Comprehensive Canada-Kyrgyz Biosecurity, Biocontainment & - PowerPoint PPT Presentation

Comprehensive Canada-Kyrgyz Biosecurity, Biocontainment & Biosafety Cooperation

The Global Partnership Under Canada’s leadership, the G8 launched the Global Partnership Against the Spread of Weapons and Materials of Mass Destruction at the 2002 G8 Summit in Kananaskis • Kananaskis Statement We commit ourselves to prevent terrorists, or those that harbour them, from acquiring or developing nuclear, chemical, radiological and biological weapons; missiles; and related materials, equipment and technology. 2

The Global Partnership Kananaskis Summit (2002) • G8 committed up to US $20 billion • 23 partner countries today • Canada committed $1 billion • Principles: biosafety & biosecurity Hokkaido Summit (July 2008) • We also recognize that the GP must evolve further to address new, emerging risks worldwide if we are to prevent terrorists or those that harbour them from acquiring chemical, biological, radiological, nuclear weapons and/or missiles. • G8 REPORT ON THE GLOBAL PARTNERSHIP 3

Comprehensive Biosecurity and Biosafety Program for the Kyrgyz Republic • Canada and the Kyrgyz Republic are cooperating to implement a comprehensive biological security/safety and non-proliferation program in the Kyrgyz Republic • Objective is to reduce the threat of theft, sabotage and/or terrorist acquisition of vulnerable pathogen collections • Important human and animal health benefits • Canada is prepared to provide up to $40 Million for: 4

The Kyrgyz Republic • Population ~ 5 million • Size ~ 200,000 km 2 • Terrain - 94% mountainous • Agriculture >1/3 of GDP • Ratified BTWC in 2004 Deadly diseases in Kyrgyzstan: • Anthrax • Plague • Brucellosis • FMD • Rabies • Avian Influenza 5

Kyrgyz Bio Labs Ministry of Health Ministry of Agriculture Academy of Sciences • Expertise in working safely with dangerous endemic diseases (e.g. anthrax, brucella, plague, CCHF, FMD, Sheep pox) • No lab-acquired infections despite working with these pathogens on open-bench (no biosafety cabinets, no secondary containment systems) • Excellent microbiological technique to reduce aerosols at source • But there is room for improvement! 6

Canada-Kyrgyz Treaty AGREEMENT BETWEEN THE GOVERNMENT OF CANADA AND THE GOVERNMENT OF THE KYRGYZ REPUBLIC CONCERNING COOPERATION IN THE FIELD OF BIOLOGICAL SECURITY AND BIOLOGICAL SAFETY • Provides necessary legal framework for implementation of cooperative projects. • In the Preamble, both Parties affirm their “ DESIRE to contribute to the strengthening of the Convention on the Prohibition of the Development, Production and Stockpiling of Bacteriological (Biological) and Toxin Weapons and on Their Destruction done at London, Moscow and Washington on 10 April 1972.” • Other Key provisions include: • Peaceful Uses • Taxation • Indemnification • To be signed in Bishkek August 2008 • Ratification in Fall 2008 • Administrative application to allow critical physical security upgrades at several facilities 7

New Biosafety Level 3 Laboratory Цель Purpose � Увеличен ие биологической � Enhance biosecurity, biosafety безопасности , биологическая & biocontainment in Kyrgyz безопасность и Биологическое Сдерживание в Киргизской Republic Республике � Central Repository to � Центральный Склад , consolidate BSL3 Pathogens чтобы объединить � Reduce Threat of release of Болезнетворные dangerous pathogens микроорганизмы BSL3 л аборатории Mandate of New Lab � Уменьшит ь Угрозу выпуска опасных болезнетворных � serve as the central repository, микроорганизмов consolidating all dangerous Мандат Новой pathogens and BSL3 activities Лаборатории in the Kyrgyz Republic. � conduct human and animal � Служит ь центральным складом , объединяя все опасные health diagnostics in a secure болезнетворные микроорганизмы и and safe manner действия BSL3 лаборатории в Киргизской Республике 8 � Проведите диагностику здоровья

General Concept for New Laboratory • Based on Canadian Science Centre for Human and Animal Health. Winnipeg, Canada • Expected construction cost = $30 million Achieving a successful BSL3 facility in Kyrgyzstan where there are technical and resource limitations depends on careful advance planning during programming phase. Laboratory Programming Design Construction Commissioning & Certification 9

Key Considerations Security for the nation’s collection of dangerous pathogens Perimeter Security Building Entry Office & Support BSL 2 BSL 3 Repository 10

Key Considerations Balance: safe and secure facility that can be successfully certified & facility that can be sustained in long term Cost-effective to maintain and operate! 11

12 Human Health Floor 1 – Kyrgyz Laboratory Shared support Shared entry Animal Health

Suite Concept • Separate virology and bacteriology suites – Each suite has multiple lab units Bacteriology Virology A culture Cell culture for of Bacillus growing virus anthracis 13

Program Areas 759 Security Admin & Lab The new SQ.M. Offices Kyrgyz 980 SQ.M. BSL 2 Laboratories laboratory 992 SQ.M. BSL 3 Laboratories requires more BSL3 space 192 SQ.M. ABSL 3 Holding / Procedure to diagnose 530 SQ.M. Building & Lab indigenous Support agents 14

Laboratory Project Schedule Phase Phase Year 1 Year 1 Year 2 Year 2 Year 3 Year 3 Year 4 Year 4 Completed Dec Program/Feasibility Program/Feasibility 2007 Schematic Design Schematic Design Begin July 2008 Design Development Design Development Construction Documents Construction Documents Bid and Negotiate Bid and Negotiate Begin July 2009 Construction Construction Commissioning Commissioning 15

A Joint Effort • Canada and the Kyrgyz Republic have established a very effective working relationship • Canada-Kyrgyz Biological Laboratory Working Group • Meets every 2 months in Bishkek • Participation by all relevant Kyrgyz ministries and agencies • Stakeholder input and buy-in at all phases of projects • Support from Senior Leadership • Shared commitment to identifying “Kyrgyz solutions” • Twinning Program with Winnipeg Laboratory • Coordination & Cooperation with Others • World Bank • France (INSERM Lab) 16

Other Biosafety Cooperation Training Guidelines Development & modernization • KSCQZD Training of guidelines, Center, Almaty standards and regs on biosafety • Annual Training Plans & biosecurity in • Courses & Conferences Kyrgyz Republic • Resources Associations • International Affiliations • BACAC 17

Scientific Cooperation • Canadian funded Science Projects (ISTC): – KR1122 : Biotechnological Approaches to the Creation of New Botanical Pesticides and Molecular-Biological Aspects of Their Influence on Harmful Organisms – KR1327 : The estimation of Potential Biological Danger from Natural Arbovirus Foci in the Kyrgyz Republic with the help of Modern Molecular-Genetic Methods – KR1325 : Enhancement of FMD Control Program in Kyrgyzstan – KR1389 : Monitoring Epizootic Conditions and Prevention of the Occurrence of Rabies in People and Animals – KR1429 : Epidemiological Monitoring of Avian Flu Virus Circulation in the Nature, an Estimation of Biological Danger of the Pestholes in KR • Total Canadian funding = $1.7 million 18

Conclusion • Canada-Kyrgyz cooperation to enhance Biosafety & Biosecurity has many benefits: – Increased security • National, regional and international – Public and animal health • National and regional implications – Scientific advancement and exchange (Article X) – Strengthened bilateral relations 19