FOOD SAFETY CII - 9TH NATIONAL FOOD SAFETY AND QUALITY SUMMIT - - PowerPoint PPT Presentation

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FOOD SAFETY CII - 9TH NATIONAL FOOD SAFETY AND QUALITY SUMMIT - - PowerPoint PPT Presentation

SCIENCE BEHIND FOOD SAFETY CII - 9TH NATIONAL FOOD SAFETY AND QUALITY SUMMIT DECEMBER 2, 2014 NEW DELHI, INDIA Nimish Shah Director, Safety and Environmental Assurance Centre Unilever R&D Bangalore 64, Main Road, Whitefield Bangalore


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SCIENCE BEHIND FOOD SAFETY

CII - 9TH NATIONAL FOOD SAFETY AND QUALITY SUMMIT DECEMBER 2, 2014 NEW DELHI, INDIA

Nimish Shah

Director, Safety and Environmental Assurance Centre Unilever R&D Bangalore 64, Main Road, Whitefield Bangalore 560066 E Mail: nimish.shah@unilever.com

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OUTLINE

  • Pathogens and their health impact
  • Risk Assessment – Applying science to

determine safety thresholds

  • Knowledge and expert tools
  • Surveillance and public health
  • Food safety expertise
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FOOD ANALYSIS: SPEED AND SENSITIVITY

PCR/ Antibody based tests allow detection of single/ very few numbers of pathogens in matter of minutes-hours

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SEAC

FOOD-BORNE PATHOGENS & HEALTH IMPACT

Micro-organism* Illnesses (%)

  • Hospital. (%)

Death (%) Bacillus cereus 0.198 0.014

  • Staph. aureus

1.3 2.9 0.107 Yersinia enterocolitica 0.628 1.8 0.126

  • Cl. botulinum

0.00042 0.076 0.246

  • Cl. perfringens

1.8 0.064 0.360 Vibrio 0.038 0.203 1.7

  • E. coli (path.)

1.3 4.6 4.3 Campylobacter 14.2 17.3 5.7

  • L. monocytogenes

0.018 3.8 27.5 Salmonella 9.7 25.7 30.4

*Infectious dose varies from pathogen to pathogen

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EXAMPLE 1 - DETERMINING SAFETY THRESHOLD

Chamomile Infusion (similar to tea)

No microbiological standards

Bacillus species found up to 1000 CFU/ ml Bacillus spp. are common in a wide range of environments and raw materials (also in many processed foods) Bacillus cereus, well established as a cause of food- borne illness in humans, could also be present sometimes This pathogen may not be inactivated by the hot water used for infusion making

Question – What is the risk to the consumer drinking the infusion?

SEAC

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EXAMPLE 1 - DETERMINING SAFETY THRESHOLD

Samples in consumer trial contained maximum levels of 3 x103 cfu/ml Immediate consumption - levels will not change Large numbers of B. cereus are required to cause food poisoning Numbers found in foods implicated in B. cereus food poisoning are typically within the range of 105 to 109 cfu/g or ml In outbreaks associated with these organisms, levels were always above 106/g

The health risk to consumers is considered negligible and acceptable at levels <1000/g

SEAC

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Raw material contamination

0.2 0.4 0.6 0.5 1 1.5 2 2.5 3 3.5 4 Bacterial concentration (log cfu/g) Density of Probability

  • B. cereus D-values at 90C
0.2 0.4 0.6 0.8 1 1.2
  • 0.5
0.5 1 1.5 2 2.5

D-values (log min) Density of Probability

EXAMPLE 2 - MANUFACTURING ASPECTS

Variability in spore heat resistance Variability in heat impact Variability in spore levels in ingredients

J.-M. Membré, A. Amézquita, J. Bassett, P. Giavedoni, C. de W. Blackburn, L.G.M. Gorris. (2006) J. Food Prot., 69: 118-129.

Number of surviving spores in contaminated packs

0.05 0.1 0.15 0.2 0.25 0.3 1 3 5 7 9 11

Number of Spores surviving the HT (cfu/g) Density of Probability Only 50% of packs contaminated

Number of surviving spores in contaminated packs

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Source: FAO/WHO Listeria monocytogenes risk assessment

% “detective” servings Predicted no. of listeriosis cases * when: absent in 25 g < 100/g 0.002 0.02 0.00001 0.006 0.025 0.0001 0.04 0.061 0.001 0.42 0.44 0.01 4.23 4.25 0.1 42.3 42.3 1 419 419

“Defective” servings assumed to contain ≥ 106 L.m./g * In the USA per Mill population

Example 3 - Listeria Monocytogenes

Influence of microbial limit on incidence

% “defective” servings

No increase in predicted disease outcomes despite relaxing pathogen limit

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QUANTIFYING RISKS - MODELING

Serving size ppm/ ppb

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SCIENTIFIC TOOLS

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SURVEILLANCE OF FOOD-BORNE ILLNESS: EXAMPLE 1 – CDC (USA)

http://www.cdc.gov/foodnet/data/trends/tables/2013/table2a-b.html#table-2b

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SURVEILLANCE OF FOOD-BORNE ILLNESS: EXAMPLE 2 – AUSTRALIA

http://www.health.gov.au/internet/main/publishing.nsf/Content/cda-cdi3603-pdf-cnt.htm/$FILE/cdi3603a.pdf

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SURVEILLANCE OF FOOD-BORNE ILLNESS: INSIGHTS ON COSTS & BENEFITS

http://www.food.gov.uk/sites/default/files/multimedia/pdfs/fds2015.pdf

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SEVERAL FOOD R&D INSTITUTIONS: FOCUS ON FOOD SAFETY INADEQUATE (?)

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Science Based Food Safety: A National Priority

Establishment of FSSAI – a key milestone for the country Recommendations:

  • Evolve a modern science-based food safety system
  • Strengthen health surveillance systems
  • Robust assessment of health issues linked to foods
  • Build global capabilities – resources, expertise and infrastructure

Risk Assessment , Management and Communication Capabilities & Mindset Collaboration and Networking National & International – consider instituting a national food safety network

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THANK YOU

Acknowledgements:

Paul Hepburn & Alejandro Amezquita