Polymorphism Control of a Schiff base via solvent-free and solution - - PowerPoint PPT Presentation
Polymorphism Control of a Schiff base via solvent-free and solution based synthesis Marija Zbanik ab , Ivana Nogalo a and Dominik Cini a Laboratory of General and Inorganic Chemistry, Department of Chemistry, University of Zagreb, Zagreb,
Laboratory of General and Inorganic Chemistry, Department of Chemistry, University of Zagreb, Zagreb, Croatia 10002, E-mail: mzbacnik@chem.pmf.hr.
bDepartment of Chemistry, University of the Free State, Bloemfontein
9300, South Africa, E-mail: ZbacnikM@ufs.ac.za
3
4
5
H2N CH3 O
O H OH O H3C
N H OH CH3 O
H2N CH3 O
6
Crystallization Room temperature 96 % or absolute ethanol Crystallization 8 °C 96 % ethanol; very fast filtration of 3aa 96 % or absolute ethanol; slow filtration of 3aa
7
Crystallization Room temperature absolute ethanol; very fast filtration Crystallization 8 °C absolute ethanol ; very fast filtration of 3aa
8
Crystallization 8 °C 96 % ethanol; very fast filtration
9
Crystallization Room temperature 96 % or absolute ethanol; medium fast filtration
10
11
5 10 15 20 25 30 35 40 45 II – at 25 °C II – heated to 82 °C II – heated to 101°C II – heated to 106 °C II – heated to 116 °C
2θ / ° III – 25 °c
12
13