Microdosimetric GEANT4 and FLUKA Monte- - Microdosimetric GEANT4 - - PowerPoint PPT Presentation

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health physics health pyhsics division division risk and safety Microdosimetric GEANT4 and FLUKA Monte- - Microdosimetric GEANT4 and FLUKA Monte Carlo Simulations and Measurements of Heavy Carlo Simulations and Measurements of Heavy Ion

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SLIDE 1

peter.beck@arcs.ac.at health physics division health pyhsics division risk and safety

Microdosimetric GEANT4 and FLUKA Monte Microdosimetric GEANT4 and FLUKA Monte-

  • Carlo Simulations and Measurements of Heavy

Carlo Simulations and Measurements of Heavy Ion Irradiation of Silicon and Tissue Ion Irradiation of Silicon and Tissue

  • P. Beck
  • P. Beck1

1, M. Wind

, M. Wind1,2

1,2, S. Rollet

, S. Rollet1

1, M. Latocha

, M. Latocha1,3

1,3,

, F.Bock F.Bock1,2

1,2, H. B

, H. Bö öck ck2

2, Y. Uchihori

, Y. Uchihori5

5

1ARC Seibersdorf research, Health Physics Division, 2444 Seibersdorf, Austria 2Vienna University of Technology, Atomic Institute, 1020 Vienna, Austria 3Institute of Nuclear Physics, Polish Academy of Sciences, 31-342 Kraków, Poland 4National Institute of Radiological Sciences, (NIRS), Inage, Chiba, JAPAN

Acknowledgment: Support by ARCS (NANODOS project), NIRS, and ICCHIBAN working group.

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SLIDE 2

peter.beck@arcs.ac.at

Outline Outline

  • Simulation

Simulation of radiation effects

  • f radiation effects
  • Code validation by using

Code validation by using microdosimetric microdosimetric quantities quantities

  • Comparison of

Comparison of measurements measurements and and simulations simulations

– –

heavy ion heavy ion irradiation (silicon & tissue) irradiation (silicon & tissue)

– –

microdosimetric measurements ( microdosimetric measurements (2 2µ µm m sensitive volume) sensitive volume)

– –

Monte Carlo simulation ( Monte Carlo simulation (FLUKA FLUKA, , GEANT4 GEANT4) )

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SLIDE 3

peter.beck@arcs.ac.at

Why Radiation Simulation? Why Radiation Simulation?

Simulation Simulation supports supports… …

  • understanding radiation

understanding radiation interaction mechanism interaction mechanism

  • irradiation test

irradiation test measurements measurements

  • design

design radiation hard semiconductor radiation hard semiconductor

  • optimize
  • ptimize shielding

shielding

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SLIDE 4

peter.beck@arcs.ac.at

Validation Approach Validation Approach

  • Validation

Validation of Monte Carlo high energy particle transport

  • f Monte Carlo high energy particle transport
  • Using

Using microdosimetric microdosimetric methods methods

  • Compare

Compare measurements measurements with with simulations simulations

– –

absorbed dose absorbed dose

– –

lineal energy spectra lineal energy spectra

– –

dose mean lineal energy dose mean lineal energy

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SLIDE 5

peter.beck@arcs.ac.at

Monte Carlo Simulation with FLUKA & GEANT4 Monte Carlo Simulation with FLUKA & GEANT4

  • Transport

Transport of

  • f

– –

electromagnetic particles electromagnetic particles

– –

hadronic particles hadronic particles

– –

heavy ions heavy ions

  • Energy

Energy: 20 : 20 TeV TeV to to … …

– –

10keV (all particles) 10keV (all particles)

– –

thermal neutrons (~ 0,1 thermal neutrons (~ 0,1 eV eV) )

– –

1 1 keV keV (ph, e (ph, e-

  • ) / FLUKA

) / FLUKA

– –

250eV (ph, e) / GEANT4 250eV (ph, e) / GEANT4

  • Score

Score energy deposition energy deposition

– –

event by event event by event

  • Simulation of

Simulation of microdosimetric microdosimetric spectra

http://www.fluka.org/index.html

spectra

http://geant4.web.cern.ch/geant4/

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SLIDE 6

peter.beck@arcs.ac.at

Dosimetry Dosimetry -

  • Microdosimetry

Microdosimetry

cm ~ mm Absorbed dose: [D] = Gy = J · kg-1 µm ~ nm Lineal energy: [ y ] = keV · µm-1 LET = MeV·cm2·mg-1

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SLIDE 7

peter.beck@arcs.ac.at

Micro Micro-

  • Dosimeter (Rossi

Dosimeter (Rossi-

  • Type)

Type)

Source: Columbia University

  • TEPC (

TEPC (tissue equivalent proportional counter tissue equivalent proportional counter) )

  • SEPC (

SEPC (silicon equivalent proportional counter silicon equivalent proportional counter) ) Electronics

Tissue / Silicon Equivalent Chamber (10 µm ~ 100nm)

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SLIDE 8

peter.beck@arcs.ac.at

HIMAC HIMAC -

  • Heavy Ion Medical Accelerator, Chiba, Japan

Heavy Ion Medical Accelerator, Chiba, Japan

  • HIMAC

HIMAC

– –

is used for is used for cancer therapy cancer therapy

– –

is available for is available for scientific experiments scientific experiments during night during night time and weekends time and weekends

  • ICCHIBAN

ICCHIBAN -

  • 8

8

– –

Measurements in the framework of Measurements in the framework of Inter Inter Comparison for Cosmic Comparison for Cosmic-

  • ray with Heavy Ion

ray with Heavy Ion Beams at Beams at NIRS NIRS

– –

Radiation study at the Radiation study at the International Space Station International Space Station

  • Tissue & Silicon irradiation measurements

Tissue & Silicon irradiation measurements

– –

O 400 O 400 MeV/u MeV/u

– –

Fe 300 Fe 300 MeV/u MeV/u

HIMAC

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SLIDE 9

peter.beck@arcs.ac.at

High Energy Particle Transport Simulation High Energy Particle Transport Simulation

  • Detector

Detector geometry geometry and and material material

  • Source:

Source: heavy ions heavy ions

– –

O 400 O 400 MeV/u MeV/u

– –

Fe 300 Fe 300 MeV/u MeV/u

  • Analysis of

Analysis of beam characteristics beam characteristics (shape, divergence, etc.) (shape, divergence, etc.)

  • High energy particle

High energy particle Monte Carlo Monte Carlo transport codes transport codes

– –

FLUKA FLUKA-

  • 2005

2005

– –

GEANT4 GEANT4

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SLIDE 10

peter.beck@arcs.ac.at

Simulation Results: Particle fluence density Simulation Results: Particle fluence density

(particle (particle · ·cm cm-

  • ³

³ per unit source) per unit source) Oxygen 400 MeV/u broad beam

  • Neutron fluence rate
  • Inside tissue

Iron 300 MeV/u small beam

  • Neutron fluence rate
  • Inside tissue
  • Electron fluence rate
  • Inside silicon
  • Electron fluence rate
  • Inside silicon
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SLIDE 11

peter.beck@arcs.ac.at

Total absorbed dose in 2 Total absorbed dose in 2µ µm sensitive silicon & tissue m sensitive silicon & tissue volume due to heavy ion irradiation volume due to heavy ion irradiation

Instrument Beam Measurement FLUKA Geant 4 MeV/u (Gy / source particle × 10-10) TEPC O 400 2.3 ± 0.3 2.9 ± 0.3 2.7 ± 0.3 Fe 300 47.0 ± 7.0 45.8 ± 4.6 43.3 ± 4.3 SEPC O 400 2.1± 0.3 2.8 ± 0.3 2.7 ± 0.3 Fe 300 44.4 ± 6.7 45.8 ± 4.6 42.3 ± 4.2

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SLIDE 12

peter.beck@arcs.ac.at

Microdosimetric absorbed dose spectra in Microdosimetric absorbed dose spectra in tissue tissue Measurements, FLUKA, GEANT4 Measurements, FLUKA, GEANT4

Oxygen 400 MeV/u irradiation Iron 300 MeV/u irradiation

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SLIDE 13

peter.beck@arcs.ac.at

Microdosimetric absorbed dose spectra in Microdosimetric absorbed dose spectra in silicon silicon Measurements, FLUKA, GEANT4 Measurements, FLUKA, GEANT4

Oxygen 400 MeV/u irradiation Iron 300 MeV/u irradiation

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SLIDE 14

peter.beck@arcs.ac.at

D

y

Ratios of Dose Mean Lineal Energy Ratios of Dose Mean Lineal Energy

Instrument Beam (MeV/u) FLUKA/Meas. Geant 4/Meas. TEPC O 400 1.04 ± 0.16 0.97 ± 0.15 Fe 300 1.05 ± 0.16 1.00 ± 0.15 SEPC O 400 0.89 ± 0.13 1.22± 0.18 Fe 300 1.01 ± 0.15 0.93± 0.14

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SLIDE 15

peter.beck@arcs.ac.at

Ratios of dose mean lineal energy Ratios of dose mean lineal energy

D

y

0,6 0,7 0,8 0,9 1,0 1,1 1,2 1,3 1,4 1,5 1,6

tissue (O 400 MeV/u) silicon (O 400 MeV/u) tissue (Fe 300 MeV/u) silicon (Fe 300 MeV/u) Ratio: calculation / measurement FLUKA/Measurement Geant4/Measurement

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SLIDE 16

peter.beck@arcs.ac.at

Conclusions Conclusions

  • Successful modelling

Successful modelling of heavy ion irradiation experiments with

  • f heavy ion irradiation experiments with

– –

FLUKA FLUKA

– –

GEANT4 GEANT4

  • Successful simulation of

Successful simulation of 2 2µ µm sizes m sizes silicon silicon & & tissue tissue

  • Ration of

Ration of calculated calculated and and measured measured total total absorbed dose absorbed dose between between 1.3 1.3 and and 0.92 0.92 (mean over all measurements (mean over all measurements 1.1 1.1). ).

  • Agreement calculated and measured

Agreement calculated and measured dose mean lineal energy dose mean lineal energy within within 10%. 10%.

  • FLUKA

FLUKA and and GEANT4 GEANT4 calculations agree within calculations agree within 5 5-

  • 10%

10%