Cervical Cancer Situation in Latin America and the Caribbean and - - PowerPoint PPT Presentation

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Cervical Cancer Situation in Latin America and the Caribbean and - - PowerPoint PPT Presentation

Cervical Cancer Situation in Latin America and the Caribbean and PAHO/WHO Recommendations for the Way Forward Silvana Luciani Advisor, chronic disease prevention and control project Pan American Health Organization/World Health Organization


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Silvana Luciani Advisor, chronic disease prevention and control project Pan American Health Organization/World Health Organization

Cervical Cancer Situation in Latin America and the Caribbean and PAHO/WHO Recommendations for the Way Forward

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PRESENTATION OVERVIEW

  • Burden of cervical cancer in Latin America

and the Caribbean (LAC)

  • Programmatic response to cervical cancer
  • PAHO/WHO strategy for comprehensive

cervical cancer prevention and control

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POPULATION)

(thousands))

N.Am:))347,500) LAC:))))588,500)

HIGHLIGHTS OF LAC REGION

MATERNAL)MORTALITY) RATIO)(100,000))

N.Am:))12) LAC:))))74)

INFANT)MORTALITY)RATE)

(1,000))

N.Am:)))6.5) LAC:)))))18.7)

GROSS)NATIONAL)INCOME)

N.Am:))$46,000) LAC:)))$7,000)

Source:(PAHO(Health(Situa2on(in(the(Americas,(Basic(Indicators,(2011(

CANCER)MORTALITY)RATE) )(100,000)populaLon))

N.Am:))))186) LAC:)))))))))94)

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CERVICAL CANCER IN THE AMERICAS

Age)standardized)mortality)rate))

NORTH AMERICA:

12,300 new cases per year 4,500 deaths per year

Latin America and the Caribbean:

68,000 new cases per year 31,400 deaths per year

Source:(Globocan(2008(

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7.5 9.4 9.9 10.1 11.2 13.3 14.1 15.9 19.8 20.1 30.2 33.2 35.4 36.8 10 20 30 40 Perú Mexico Canada Belize Chile USA Brasil Colombia Paraguay Argentina CostaGRica Guatemala TrinidadG&G Tobago Honduras

HPV(PREVALENCE((%)(AMONG(WOMEN(WITH(NORMAL(CYTOLOGY(

Source:(ICO/WHO((Summary(Report(for(the(Américas,(2009(

HPV PREVALENCE IN THE AMERICAS

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Source:(Globocan(2008(

CERVICAL CANCER INCIDENCE AND MORTALITY BY AGE IN LAC

Women are in the prime of their lives when affected by cervical cancer

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COMPREHENSIVE CERVICAL CANCER PROGRAMS

COMMUNITY PRIMARY HEALTH CARE SECONDARY HEALTH CARE TERCIARY HEALTH CARE

PRIMARY(PREVENTION( ( SCREENING(&(EARLY( DETECTION (( DIAGNOSIS,(TREATMENT(&(PALLIATIVE(CARE( ( U Health(educa2on( U Counselling( U HPV(vaccina2on( UScreening(of(women(at( risk:(Pap(or(HPV(or(VIA(

UScreen(and(treat(

UCytology(Labs( UColposcopy/biopsy( UPathology(labs( UCryotherapy/LEEP( USurgery,(radiotherapy,(chemotherapy( UPallia2ve(care(

ORGANIZED)PROGRAM) coverage/quality/follow(up(

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CERVICAL CANCER MORTALITY IN CHILE 1987-2003

1987 1994 1997 2003

Source: Suarez, E. Cervical Cancer:the Chilean perspective, 2007

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TRENDS IN CERVICAL CANCER MORTALITY IN SELECTED LATIN AMERICAN COUNTRIES

2 4 6 8 10 12 14 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 rate/100,000 Argentina Brazil Colombia Costa Rica Mexico source: PAHO Mortality Database, 2012

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socio-cultural barriers

program organization limitations with cytology

BARRIERS TO EFFECTIVE PROGRAMS IN LAC

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OPPORTUNITIES TO IMPROVE PROGRAMS

  • HPV VACCINES)
  • SCREEN & TREAT APPROACH

VIA followed by cryotherapy treatment

  • NEW SCREENING TESTS

HPV DNA Tests, VIA

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Routine HPV vaccine should be included in national immunization programs, if:

  • cervical cancer prevention is a priority;
  • it is feasible and has sustainable financing
  • priority: girls aged 9-13 years
  • catch up: adolescent and young women (14-26)

Screening guideline:

  • 30 years+
  • every 3 years
  • cytology
  • other tests (VIA, HPV, VILI) in pilot projects
  • cryotherapy treatment effective

WHO RECOMMENDATIONS ON CERVICAL CANCER

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  • 1. Conduct a situation assessment
  • 2. Intensify information, education and counseling
  • 3. Fortify screening and pre-cancer treatment
  • 4. Establish or strengthen information systems and cancer

registries

  • 5. Improve access and quality of cancer treatment and of

palliative care

  • 6. Generate evidence for decision making on HPV vaccine

introduction

  • 7. Advocate for equitable access and affordable

comprehensive cervical cancer prevention

PAHO REGIONAL STRATEGY AND PLAN OF ACTION FOR CERVICAL CANCER PREVENTION AND CONTROL

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CERVICAL CANCER PROGRAMS IN LAC

Cytology)tesLng) )Visual)inspecLon)screening)+)cytology) HPV)DNA)tesLng) )Visual)inspecLon)screening)only)

HPV vaccines in national programs Mexico (2008) Panama (2008) Peru (2011) Argentina (2011) Colombia (2012)

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CONCLUSIONS

  • 1. Evidence and tools are available to improve

impact of cervical cancer programs in LAC.

  • 2. Intensified efforts are needed to:
  • organize programs;
  • introduce HPV vaccines;
  • improve screening and treatment.