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O-G CANCER THE NEXT 10 YEARS Oesophageal cancer incidence 1975- - - PowerPoint PPT Presentation
O-G CANCER THE NEXT 10 YEARS Oesophageal cancer incidence 1975- - - PowerPoint PPT Presentation
O-G CANCER THE NEXT 10 YEARS Oesophageal cancer incidence 1975- 2011 The future .. Prevention Risk factors Early detection Public awareness Screening techniques Better access & quality of endoscopy Better
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Oesophageal cancer incidence 1975- 2011
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The future…..
Prevention
Risk factors
Early detection
Public awareness Screening techniques Better access & quality of endoscopy
Better understanding of the biology Better treatmentsn
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Awareness & early diagnosis
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Early detection – the challenge
GP
Disease free No or subtle symptoms Dysphagia, heartburn
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Screening for Barrett’s
Acceptability and accuracy of a non-endoscopic screening test for Barrett's oesophagus in primary care: cohort study.
Kadri SR et al
- BMJ. 2010 Sep 10;341:c4372. doi: 10.1136/bmj.c4372
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Brit J Cancer 2013;108:914-50
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Access & quality of endoscopy
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Cance r Cance r
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Better understanding of the disease
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Gender and oesophageal cancer
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The significance of oestrogen receptors in the biological behaviour of oesophageal cancer
Increase of oestrogen
receptors in
- esophageal cancer
Blocking of
- esophageal
receptors may provide an additional treatment of
- esophageal cancer
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Better treatments
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Better treatments
New drugs
Receptor blockers Immunotherapy
Tailoring treatments to individuals
What combination of chemo, DXT, surgery?
Better selection for surgery Endoscopic treatments for early disease