CO COVID ID-19 19 Where are we with COVID-19? What can you tell - PowerPoint PPT Presentation

CO COVID ID-19 19 Where are we with COVID-19? What can you tell us about the CO COVID-19 19 vaccine ine?

COVID-19 in Arizona • 182,203 cases overall – Confirmed and probable – A person is counted once, no matter how many tests • 3,932 deaths Data updated: 8/5/20

Links to Data Sources • AZ Department of Health Services – Data Dashboard • CDC Data • Johns Hopkins University

Summary of COVID-19 Vaccines August 5, 2020 Presenting To TAPI Tips Karen Lewis, M.D. | Immunization Medical Director

Coronaviruses • Common colds (4) • Severe Acute Respiratory Syndrome (SARS) • Middle East Respiratory Syndrome (MERS) • 2019 Novel Coronavirus CDC PHIL 18110

Novel Coronavirus Naming COVID-19 SARS-CoV-2

Spike Protein Used to Enter Cell PHIL #18115

Vaccine Safety • Preclinical animal studies • Phase 1, 2, 3 • Food and Drug Administration approval • CDC recommendations • Post-licensure monitoring

mRNA and DNA in Cells PHIL #22200

COVID-19 Vaccine Non-replicating Viral Vector Chimpanzee Adenovirus DNA SARS-CoV2 Spike Protein DNA Chimp Adenovirus DNA SARS-CoV2 Spike Protein Chimp Adenovirus DNA mRNA mRNA mRNA Spike Proteins

mRNA COVID-19 Vaccines Pfizer diagram

mRNA Codes for Spike Protein Pfizer diagram

COVID-19 Vaccines Spike Proteins + Adjuvant Spike proteins

DNA Vaccine • DNA plasmid with instructions for spike protein • Intradermal • Room temperature www.prnewswire.com

COVID-19 Vaccines Operation Warp Speed FDA EUA RESOURCES COLLABORATION APPROVAL

Still Under Study • One or two doses • Handling requirements • Fever, local reactions, etc. • Efficacy • Length of immunity

Flu Shots for Everyone This Year! www.vaccinefinder.org

Po Poll What are your thoughts on recommending the COVID-19 vaccine when it’s available?

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Best Be t Pr Practi ctices ces in in Immuniza unization tion Del elivery ivery in in Ar Ariz izona na What would it take for 90% 0% of my patients to be up to dat ate on their immunizations?

Dr. Daniel T. Cloud Awards 30