Multidisciplinary approaches applied to cope with Zika epidemics - PowerPoint PPT Presentation

MEETING OF THE INSTITUT PASTEUR INTERNATIONAL NETWORK (RIIP) – AMERICAN REGION Multidisciplinary approaches applied to cope with Zika epidemics Sinval Brandão Filho, PhD Celina Turchi Martelli, PhD

UFPE Celina Laura Thalia Ricardo Turchi Rodrigues Ximenes Araujo Ernesto Fátima Marli Wayner Marques Militão Tenório Souza www.cpqam.fiocruz.br/merg/ Cynthia Enrique Rafael Sinval Braga Vazquez Dhalia Brandão

• French Polynesia - 42 cases of GBS during Zika virus outbreak • After Brazil alert - increase in congenital abnormalities noticed 2014 • Zika cases in Northeast Brazil • September – October Cluster of microcephaly 2015 • November 11, Brazilian MoH declares Public Health Emergency • February 1, WHO declares PHEIC* 2016 • Recommends increased research * Public Health Emergency of International Concern

Public Health Emergency of International Concern

Microcephaly in Brazil 11 th Nov 1 st Feb Declaration of October National Public 11th Mar PHEIC Health Aug – Sep WHO MERG Emergency PHEIC State Health WHO Department, MoH Brazil 2016 2017 2015

Cases series studies

DOI 10.1002/ajmg.a.38170

Descriptive studies

Case-control study

Challenges in Arboviroses Laboratory Laboratory of Vaccinology and Experimental Therapeutics  Isolation of ZIKV: patient with GBS, Recife 2015  Detection of Positive IgM for Zika virus in the cerebrospinal fluid of 30 neonates with microcephaly in Brazil. Cordeiro,et al The Lancet 387, 2016.  Reference laboratory for ZIKV

Capacity building & Communication Fiocruz- Pernambuco March 1rst, 2016

Fiocruz- PE, March 12, 2019

Research Collaboration RENEZIKA: Rede Nacional de Especialistas em Zika Brazilian Ministry of Health ZikaPlan Kick-off meeting in Recife, October 2016

ZIKAV scientific publications indexed in international databases (2007 – 2017)

Global network of ZIKAV research Latin American Countries -based authors

Zika virus infection as a public health threat • Are we prepared for the next Zika outbreak? • How to improve the clinical and laboratory diagnosis of vector- borne infections? • What are the implications of the Zika current epidemiology for vaccine development and its future implementation? • Are the ongoing Zika consortiums sustainable networks in the following years? • How to provide sustainable health care for the affected children and their families?

Source: Blog NE10. Disponível em: https://blogs.ne10.uol.com.br/social1/2019/03/14/premio-tacaruna-mulher/ Acesso em 18 de Março de 2019.

“Every virus tells a story. We still don’t know how this one ends. Only that we’re the ones that will write it”