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Building Taiwan Health Grid for Health Decision Making Graduated Institute of Medical Informatics Taipei Medical University, Taipei, Taiwan Yu-Chuan (Jack) Li, M.D., Ph.D. Seventeen Chen, M.S. Agenda Taiw an I ntroduction Taiw an I


  1. Building Taiwan Health Grid for Health Decision Making Graduated Institute of Medical Informatics Taipei Medical University, Taipei, Taiwan Yu-Chuan (Jack) Li, M.D., Ph.D. Seventeen Chen, M.S.

  2. Agenda Taiw an I ntroduction � Taiw an I ntroduction � TAIWAN TAIWAN Health Grid @ Taiw an � Health Grid @ Taiw an � Conclusion � Conclusion �

  3. Brief View of Taiwan � Total population: 2 2 .5 m illion � The area approxim ately TAIWAN TAIWAN 3 6 ,0 0 0 sq. km � About 3 9 4 km long and 1 4 4 km wide � Temperatures ranging from 2 8 deg C in July to 1 4 deg C in January

  4. Formosa, A Beautiful Island TAIWAN TAIWAN

  5. World’s highest building: Taipei 101 � 507 meters � Offices, hotels and mall (now open) TAIWAN TAIWAN

  6. National Health Insurance � Department Of Health has Bureau of NHI. � National Health Insurance for all people in National Health Insurance for all people in � Taiwan since 1995 Taiwan since 1995 TAIWAN TAIWAN � NHI IC Card are used all over Taiwan on Jan. 1, 2004.

  7. NHI IC Card TAIWAN TAIWAN

  8. NHI IC Card TAIWAN TAIWAN

  9. Background � Biomedical data � Scale, Complexity, Timeliness � Massive data and heavy computation TAIWAN TAIWAN � Collaboration between hospitals and research/ education institutes � Grid for large data and computing power

  10. Massive Data � National Health Insurance DB: 4TB � Interactive Clinical DataBank: 20GB TAIWAN TAIWAN � CasImage: 3GB � Visible Human Project: 40GB � Dental Image Database � Real Clinical Data: � Two teaching hospitals of TMU: over 300GB of clinical data

  11. Interactive Clinical Image Databank TAIWAN TAIWAN

  12. CasImage of HUG TAIWAN TAIWAN

  13. Estimate medical data of Taiwan � Outpatient visits: 300 millions per year � Inpatient stays: 2.8 millions per year. � ~ 900TB image data per year TAIWAN TAIWAN � ~ 30TB text data per year � ~ laboratory data up to 1 billion records and size 1.2TB per year � Grow exponentially in the next 5 years when electronic health record matures

  14. Health Grid at Taiwan Real connection between hospitals and researchers Institute Hospital Department TMU TMUH CBI TAIWAN TAIWAN WFH BCC NTU NTUH NTUCC Academia ASCC Sinica IIS NCHC MMH …. …. UGH ….

  15. TMU & GIMI � Taipei Medical University � Graduated Institute of Medical Informatics (GIMI) is the first TAIWAN TAIWAN graduated school of medical informatics in Taiwan since 1998 � Center for Biomedical Informatics � Bioinformatics Computer Center � Staff’s computers and computer rooms, about 300+ nodes

  16. NTU � National Taiwan University � First University in Taiwan TAIWAN TAIWAN � 200+ nodes testing Grid on Chemistry, Physics, Bioinformatics � 8 Computer rooms in NTU Computer Center, 400+ computing nodes available

  17. Academia Sinica � Already collaborate with CERN on High Energy Physics Grids TAIWAN TAIWAN � Academia Sinica Computing Centre � Institute of Information Science

  18. Networking Environment TAIWAN TAIWAN

  19. Collaboration People � WFH & TMU: Yu-Chuan Li, MD. PhD. � TMUH: Li Liu, PhD. � NTU & NTUH: Feipei Lai, PhD. TAIWAN TAIWAN � Academia Sinica: Simon Lin PhD. � IIS: Dai-Wei Wang, PhD. � GIMI: All faculty � University of Geneva : Dr. Henning Muller

  20. Scenario: Carpal Tunnel Syndrome � A physician of rehabilitation may want to know: � Percentage of different treatment on CTS in TAIWAN TAIWAN whole Taiwan: � Operation, � Rehabilitation, � Traditional Chinese medicine (e.g. acupuncture) � The outcome and return-to-hospital rate of each treatment options for a patient with specific age and occupation � The rate of CTS and other RSI

  21. HealthGrid Can help on CTS � For physicians � Choose optimal treatment for individual patient TAIWAN TAIWAN � For patients � Get better medical care � For health policy maker � Make future public health policies

  22. Scenario: A 58 year-old female � Lab Data: cholesterol 500mg/ dl � A doctor may want to know: TAIWAN TAIWAN � The percentage of people who eventually get Coronary Artery Disease � Their treatment options � Medication usage… etc. � Provide physician to do better medical decision

  23. SARS Damage in Taiwan � Severe Acute Respirator Syndrome during March 2003 TAIWAN TAIWAN � 346 people affected by SARS � 73 people were dead � Including 12 health professionals

  24. HealthGrid for SARS � For health care people � Patient’s History � SARS Chest X-ray Image TAIWAN TAIWAN � Lab Data / biopsy � Information from research labs � Share experience and knowledge to fight SARS! � For researcher � Have enough clinical data to study SARS � For government and the director of health � Prevent SARS epidemic

  25. Possible Applications � CBIR System for Medical Images � Data Mining on Medical Data TAIWAN TAIWAN � Health Insurance Database Research � Aggregated EHR data for medical decision making and public health policy making

  26. MIEC Project � National Medical Information Exchange Center � MIEC is not successful TAIWAN TAIWAN � Hospitals treat health and medical data as their own property � Not willing to share with other hospitals � Concern about privacy, legal and business issues

  27. To Share, or Not to Share � Medical data are sensitive and “proprietary” � No identifiable patient data will be TAIWAN TAIWAN shared � Share the results of computation, not the patient data itself � Privacy enhancing technologies � Multiparty private computation � IIS Cellsecu System

  28. Privacy Enhancing Technology (PET) � De-identification before shipping the dataset: manipulate data so that no TAIWAN TAIWAN individual information can be inferred � Data-centered: to have data processing programs come to the data source and reply the results after finishing processing

  29. CellSecu � A gatekeeper to ensure datasets meet the privacy requirement before releasing � Based on modal logic formalism TAIWAN TAIWAN � Using generalization of attributes to enhance privacy protection � Privacy measurements are based on information theory and benefit gained for dataset receiver � Developed in Academia Sinica Taiwan

  30. Cellsecu � IIS of Academia Sinica � Technology used: TAIWAN TAIWAN � Data de-identification � Encryption technology � Multiparty private computation

  31. Dataset Linkage problem � Linking several dataset can be very useful � Linkage is prohibited by law in many places due to privacy concerns TAIWAN TAIWAN � Private multiparty computation (MPC) protocols might remedy the situation � We plan to study the feasibility and impact of applying MPC on Grids

  32. Research of Health Grid EIS TAIWAN TAIWAN HIS PACS Grid Computing Technology PIS NIS LIS

  33. Conclusion � Use Grid technology to collaborate hospitals and academic institute TAIWAN TAIWAN � Build a testbed and demo site of a Taiwan Health Grid � Devise PETs than can be used in this Health Grid � Increase international collaboration

  34. Q & A TAIWAN TAIWAN Welcome to ISGC 2004 in Taiwan! Thanks you!

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