Bridging the Gap: An overview of CPRITs Early Translational - - PowerPoint PPT Presentation
Bridging the Gap: An overview of CPRITs Early Translational Research Award (ETRA) and SEED Award RFAs September 19, 2018 Presented By: James Willson, MD Michael Lang Patty Moore, PhD Rosemary French Bridging the Gap: ETRA and SEED
Presented By: James Willson, MD Michael Lang Patty Moore, PhD Rosemary French
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Drug Discovery Preclinical Clinical Trials FDA Review Mfg. Clinic Ongoing/Indefinite Phase I & II Phase II Phase III 3-6 Years 6-10 Years 0.5-2 Years Discovery Research Translational Research
Largely Public Funded
Largely Industry &
For Profit Funded Phase IV
Timeline Funding Sources Research Stages
5K-10K Compounds 250 5 1 FDA Approved Drug
Drug Development Pipeline
Public &
Private
(Underfunded)
3 “Valley of Death”
Drug Discovery Preclinical Clinical Trials FDA Review Mfg. Clinic Ongoing/Indefinit e Phase I Phase II Phase III 3-6 Years 6-10 Years 0.5-2 Years Basic Research Translational Research Largely Public Funded e.g. NIH, DoD Largely Industry & For Profit Funded Phase IV
Timeline Funding Sources Research Stages
5K-10K Compounds 250 5 1 FDA Approved Drug
Drug Development Pipeline
Public & Private “Valley of Death”
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Drug Discovery Preclinical Clinical Trials FDA Review Mfg. Clinic Ongoing/Indefinit e Phase I Phase II Phase III 3-6 Years 6-10 Years 0.5-2 Years Basic Research Translational Research Largely Public Funded e.g. NIH, DoD Largely Industry & For Profit Funded Phase IV
Timeline Funding Sources Research Stages
5K-10K Compounds 250 5 1 FDA Approved Drug
Drug Development Pipeline
Public & Private (Underfunded) “Valley of Death”
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