IN THE NAME OF GOD PERSISTENCE AND CLEARANCE COVID19 By Dr - - PowerPoint PPT Presentation

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IN THE NAME OF GOD PERSISTENCE AND CLEARANCE COVID19 By Dr - - PowerPoint PPT Presentation

IN THE NAME OF GOD PERSISTENCE AND CLEARANCE COVID19 By Dr Davoud Esmaeili Fellowship in Clinical Laboratory Sciences Attachment ACE2 NANA CD13 SPIKE HE Fc IgG NANA Tight att. Persistent COVID-19 incubation period Strong


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IN THE NAME OF GOD

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PERSISTENCE AND CLEARANCE COVID19

By Dr Davoud Esmaeili Fellowship in Clinical Laboratory Sciences

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Attachment

SPIKE ACE2 NANA CD13 Fc IgG Tight att. HE NANA

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Persistent COVID-19

  • incubation period
  • Strong Attachment
  • Enveloped
  • Budding
  • PH
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ACE2 Receptors in TUBULE

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Immunohistochemistry analyzed SARS- CoV-2 NP antigen in kidney tissues

arrow indicated NP positive tubules and arrow head indicated viral inclusion body

Tubular

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COVID19& Tubule

Receptor

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Immunohistochemistry analyzed lymphocytes and the complement C5b9 in kidney tissues. The expression of (A) CD68, CD8 and CD56; (B) C5b-9 in kidney tissues from COVID-19 patients

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Lymphocyte & Macrophage Infiltration

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COVID19 & Golgi, ER

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Sepsis

Cytokine Storm Immune Complex

Hyper coagulopathy Hypertension Hypotension Ren-Ang-Ald

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Clearance Immune Response

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IMMUNITY to COVID19

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Kidney

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Immunity double-edged sword

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Clearance Drug

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COVID-19 Persistent in Kidney? COVID-19 Clearance? Drugs? COVID19 Prevention? Disinfectant?

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Thank you for your attention