CASE Presentation Dr Catherine Nyongesa Head Cancer Treatment - - PowerPoint PPT Presentation

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CASE Presentation Dr Catherine Nyongesa Head Cancer Treatment - - PowerPoint PPT Presentation

CASE Presentation Dr Catherine Nyongesa Head Cancer Treatment Centre KNH, CEO Texas Cancer Centre 40 YR OLD MALE , Ca Rectum FIRST VISIT 17-JUL-2017 POST ENDOSCOPY WHICH HISTOLOGY DIFFUSE SHOWED RECTAL ULCER TYPE ADENOCARCINOMA 1/12 POST


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CASE Presentation

Dr Catherine Nyongesa Head Cancer Treatment Centre KNH, CEO Texas Cancer Centre

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40 YR OLD MALE , Ca Rectum

FIRST VISIT 17-JUL-2017 1/12 POST OP

POST ENDOSCOPY WHICH SHOWED RECTAL ULCER

HISTOLOGY DIFFUSE TYPE ADENOCARCINOMA

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status

  • PMHX- NIL SIG
  • NO CORMOBIDITIES
  • NO FAMILY HISTORY
  • Good ECOG 1
  • PR-NED
  • OTHER SYSTEMS NAD
  • METASTATIC WORK UP NEG
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treatment

Wide local excision 23/06/2017 moderately differentiated adenocarcinoma, margins free of tumor RS/CVS/CNS NAD Adjuvant treatment dxt + chemo 1st and last week of dxt

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issues

T2N0M0 Signet ring adenocarcinoma grade 3 Young patient No nodal sampling Surgeon was worried and strongly recommended adjuvant treatment

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treatment

5FU BOLUS 788MG 5FU INFUSION 4728MG LEUCOVORIN 788MG + DXT 50.4Gy/28# CHEMO 2 CYCLE 1ST AND LAST WK OF DXT

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More chemotherapy

Adjuvant chemo continued CAPOX Oxaliplatin 230MG D1 Capecitabine 1500mg bd 14/7 Continue to total 6 cycles

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Last scan 17/01/2019

  • Left rectal wall nodular thickening which abuts

the left meso rectal fascia.

  • Mild surrounding fat stranding? Post treatment

changes or recurrence.

  • Clinically NED.
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Duration of adjuvant chemo

  • Follow up unreliable, returned to his home

country.

  • Now 1.5 years post op
  • Raising funds for endoscopy
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adverse features

  • On pathology, TEM plus salvage (or adjuvant)

CRT in perioperative high-risk patients (but unproven benefit—with high risk of local recurrence for pT2)

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THANK YOU !!!