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Interim Results Presentation For the six months ended 31 December 2017 TABLE OF CONTENTS TA Stephen Saad Group Chief Executive Aspens 20 Year History Unpacking Aspen H1 2018 Performance Review Gus Attridge Deputy Group Chief Executive


  1. Interim Results Presentation For the six months ended 31 December 2017

  2. TABLE OF CONTENTS TA Stephen Saad Group Chief Executive Aspen’s 20 Year History Unpacking Aspen H1 2018 Performance Review Gus Attridge Deputy Group Chief Executive Financial Review Stephen Saad Summary & Prospects Appendices

  3. FINANCIAL HIGHLIGHTS 3 Strong H1 performance � Re Revenue at ZAR 21.9bn − Revenue momentum sustained from H2 2017 � EB EBITDA at at ZAR 6.3bn − EBITDA growth above revenue growth − Operating profit to cash flow conversion rate 78% 78% � Forecast at 100% for the year CE CER Growth Gr Growth vs vs prior year � NH NHEPS (c (cents) 26 26% 25 25% 871.9 H1 2018 27 27% 37 37% H2 2017 771.2

  4. GROUP REVENUE 4 R’million H1 2018 H1 2017 % change H1 2017 (CER)* % change Commercial Pharma Co 17 17 121 121 14 14 997 997 14% 14% 14 893 14 893 15% 15% Anaesthetics 4 409 2 817 57% 2 766 59% Thrombosis 3 276 2 729 20% 2 793 17% High Potency & Cytotoxics 2 193 2 417 -9% 2 383 -8% Regional Brands 7 243 7 035 3% 6 951 4% Nu Nutritionals 1 610 1 610 1 633 1 633 -1% 1% 1 1 622 622 -1% 1% Ma Manuf nufactur uring ing 3 3 193 193 3 3 192 192 0% 0% 3 3 236 236 -1% 1% To Total Revenue 21 21 924 924 19 19 822 822 11% 11% 19 751 19 751 11% 11% *CER reflects the underlying operational performance - H1 2017 restated at H1 2018 average exchange rates

  5. Aspen’s 20-year history

  6. CELEBRATING 20 YEARS | 1999 - 2018 6 FY FY1999 – FY FY2013 FY FY2014 – H1 H1 2018 2018 (annualis lised) From humble beginnings to regional leadership From regional leadership to global therapeutic leadership annualised Going for 20th year of unbroken NHEPS growth

  7. FY 1999 – FY 2013 7 FY 2013 Sales: ZAR 19.3bn FY 1999 Sales: ZAR 0.5bn SA & Australia = 73% Rest of • World No 1 in SA ~ 1 in 4 scripts South Africa 27% dispensed 36% • No 1 in Australia ~ 1 in 5 scripts written Australasia 37% South Africa only From humble beginnings in Durban to regional leadership

  8. REGIONAL LEARNING DEFINES GLOBAL STRATEGY 8 � St � Re Strategic review of of ou our strengths & weaknesses in 2013 Returns from scale, sales and supply chain − Risk of commoditisation of generics − Critical mass gives returns − Funding required for patents − Global strategy formulated − Fifteen years taken to build leading regional presence − Focus shift from regional leadership � More than a lifetime needed to establish global − Targeted global leadership in specialist therapeutic presence categories � Cr � Sp Critical suc uccess factors Specialty – id ideal fit it − Quality − Sustainable cash flows − Affordability − Continued growth through investment in brands and supply chain − Integrity − Increased barriers to entry � Partner of choice − Representation Regional Leadership to Global Therapeutic Leadership

  9. FY 2013 – H1 2018 (ANNUALISED) 9 FY 2013 Sales: ZAR 19.3bn H1 2018 (annualised) Sales : ZAR 43.8bn SA & Australia = 73% SA & Australia = 35%* South Africa • No.1 in Anaesthetics globally (ex-USA) Rest of 20% World South Africa • No.2 in injectable Anticoagulants 27% 36% globally (ex-USA) Australasia Rest of World • High Potency capability 15% Australasia 65% - leading global producer of 37% • Acquisitive period regulated hormonal products • Geographic diversity • SA’s most global company - 25 manufacturing facilities worldwide - Over 10 000 employees in ~ 50 countries * Reduced by divestment of commodity products Revenue has more than doubled | but at what cos ost?

  10. Unpacking Aspen FY 2013 – H1 2018

  11. DEBT & ASSETS 11 � Deb Debt − Net borrowings ↑ ZAR 32.0bn since FY 2013 67.3 � As Assets − Significant increase in balance sheet values � Intangibles ↑ ZAR 48.4bn 43.1 � PPE ↑ ZAR 5.8bn � Applied to Working Capital ↑ ZAR 12.4bn 18.9 17.8 11.1 5.4 FY 2013 H1 2018 Net borrowings (ZAR'bn) Intangible Assets (ZAR'bn) Working Capital (ZAR'bn)

  12. INTANGIBLE ASSETS & GOODWILL 12 Hi High Potency & & Regional Brands Re Th Therapeutic class Ana Anaesthetics Th Thrombosis Other Ot Cytotoxic Cyt So South Africa Aus Australia Sales Multiple 2. 2.6 2. 2.1 2. 2.8 0. 0.4 1.9 1. 0.9 0. 23.0 14.6 14.0 13.0 12.1 8.8 6.9 6.6 5.8 4.4 3.6 2.1 Anaesthetics Thrombosis High Potency and South Africa - Australia - Domestic Other Cytotoxics Domestic H1 2018 Revenue (annualised) (ZAR'bn) H1 2018 Book Value* (ZAR'bn) � Intangibles - life blood of our business *Intangible assets (excluding Development Costs and Computer software) plus Goodwill − 1.6x H1 2018 sales (annualised) � You could pay a multiple of ±1.6x for a brand forecast to decline in double digits � You could pay ±6/7x sales for a brand forecast to increase at 5% into perpetuity Our intangible assets are worth significantly more than their book value

  13. AMORTISATION OF INTANGIBLES 13 � Am � Us Amortisation treatment differs between generics, Useful life assessed against, inter alia pa patents and nd br brands − Historic & budgeted sales − Aspen has mainly indefinite life intangibles − Investment plans & willingness to commit resources � Means the values are tested annually − Stability of industry & economy � Does not mean infinite life − Redundancy of similar medicines due to changes in market Growth of Top 10 SA products in 2003 preference � Mo Moot point for investors − International peers show GAAP earnings and non-GAAP earnings � Latter has add-back of amortisation 2003 2008 2013 2017 � Benchmark used by global analysts for valuations � Am Amortisation is a ratchet � NO EFFECT ON CASH FLOW − No increases in IP − Only write-downs If we wrote intangibles up to fair value | wou ould you include the write up in earnings?

  14. INVESTMENT IN CAPEX & WORKING CAPITAL 14 � Ca Capex investments critical − Security of supply − Global advantage � Economies of scale � Lower COGS, higher quality � Sustainability of entire business model � Capex projects are long term � All capex approved with a commercial return � Wo Working Capital +ZAR 12.4bn since FY 2013 − Impacted by acquisitions � Increased working capital - a reality for a global business � Manufacturing time of some API exceeds 12 months � Now stabilised All funded without issuing equity

  15. QUALITY OF EARNINGS 15 � We validate quality of earnings by comparing Operating cash flow per share vs Op Op Operating income per share � We have a successful 20 year history on this metric � Cash is King − Cuts through all accounting nuances � Cash then applied to − Capex, acquisitions & dividends � We have funded all acquisitions since 2009 with debt and operating cash flows − Confidence in cash generation − Ability to extract synergies and grow assets organically − We respect our equity � Valuable − Interest well covered � 7.9 times (in terms of Facilities agreement covenant measure) � 8.0 times (EBITDA / Net interest paid)

  16. OUR CURRENT GPS 16 � Aspen has globalised � Leading global and regional positions � Substantial acquisitions have been settled − No 1 in anaesthetics (excluding USA) � Enhanced capability and capacity − No 2 in injectable anticoagulants (excluding USA) − Globally valuable IP − Leading global producer of regulated hormonal products − Differentiated and complex areas − South Africa: ~ 1 in 5 scripts dispensed � e.g. biochemical, steriles and peptides � Geographical diversification − Australia: ~ 1 in 6 scripts written � Only pharma multinational with major weighting towards emerging markets vs developed markets − Supports our volume based model − Attractive partner for developed market focus multinationals � Broader opportunities presented by exciting pipeline

  17. OUR CURRENT GPS (CONTINUED) 17 � Ov � Ac Over the last 12 months Acquisitions in pharma are expensive − ↑ Margins − Acquisitive only financiers in pharma and other industries have often failed − ↑ EBITDA > ↑ Sales � In spite of heavy equity funding � Ac Accelerating EBITDA margin � As Aspen has also grown inorganically − Demonstrates synergy extraction − However we have used cash to finance transactions − Demonstrates contribution from economies of scale of � Supported by organic growth sales growth − Recent results and past performance, clear demonstration − Demonstrates ability to extract organic growth of value extraction We are not financiers running a business | We We are industrialists

  18. WHAT IS THE BOTTOM LINE? | FY 2013 – H1 2018 (ANNUALISED) 18 � Aspen has not only diversified into a global multinational − More than doubled revenue − Without diluting EBITDA margins � Extent of the successful metamorphosis is best measured by Operating profit Op +10 105% NHEPS NHE +10 108% New shares Ne es issued NI NIL This is why we value our equity!

  19. H1 2018 Performance Review

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