Funding of Infection Research in Germany PD Dr. Barbara Junker - - PowerPoint PPT Presentation

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Funding of Infection Research in Germany

PD Dr. Barbara Junker DLR Project Management Agency

AMR INTERGOVERNMENTAL WORKSHOP PARIS, 17.11.15

German Research Foundation (DFG) (project funding) Universities

(main financial support from the Länder)

Institutes of the Länder Fraunhofer Society

(33% FG and Länder, 66% contract research)

Leibniz Association

(50 % FG: 50 % Länder)

Max Planck Society

(50 % FG: 50 % Länder)

Helmholtz Association

(90% FG: 10 % Länder)

Federal Research Institutes

(RKI, PEI, FLI etc.)

Federal States – Länder Project funding Institutional funding Federal Government Project funding Institutional funding

Research Funding in Germany

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Health Research Framework Programme of the Federal Government

Health Research (2013: 252 Mio €) Biomedical Research (2013: 128 Mio. €)

http://www.bmbf.de/en/healthresearch.php implemented by Federal Ministry of Education and Research (BMBF)

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• 1. The structural challenge:

Focussed research into major diseases

• 2. The research challenge:

Individualised medicine

• 3. The prevention challenge:

Research into prevention and nutrition

• 4. The system challenge:

Research into health care

• 5. The innovation challenge:

The health care industry

• 6. The global challenge:

International cooperation in health research Challenges and Fields of Action

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• The aim is to provide improved medical treatment in order to enhance

people's quality of life

• Closer networking of expertises, disciplines and institutions will

ensure the quick translation of research results into medical care

• Large structural funding measures include the German Centers for

Health Research

Combating diseases – the idea behind the German health research program

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The German Centers for Health Research

Overview

Six German Centers for Health Research have been launched according to the major diseases:

• cancer
• cardiovascular diseases
• diabetes
• infectious diseases
• lung diseases
• neurodegenerative diseases

Strategic aim is to bring together the best university and non-university partners across Germany

German Centre for Cardiovascular Research German Centre for Diabetes Research German Centre for Lung Research German Centre for neurodegenerative diseases German Centre for Infection Research German Consortium for Translational Cancer Research

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• Short Term:

Integrate knowledge and join forces in infection research Integrate research infrastructures and facilitate access to cohorts Establish new career paths with a focus on translation

• Middle Term:

Increase the number of clinical trials Provide novel research infrastructures to the community Facilitate industry co-operations (one-portal, common IP-management)

• Long Term:

Provide more efficient prevention, diagnosis and treatment strategies and reduce number of deaths by infections Novel comprehension of translational research through new generation scientists, i.e. Clinical Scientists The German Centers for Health Research

Intention

Translation – the guiding idea

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German Center for Infection Research

Key Figures

The German Center for Infection Research…

• … was founded 2012
• … consists of seven partner-sites comprising 35 research groups
• … possesses twelve associated members
• … has had a budget-increase from 16 Mio. € (2013) to 39 Mio. € (2015)
• … will be funded with an annual budget of 39 Mio. € starting 2015 –

90 % are provided by the Federal Government and 10 % are provided by the Federal States (Länder) as permanent, institutional funds in a joint effort

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German Center for Infection Research

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• Create synergies for medical progress across

borders

• Networking of research funders, researchers, and

infrastructures through: ERA-nets, JPIs, EDCTP, ESFRI Informal cooperations, e.g. with ANRS

Health Research Framework Programme

The global challenge: International cooperation in health research

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DART 2020

The German Antimicrobial Resistance Strategy

Goals:

• Strengthening the One Health approach nationally and

internationally

• Recognising changes in resistance at an early stage
• Retaining and improving therapy options
• Breaking chains of infection early and avoiding infections
• Raising awareness and strengthening skills
• Supporting research and development

National strategy in line with the WHO global action plan Ministries of Health, Food and Agriculture, and Education and Research

Research on Zoonoses Research Agreement between

• Federal Ministry for Education and Research
• Federal Ministry of Health
• Federal Ministry of Food and Agriculture
• Federal Ministry of Defence

German Research Platform for Zoonoses

• The German Research Platform for Zoonoses is an information and service
• network. The objective of the platform, which now has over 500 members, is to

increase the exchange of experiences at national and international levels and thus intensify research activities in the field of zoonoses research, promoting broad horizontal cross-linking of human and veterinary medicine. “A melting pot for zoonoses researchers.”

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Research on Zoonoses Funding of the platform, research consortia, single projects, work shops by the 3 Ministries

• ca. 80 Mio. Euros spent from 2007 – 2017

New calls are planned to be announced in 2015

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• To determine the prevalence of ESBL-producing bacteria in humans (hospital,

ambulant, community), animals (livestock, pets), food and the environment

• To identify the respective resistance genes and analyse their transferability

between enterobacteriaceae

• To compare genetic relationship of bacterial isolates and resistance gene carrying

plasmids in different settings (human, animal, environment) to evaluate the transmission pathways of ESBL-resistance

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ESBL and (fluoro)quinolone Resistance in Enterobacteriaceae

MedVet‐Staph: Interdisciplinary Research Network on the Zoonotic Impact of Staphylococcus aureus/MRSA

• To identify the risk MRSA which emerged in livestock and companion animals
• To identify the contribution of clinically relevant antibiotic resistance genes

contained by staphylococci from animals to antibiotic resistance development in staphylococci of human

• To further develop targeted antibiotic resistance surveillance as well as strategies

for diagnostics, intervention, and therapy as one health approach.

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Ressources

• 960 employees
• 1,22 Mrd. Euro funding/y
• more than 10,000 projects/y
• Locations at Bonn, Köln, Berlin

Stand: 12/2012

Project Management Agency within the German Aerospace Center

Bilder: PT-DLR, DLR, Getty Images, Thinkstock, Lufthansa, Schenker AG, EU Kommission, Foto|Edhar – fotolia, GTAG.net Fotomontage: PT-DLR

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Thank you for your attention!

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