Chemspace Framework-Derived Set Description We are willing to - PowerPoint PPT Presentation

Mar 13, 2023 •187 likes •261 views

Chemspace Framework-Derived Set Description We are willing to provide our users with various tools and services to simplify selection of the compounds from our database. Among the tools, we have fast online chemical search, custom

Chemspace Framework-Derived Set
Description We are willing to provide our users with various tools and services to simplify selection of the compounds from our database. Among the tools, we have fast online chemical search, custom library preparation, compound sets, – to name a few. Please discover our Framework-Derived Set – a new approach we offer to surf the Chemspace database. This set is a small but diverse representative library of the Chemspace Screening set. We believe that library design based on the frameworks makes hit expansion and structure-activity studies easy to achieve.
Selection Compound selection strategy: Murcko Frameworks (MFs) that are shared between at least 20 compounds • Only unique MFs – compounds that have derived from frameworks • available only at Chemspace Library size : 824 963 compounds 18 796 Murcko Frameworks You can order full set or selected subset based on your criteria; all compounds are supplied as powders, solutions, or dry films. Please contact us at sales@chem-space.com for more information.
Chemspace Compound sets Discover our Fragment Libraries : General Fragments Fluorine and Heavy Fragments • • 3D-Shaped Fragments Selected Fragments • • Acid and Amine Fragments Singleton Fragments • • Covalent Fragments Saturated and Spiro Fragments • • All libraries’ names are clickable links. Visit www.chem-space.com/flyers to find more Chemspace presentations!
Chemspace Compound sets Discover our Screening compounds : ChEMBL analogs High QED compounds • • CNS-Focused library Phenotypic Screening set • • Covalent Modifiers PPI Modulators • • Drug Impurities Pre-Plated compounds • • Drug Repurposing RNA-Targeted library • • Framework-Derived set Virtual Screening set • • All libraries’ names are clickable links. Visit www.chem-space.com/flyers to find more Chemspace presentations!
Thank You! The Chemspace Team

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