Multidisciplinary approaches applied to cope with Zika epidemics - - PowerPoint PPT Presentation

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Multidisciplinary approaches applied to cope with Zika epidemics - - PowerPoint PPT Presentation

MEETING OF THE INSTITUT PASTEUR INTERNATIONAL NETWORK (RIIP) AMERICAN REGION Multidisciplinary approaches applied to cope with Zika epidemics Sinval Brando Filho, PhD Celina Turchi Martelli, PhD UFPE Celina Laura Thalia Ricardo


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MEETING OF THE INSTITUT PASTEUR INTERNATIONAL NETWORK (RIIP) – AMERICAN REGION

Multidisciplinary approaches applied to cope with Zika epidemics

Sinval Brandão Filho, PhD Celina Turchi Martelli, PhD

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UFPE

www.cpqam.fiocruz.br/merg/

Ricardo Ximenes Laura Rodrigues Celina Turchi Thalia Araujo Wayner Souza Fátima Militão Ernesto Marques Marli Tenório Enrique Vazquez Cynthia Braga Rafael Dhalia Sinval Brandão

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2014

  • French Polynesia - 42 cases of GBS during Zika virus outbreak
  • After Brazil alert - increase in congenital abnormalities noticed

2015

  • Zika cases in Northeast Brazil
  • September –October Cluster of microcephaly
  • November 11, Brazilian MoH declares Public Health Emergency

2016

  • February 1, WHO declares PHEIC*
  • Recommends increased research

* Public Health Emergency of International Concern

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Public Health Emergency of International Concern

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2015

11th Nov Declaration of National Public Health Emergency 1st Feb PHEIC WHO October MERG Aug – Sep State Health Department, MoH Brazil

2016

Microcephaly in Brazil

2017

11th Mar PHEIC WHO

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Cases series studies

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DOI 10.1002/ajmg.a.38170

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Descriptive studies

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Case-control study

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Challenges in Arboviroses Laboratory

Laboratory of Vaccinology and Experimental Therapeutics

  • Isolation of ZIKV: patient with GBS, Recife 2015
  • Detection of Positive IgM for Zika virus in the cerebrospinal fluid of 30

neonates with microcephaly in Brazil. Cordeiro,et al The Lancet 387, 2016.

  • Reference laboratory for ZIKV
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Capacity building & Communication

Fiocruz- Pernambuco March 1rst, 2016

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Fiocruz- PE, March 12, 2019

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Research Collaboration

ZikaPlan Kick-off meeting in Recife, October 2016

RENEZIKA: Rede Nacional de Especialistas em Zika Brazilian Ministry of Health

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ZIKAV scientific publications indexed in international databases (2007–2017)

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Global network of ZIKAV research Latin American Countries -based authors

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Zika virus infection as a public health threat

  • Are we prepared for the next Zika outbreak?
  • How to improve the clinical and laboratory diagnosis of vector-

borne infections?

  • What are the implications of the Zika current epidemiology for

vaccine development and its future implementation?

  • Are the ongoing Zika consortiums sustainable networks in the

following years?

  • How to provide sustainable health care for the affected children

and their families?

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Source: Blog NE10. Disponível em: https://blogs.ne10.uol.com.br/social1/2019/03/14/premio-tacaruna-mulher/ Acesso em 18 de Março de 2019.

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“Every virus tells a story. We still don’t know how this one ends. Only that we’re the ones that will write it”