Leptospirosis in the Philippines Jun unFu Fuji jii, M.D.,Ph.D. - - PowerPoint PPT Presentation

Advocacy Activities for the Control and Prevention of Leptospirosis in the Philippines

Jun unFu Fuji jii, M.D.,Ph.D. D.

Associate Professor Department of Bacteriology Graduate school of Medical Sciences Kyushu University

• Leptospirosis is a bacterial disease that affects humans and

animals.

• It is caused by bacteria of the genus Leptospira.
• If not treated, the patient could develop kidney damage,

meningitis, liver failure, and respiratory distress or death.

What is leptospirosis?

Symptoms:

• high fever
• severe headache
• muscle pains
• vomiting
• jaundice (yellow skin and eyes)
• red eyes

• Dr. Adolf Weil described leptospirosis as a disease entity in
• 1886. His name is still attached to a serious form of

leptospirosis called Weil's disease. Leptospires were recognized by Dr.Ryokichi Inada in Kyushu University in Japan.

History of leptospirosis

• Dr. Inada

 Dr. Inada and colleagues

• f Kyushu University

reported Leptospira as the causative agent of leptospirosis.  He is the first professor

• f department of first

internal medicine.  The centennial of the leptosires discovery is scheduled in 2013 in Kyushu University

1915: discovery of leptospires

Prevalence of Leptospirosis

Humans become infected through contact with water, or soil contaminated with urine

• f infected animals like rodents (rats and

mice).

How do people get leptospirosis?

flood in Philippines

Estimated number of annual cases: 350,000 to 500,000, 5,779 deaths in 10 years (1999 World Health Organization & International Leptospirosis Society survey)

Epidemiology in Philippines

Leptospirosis outbreak after Typhoon ‘Ondoy’ reported on Nov 6, 2009:

• 3, 125 cases from National Capital

Region (NCR), Regions I, II, III, IV-A and Cordillera Autonomous Region (CAR)

• 240 mortality

(Case Fatality Rate= 7.6%)

LEPCON project has started this year

Collaborative Framework for the Control and Prevention of Leptospirosis in the Philippines

UP Mindanao Davao Medical Center UP Visayas West Visayas Medical Center

UP Manila CPH Kyushu U, Chiba U

With Support from DOST, WHO, JICA, JST

Department of Health ~400 Sentinel Sites Philippine Carabao Center Other Referring Hospitals & health care institutions

Purpose of LEPCON

Research and development (R&D) capacity of College of Public Health (CPH-UPM) is enhanced for prevention and control of leptospirosis through the collaborative research

Project Leader: Professor Shin-ichi Yoshida, Department of Bacteriology, Graduate School of Medical Sciences, Kyushu University

Output of the LEPCON

Advocacy Burden of Disease by Bacteriological study Center for LEPCON Development of Diagnostic kits and DNA vaccines Epidemiology and Economic burden

• 0. Laboratory Renovation
• 1. Epidemiology

1) Bacteriological surveillance 2) Burden of disease 3) Environmental risk factors

• 2. Diagnostic kit
• 3. DNA vaccine
• 4. Advocacy

Group A: Microbiology 1)Bacterial surveillance 2) Diagnostic kit 3) DNA vaccine Group C: Environmental risk factors Group D: Advocacy Fujii/ Guevarra

Plan of Operation/Project Design Matrix and Working group in Japan and Philippines

Group B: Burden of disease

Advocacy Activity

• To confirm the target hospitals and health centers.
• To collect data on the knowledge on leptospirosis from

clinicians, nurses, and other health workers.

• To develop materials such as handbook or leaflets on

leptospirosis for clinicians, nurses, and other health workers.

• To capacitate the clinicians, nurses, and other health workers,

and distribute materials.

• To disseminate knowledge on leptospirosis to the public.
• To conduct evaluation of advocacy activities.
• To organize scientific meetings, workshops or fora to present

the progress and results of the project and for advocacy to policy makers for future leptospirosis control

How do we use the Asia-Pacific Advanced Network?

• Real-time conference on leptospirosis among collaborating

institutes for the advocacy activity.

• Exchange of information regarding laboratory high technologies

such as microarray, proteomics and vaccine development in Kyushu University.

• Medical education including diagnosis and therapeutic methods
• f leptospirosis to the doctor and nurse in Japan and Philippines
• Finally, we ask to connect Asia-Pacific Advanced Network

between Faculty of Medical Sciences Building B Basic Sciences, Kyushu University and Lara Hall, College of Public Health, University of the Philippines Manila by APAN engineers.

Faculty of Medical Sciences Building B Basic Sciences Kyushu University

Lara Hall, College of Public Health, University of the Philippines Manila

Upgrading of Leptospirosis Laboratory through JICA Grant

Upgrading of Leptospirosis Laboratory through JICA Grant