prion diseases
play

Prion diseases Mabbott et al. Nature Reviews Microbiology advance - PowerPoint PPT Presentation

Nov 12, 2023 •273 likes •401 views

Prion diseases Mabbott et al. Nature Reviews Microbiology advance online publication; published online 06 February 2006 | doi:10.1038/nrmicro1346 Infected brains CJD - human BSE - cow kuru - human BSE vCJD Infected animals Incidence of

  1. Prion diseases Mabbott et al. Nature Reviews Microbiology advance online publication; published online 06 February 2006 | doi:10.1038/nrmicro1346

  2. Infected brains CJD - human BSE - cow kuru - human

  3. BSE  vCJD Infected animals Incidence of entering food supply vCJD

  4. Structure of PrP

  5. PrP c PrP Sc

  6. Models for conversion from PrP c to PrP Sc

  7. Seeding models of prion propagation

  8. Mutations in Prnp associated with human TSEs

  9. Role of cytoplasmic PrP in neurodegenerative disease

  10. Lee et al., 2000

  11. Olsson et al., 1995

Download Presentation
Download Policy: The content available on the website is offered to you 'AS IS' for your personal information and use only. It cannot be commercialized, licensed, or distributed on other websites without prior consent from the author. To download a presentation, simply click this link. If you encounter any difficulties during the download process, it's possible that the publisher has removed the file from their server.

Recommend

Progress in detecting prions and diagnosing prion diseases Byron Caughey TSE/Prion Biochemistry

Progress in detecting prions and diagnosing prion diseases Byron Caughey TSE/Prion Biochemistry

Progress in detecting prions and diagnosing prion diseases Byron Caughey TSE/Prion Biochemistry Section, LPVD, Rocky Mountain Labs Amyloid plaque Pam Caughey Transmissible spongiform encephalopathies (prion) diseases Slow, fatal,

621 views • 24 slides
Prion Disease Overview What is a prion? pro tein and in fectious - ion (infectious, e.g.

Prion Disease Overview What is a prion? pro tein and in fectious - ion (infectious, e.g.

Prion Disease Overview What is a prion? pro tein and in fectious - ion (infectious, e.g. virion ) No nucleic acid (e.g., DNA, RNA, building blocks of life) Non-degradable by typical sterilization PrP: prion protein PrP C :

741 views • 18 slides
Protein polymerization simulation for amyloid diseases (Prion, Alzheimer s) Marie Doumic

Protein polymerization simulation for amyloid diseases (Prion, Alzheimer s) Marie Doumic

Protein polymerization simulation for amyloid diseases (Prion, Alzheimer s) Marie Doumic Let's imagine the future 1 November 9th, 2012 Outline q A brief overview: The mathematical context The biological motivation and main

432 views • 26 slides
OF HUMAN PRION DISEASES Richard Knight NCJDRSU / CCBS University of Edinburgh Scotland

OF HUMAN PRION DISEASES Richard Knight NCJDRSU / CCBS University of Edinburgh Scotland

DIAGNOSIS & TREATMENT OF HUMAN PRION DISEASES Richard Knight NCJDRSU / CCBS University of Edinburgh Scotland OUTLINE SOME GENERAL POINTS ABOUT DIAGNOSIS RECENT DIAGNOSTIC DEVELOPMENTS SOME GENERAL POINTS ABOUT TREATMENT TREATMENT

999 views • 77 slides
The Centers for Disease Control and Prevention Report: Prion Disease Activities at CDC Ryan A.

The Centers for Disease Control and Prevention Report: Prion Disease Activities at CDC Ryan A.

The Centers for Disease Control and Prevention Report: Prion Disease Activities at CDC Ryan A. Maddox, PhD Epidemiologist 2015 CJD Foundation Family Conference July 12, 2015 National Center for Emerging and Zoonotic Infectious Diseases

533 views • 34 slides
Ge Gene netic tic Di Diagnosi agnosis and and Pr Prion on Di Dise seases ases Bradley

Ge Gene netic tic Di Diagnosi agnosis and and Pr Prion on Di Dise seases ases Bradley

Pr Pre-Im Implant plantation ation Ge Gene netic tic Di Diagnosi agnosis and and Pr Prion on Di Dise seases ases Bradley Kalinsky, MD Amanda Kalinsky, RN, BSN Disclaimer: We are not Prion researchers. We are not Reproductive

674 views • 30 slides
CJD Foundation Conference Kevin Keough PhD FCAHS ICD.D Executive Director Alberta Prion Research

CJD Foundation Conference Kevin Keough PhD FCAHS ICD.D Executive Director Alberta Prion Research

CJD Foundation Conference Kevin Keough PhD FCAHS ICD.D Executive Director Alberta Prion Research Institute July 12, 2015 www.prioninstitute.ca 1 Alberta Prion Research Institute Created in 2005 in response to the 2003 BSE crisis

171 views • 5 slides
Structure of the National Prion Disease Pathology Surveillance Center (NPDPSC) Presented by Jiri

Structure of the National Prion Disease Pathology Surveillance Center (NPDPSC) Presented by Jiri

Departments of Pathology, Neurology, and National Prion Disease Pathology Surveillance Center New Goals and Organizational Structure of the National Prion Disease Pathology Surveillance Center (NPDPSC) Presented by Jiri G. Safar CJD Fdn

343 views • 11 slides
Computational design of a circular RNA with prion-like behavior Stefan Badelt 1 , Christoph Flamm

Computational design of a circular RNA with prion-like behavior Stefan Badelt 1 , Christoph Flamm

Computational design of a circular RNA with prion-like behavior Stefan Badelt 1 , Christoph Flamm 1 and Ivo L. Hofacker 1 , 2 { stef,xtof,ivo } @tbi.univie.ac.at 1 Institute for Theoretical Chemistry , University of Vienna, W ahringerstrae

786 views • 21 slides
Computational design of a circular RNA with prion-like behavior Stefan Badelt 1 , Christoph Flamm

Computational design of a circular RNA with prion-like behavior Stefan Badelt 1 , Christoph Flamm

Computational design of a circular RNA with prion-like behavior Stefan Badelt 1 , Christoph Flamm 1 and Ivo L. Hofacker 1 , 2 { stef,xtof,ivo } @tbi.univie.ac.at 1 Institute for Theoretical Chemistry , University of Vienna, W ahringerstrae

188 views • 18 slides
VACCINE PREVENTABLE DISEASES: VACCINE PREVENTABLE DISEASES: VACCINE PREVENTABLE DISEASES:

VACCINE PREVENTABLE DISEASES: VACCINE PREVENTABLE DISEASES: VACCINE PREVENTABLE DISEASES:

VACCINE PREVENTABLE DISEASES: VACCINE PREVENTABLE DISEASES: VACCINE PREVENTABLE DISEASES: VACCINE PREVENTABLE DISEASES: IMMUNIZATION, EXEMPTIONS, AND OUR COMMUNITY BY: MATTHEW TOWN, PHD, MPH DISEASE CONTROL AND PREVENTION PROGRAM SUPERVISOR

1.04k views • 27 slides
Globalization of Infectious Diseases Globalization of Infectious Diseases Origin of Some

Globalization of Infectious Diseases Globalization of Infectious Diseases Origin of Some

Globalization of Infectious Diseases Globalization of Infectious Diseases Origin of Some Infectious Disease Agents Ebola West Nile Lassa Norwalk Coxsackie Lyme Hanta Ecological Factors Influencing the Emergence of Infectious Diseases

529 views • 50 slides
Rheumatological Rheumatological Diseases Diseases Rheumatological Rheumatological Diseases

Rheumatological Rheumatological Diseases Diseases Rheumatological Rheumatological Diseases

Rheumatologic Diseases Rheumatologic Diseases 6/23/2011 6/23/2011 Rheumatological Rheumatological Diseases Diseases Rheumatological Rheumatological Diseases Diseases Disease Disease Autoantibody Autoantibody Systemic Lupus

517 views • 23 slides
Honey Bee Pests and Diseases Dale McMahan Honey Bee Pests and Diseases Pests Diseases

Honey Bee Pests and Diseases Dale McMahan Honey Bee Pests and Diseases Pests Diseases

Honey Bee Pests and Diseases Dale McMahan Honey Bee Pests and Diseases Pests Diseases American Foul Brood Varroa Mite European Foul Brood Trachael Mite Nosema Wax Moth Chalk Brood Small Hive Beetle Sac Brood

665 views • 27 slides
Mortality from Diseases of Respiratory System (URT, LRT and ORD) in Delhi The URT diseases

Mortality from Diseases of Respiratory System (URT, LRT and ORD) in Delhi The URT diseases

Mortality from Diseases of Respiratory System (URT, LRT and ORD) in Delhi The URT diseases steeply increase for Delhi after 2009 ORD mortality: high for Delhi (major contributor Pneumonia) 600 1200 3000 500 1000 2500 400 800 2000

633 views • 15 slides
Centre for Neuromuscular Diseases Queen Square Centre for Neuromuscular Diseases

Centre for Neuromuscular Diseases Queen Square Centre for Neuromuscular Diseases

Centre for Neuromuscular Diseases Queen Square Centre for Neuromuscular Diseases Multidisciplinary Centre for patients with neuromuscular diseases combining patient care, training and research: Services for over 5000 patients per year

83 views • 7 slides
Introduc*on Our Mission & What we do Our Core

Introduc*on Our Mission & What we do Our Core

OUTLINE Introduc*on Our Mission & What we do Our Core Areas Partners Geographical & Sector Distribu*on RMF In-Depth INTRODUCTION

364 views • 34 slides
Statewide Healthcare Innovation Plan (SHIP) Presentation Topics 1. Healthcare Transformation in

Statewide Healthcare Innovation Plan (SHIP) Presentation Topics 1. Healthcare Transformation in

Statewide Healthcare Innovation Plan (SHIP) Presentation Topics 1. Healthcare Transformation in Idaho Statewide Healthcare Innovation Plan (SHIP) Patient-Centered Medical Home (PCMH) Timeline 3. Medical-Health Neighborhood

644 views • 27 slides
Our Health and Wellness BC First Nations Perspective on Wellness recognizes that health and

Our Health and Wellness BC First Nations Perspective on Wellness recognizes that health and

Our Health and Wellness BC First Nations Perspective on Wellness recognizes that health and wellness belongs to human beings and is an outcome of many interrelated factors Our vision of health and wellness comes from the ancestors and is

838 views • 55 slides
Serious Illness Care in Primary Care Jonathan Fischer, MD Duke Community and Family Medicine

Serious Illness Care in Primary Care Jonathan Fischer, MD Duke Community and Family Medicine

Serious Illness Care in Primary Care Jonathan Fischer, MD Duke Community and Family Medicine Duke Hospice and Palliative Care Duke Population Health Management Office Touch on Intersection of Palliative and Primary Care What are some

558 views • 37 slides
Reaching the goals of personalized (P4) medicine: what hills are left to climb? Predictive,

Reaching the goals of personalized (P4) medicine: what hills are left to climb? Predictive,

Reaching the goals of personalized (P4) medicine: what hills are left to climb? Predictive, Personalized, Preventive and Participatory Lee Hood Institute for Systems Biology, Seattle In 10 years P4 Medicine will Generate Billions of Data

779 views • 64 slides
Chronic Wasting Disease in Southeast Minnesota Drs. Michelle Carstensen and Lou Cornicelli

Chronic Wasting Disease in Southeast Minnesota Drs. Michelle Carstensen and Lou Cornicelli

Chronic Wasting Disease in Southeast Minnesota Drs. Michelle Carstensen and Lou Cornicelli Preston Public Meeting December 18, 2018 Agenda Opening Remarks Brief overview of Chronic Wasting Disease (CWD) 2016-18 surveillance results

567 views • 25 slides
CWD Management Options for Deer, Elk and Moose Herd Health Commonality among all stakeholders

CWD Management Options for Deer, Elk and Moose Herd Health Commonality among all stakeholders

CWD Management Options for Deer, Elk and Moose Herd Health Commonality among all stakeholders Think long-term CWD Management Options for Deer, Elk and Moose Herd Health Commonality among all stakeholders Think long-term

558 views • 11 slides
Conservation Services Programme Observer Report: 1 July 2008 to 30 June 2009 Kris Ramm Marine

Conservation Services Programme Observer Report: 1 July 2008 to 30 June 2009 Kris Ramm Marine

Conservation Services Programme Observer Report: 1 July 2008 to 30 June 2009 Kris Ramm Marine Conservation Services 1 CSP Observer Coverage Achieved versus Planned during 08/09 Total Fishery Planned Achieved % achieved Observer days

983 views • 70 slides

More recommend