SLIDE 1 Scientific Platform Pasteur USP
InovaUSP
- Av. Prof. Lucio Martins Rodrigues 370
Bloco A, Cidade Universitaria CEP 05508-020 São Paulo Brazil
Executive Coordinators :
Luis Carlos S. Ferreira – USP Paola Minoprio – Institut Pasteur
Inauguration the 4th July 2019
SLIDE 2
- Signature on July 1st, 2017, of the USP/PASTEUR/FUSP agreement on the Scientific Platform
Pasteur-USP (SPPU) ,the 1st site of the future IPB, in the state of São Paulo (1700 m2)
- Signature on April 3rd, 2017 of the creation of an Administrative Office of the
Institut Pasteur, USP, São Paulo
SLIDE 3 Global Biodiversity hot spot Climate changes Microbiota
- The 6 Brazilian ecosystems, climate and humidity can
create relevant conditions for the proliferation of vectors
Impact on : migration of vectors, microbial resistance emerging or reemerging diseases transmission anthropological issues, land use, nutrition, water quality
- Agreement on August 31st, 2016 about the Scientific Strategy,
« Microbes, Environment and Health »
- Capitalizing ressources offered in the country and in the South American region contributing to the better
appreciation of the genetic background, environment and microbiome in shaping host immune responses
SLIDE 4 Most specific Initiatives
- Laboratory infrastructures, following strict biosafety and quality issues
- Joint research programs & laboratories and mixed international units
- Trilateral and multilateral innovative courses
- Promotion of innovation leading to discovery of new products and
processes in partnership with public and private industrial sectors
SLIDE 5
Laboratory Title Principal Investigators
Neurological Disease Modeling Patricia Beltrão-Braga Computational Systems Biology Helder Nakaya Systems Virology Paolo Zanotto & Edison L. Durigon Tropical Epidemiology (office) Eduardo Massad Trypanosomatids Infectious Processes Paola Minoprio Biosafety management Pedro Teixeira 1st G4 Jean Pierre Schatzmann Peron Technician (Washing/Kitchen/Medium) To be recruited Technician (Animal House) To be recruited
« Resident scientists »
SLIDE 6
Management of Biosecurity
Establish standardization of procedures in terms of hygiene and safety of laboratories, To translate and adapt French rules to the Brazilian reality Prepare a series of courses that are mandatory for professionals before the platform installations. Pedro Teixeira (FIOCRUZ)
SLIDE 7
System Virology
Applied virology focusing on reverse genetics and viral erotics with viral isolates from relevant outbreaks and with emphasis on emerging viruses. Studies in 2-D and 3-D systems and in vivo studies in murine isolates of YFV, Dengue, CHIKV, USUV, WNV and ZIKV and other pathogenic viruses detected with an emphasis on neuroinvasiveness, neuropathogenesis and blood-brain barrier permeability. Discovery of new viruses, biobanks, immunotherapeutic and diagnostic strategies Edison Durigon & Paolo Zanotto
SLIDE 8
Tropical Epidemiology
Eduardo Massad Development of Mathematical, Computational and Statistical Models of Transmission Dynamics and Control of Tropical Pathogens
SLIDE 9 Neurological Disease Modeling
Patricia C. B. Beltrao Braga
2D 3D
Brain Organoid
SLIDE 10
Neuroimmunology of Arboviruses (G4)
Study of neuroimmune mechanisms involved in nervous system damage caused by arbovirus’ infections in experimental models
Jean Pierre Schatzmann Peron
SLIDE 11 Trypanosomatids Infectious Processes
- 2D and 3D image strategies applied to experimental
models
- New therapeutic and diagnostic strategies
Paola Minoprio
SLIDE 12
Computational Systems Biology
Helder Nakaya.
SLIDE 13 Attract resources from private initiative and the international research funding circuit
13 | Minoprio | 28/06/2019
The ability to innovate is critical for economic, social and environmental development
