Evan H. DeLucia February 2018 Genomic Sciences Program PI Meeting - - PowerPoint PPT Presentation

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May 15, 2023 589 likes •796 views

Evan H. DeLucia February 2018 Genomic Sciences Program PI Meeting FEEDSTOCK ICON HERE Producing oil in the plant factory Producing oil in the plant factory Zale et al. 2016. Plant Biotech. J. Illinois Biological Foundry for Advanced

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Evan H. DeLucia February 2018 Genomic Sciences Program PI Meeting

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FEEDSTOCK ICON HERE

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Producing oil in the plant factory

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Zale et al. 2016. Plant Biotech. J.

Producing oil in the plant factory

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Illinois Biological Foundry for Advanced Biomanufacturing (iBioFAB)

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iBioFAB: A scalable and automated platform for metabolic engineering

Ethanol fermentation with 1.1% (v/v) acetic acid by the wild type and a mutant yeast strain isolated using iBioFAB.

Si et al. Nature Communications DOI: 10.1038/ncomms15187

fully automated workflow for yeast strain

engineering

CRISPR-assisted δ-integration to enable

automation

diverse genome-scale mutations (over-

expression and down-regulation)

a yeast strain with the highest reported

acetic acid resistance was generated within a month, which harbors 68 kb mutations targeting 26 different genetic targets

Platform can be used to rapidly engineer

model and non-model yeasts for industrial applications

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3.8 ha 0.7 ha

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Hudiburg et al. 2016. Nature Energy

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Hudiburg et al. 2016. Nature Energy

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OUR TEAM

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