New Approaches to Managing Airway Disease in Children Anna K. - - PDF document

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New Approaches to Managing Airway Disease in Children Anna K. - - PDF document

New Approaches to Managing Airway Disease in Children Anna K. Meyer, MD, FAAP Assistant Professor Division of Pediatric Otolaryngology University of California, San Francisco February 2013 No disclosures 2 1 Overview


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New Approaches to Managing Airway Disease in Children

Anna K. Meyer, MD, FAAP Assistant Professor Division of Pediatric Otolaryngology University of California, San Francisco

February 2013

  • No disclosures

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Overview

  • Laryngotracheal Stenosis
  • Laryngomalacia
  • Airway Hemangioma
  • Obstructive Sleep Apnea
  • Vocal Cord Paralysis
  • EXIT Procedure*

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*time-permitting

Laryngotracheal Stenosis

  • NICU management: Prevention

– Small ETT – Uncuffed ETT – Reduced Intubation

  • Limitation of meconium ETT suction
  • Reduced oxygen delivery
  • CPAP*
  • Surfactant

– Reducing infection

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Jatana, et al., 2010

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Laryngotracheal Stenosis

  • Balloon dilation
  • Advantage over rigid or bougie dilation

– Maximize radial direction – Less shearing vertical damage to airway

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Choanal Atresia

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Laryngotracheal Stenosis

  • Endoscopic posterior graft
  • Gerber, et al., 2013: 89% success

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Laryngomalacia

  • All that wheezes is not asthma…..

……all noisy breathing is not laryngomalacia.

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Stridor: Evaluation

  • SPECSR

– Severity – Progression/ Phase – Eating – Cyanosis/ apneas – Sleeping – Radiologic review

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Etiologies of Stridor

  • Supralaryngeal

– Pyriform aperture stenosis – Choanal atresia – Lacrimal duct cyst – Nasopharyngeal mass – Facial skeletal abnormalities – Base of tongue mass – Adenotonsillar hypertrophy – macroglossia

  • Laryngeal

– Laryngomalacia – Vocal cord paralysis – Saccular cysts – Webs – Respiratory papillomas – Subglottic hemangiomas – Subglottic stenosis – Laryngeal cleft – Foreign body

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Etiologies of Stridor

 Tracheobronchial – Tracheomalacia, bronchomalacia – Vascular anomalies – Stenosis – Foreign body – TEF – Bronchiolitis, bronchitis

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Evaluation

Flexible laryngoscopy

High kilovoltage, magnified airway films

Airway fluoroscopy

Swallow studies

Rigid endoscopy – which patients? Classic Laryngomalacia Inspiratory-only Stridor No work of breathing Normal weight gain No OSA Normal AP films Re-evaluation in one month

Mancuso, et al., 1996

Inconsistent with Laryngomalacia Expiratory or biphasic stridor Work of breathing Poor weight gain Abnormal AP films Supraglottoplasty Rigid endoscopy

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Medical Management

  • Reassuring parents of favorable prognosis

– Condition is usually self-limiting

  • Position adjustments

– More prominent when supine or agitated

  • Reflux precautions/ medications
  • Frequent evaluation by pediatrician to

assess: – Growth – Feeding – Breathing

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Surgical Indications

  • Failure to thrive
  • Obstructive sleep apnea
  • Awake persistent apneas/ cyanosis
  • Pulmonary hypertension/ Cor pulmonale
  • Severe reflux
  • Recurrent aspiration
  • Disease not spontaneously resolve
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Treatment

  • Approaches
  • Laser
  • Microdebrider
  • Cold steel
  • Unilateral vs. bilateral

Airway Hemangioma

  • Beta Blockers

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9 weeks old Post-4 weeks of systemic corticosteroids

Léauté-Labrèze C et al June 12, 2008

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10 weeks old post-7 days propranolol

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6 months age steroids discontinued at 2 mos

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9 mos age propranolol discontinued

Airway Hemangioma

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At admission 6 days post-propranolol

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Airway Hemangioma

  • 5-10% non-responders
  • Traditional approaches: laser, steroids, etc.
  • Submucous resection

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Vijayasekaran, et al., 2006; O- Lee & Messner, 2008

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Obstructive Sleep Apnea

  • Failure of tonsillectomy

– SDB often is multifactorial – Effective in 60-70% of children with significant tonsillar hypertrophy – Only effective in 10 – 25% of complex children

  • Obesity
  • Retrognathia
  • Craniofacial syndromes
  • Neuromuscular disorders
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Common Causes of Residual OSA in Children

  • Adenoid pad regrowth
  • Lingual tonsillar hypertrophy
  • Tongue base collapse
  • Occult laryngomalacia
  • Inferior turbinate hypertrophy

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Sleep Endoscopy

Durr, Meyer, Rosbe, 2012; Koltai, 2012

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Treatments Tongue Base

  • Tongue reduction
  • Suture suspension
  • Anterior mandibular
  • steotomy/genioglo

ssus advancement

  • Mandibular

distraction

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Vocal cord paralysis

  • Acute paralysis

– Tracheotomy – Vocal cord suture lateralization – Injection vocal cord augmentation

  • Long-term/permanent paralysis

– Endoscopic posterior graft – Arytenoidectomy – Cordotomy – Thyroplasty – Reinnervation

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Chen & Inglis, 2011

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Reversible lateralization

  • Lichtenberger, 1983
  • Endo-extralaryngeal carrier instrument
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Suture Lateralization

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Pediatric Lateralization

Matthur, et al., 2004

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EXIT Procedure

  • EX utero Intrapartum Treatment
  • Defined by interdisciplinary approach

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Cervical Masses

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Congenital High Airway Obstruction Syndrome (CHAOS)

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Summary

  • More endoscopic approaches
  • More technology
  • Earlier interventions
  • More complex evaluations

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