CCG Islington CCG Newham CCG Redbridge CCG West Essex CCG

GEOGRAPHICAL AREA

6

slide-7
SLIDE 7

qFIT PILOT SET UP

7

slide-8
SLIDE 8

qFIT – EXPECTED BENEFITS

8

  • Improved patient experience
  • Reduce the number of colonoscopies by approx. 40%

freeing up endoscopy capacity for other programmes NEXT STEPS

  • NHS qFIT group
  • Phase II – test uptake & sample collection methods +

collaborations

  • Evaluating GP & patient acceptability
  • Cost-benefit analysis
slide-9
SLIDE 9

QUESTIONS?

edward.seward@uclh.nhs.uk michael.machesney@bartshealth.nhs.uk helga.laszlo@nhs.net claire.levermore@uclh.nhs.uk

9