Open Access to Scientific Data & Publications Malcolm Skingle - - PowerPoint PPT Presentation

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Open Access to Scientific Data & Publications Malcolm Skingle - - PowerPoint PPT Presentation

Open Access to Scientific Data & Publications Malcolm Skingle CBE DSc PhD Director Academic Liaison Westminster Business Forum Drug Discovery 5 th Feb 2013 Royal Society, London GSK currently have no formal Position Statement on


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Open Access to Scientific Data & Publications

Malcolm Skingle CBE DSc PhD

Director – Academic Liaison Drug Discovery

Westminster Business Forum 5th Feb 2013 Royal Society, London

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  • GSK currently have no formal Position

Statement on pre-clinical scientific publication & APCs but support the principle of Open Access to scientific data

  • GSK share data, reagents & resources with

external parties in a bid to expand areas of the science base of value to the whole scientific community

  • The impact factors for GSK published papers

are comparable to those of academia.

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Papers with GSK Author 2000-2012 100+ citations

Where GSK Authors have contributed to a paper that can be found in Scopus with over 100 citations

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Open Innovation - Malaria

  • Attempts to generate leads vs malaria

– GSK screened 2 million compounds vs the malaria parasite P.falciparum to generate 13,500 hits – Took 5 GSK scientists 1 year to complete – GSK to publish the chemical structures & associated assay data – Data freely available via a user-friendly database

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EMBL-EBI Database for Mining Malaria Compound Set - www.ebi.ac.uk/chemblntd

John Overington, EBI

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“Open source” ‐ malaria screening

GSK Malaria Set “TCAMS” MMV Malaria Box (~50% from TCAMS)

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Shared with ~14 groups Shared with ~100 groups

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Thursday 11 October 2012, London UK GSK announces further initiatives to advance

  • penness and collaboration to help tackle

global health challenges

  • Tuberculosis (TB) ‘compound library’ to be

made available to help stimulate research into TB

  • Investment in GSK’s Tres Cantos Open Lab to

be doubled with an additional £5m funding awarded

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Concluding Remarks

  • GSK are changing their internal structures to be

more open & transparent with the external science base.

  • We are keen to share our data with external

scientists in order to expand the science base. Open Access publishing is part of this continuum

  • The more science you share with others, the

more you get back from external sources

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We are looking for innovation wherever it may originate